| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | Genomic imprinting: parental influence on the genome | Nature Reviews Genetics | 2001 | 2,120 |
| 4 | Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum | Journal of Cell Biology | 2008 | 1,588 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | Molecular definitions of autophagy and related processes | EMBO Journal | 2017 | 1,230 |
| 7 | Heterodimerization is required for the formation of a functional GABAB receptor | Nature | 1998 | 1,104 |
| 8 | Structural Determinants of Phosphoinositide 3-Kinase Inhibition by Wortmannin, LY294002, Quercetin, Myricetin, and Staurosporine | Molecular Cell | 2000 | 1,102 |
| 9 | Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity | Nature Methods | 2014 | 954 |
| 10 | Follicular Helper T Cells | Annual Review of Immunology | 2016 | 912 |
| 11 | FastQ Screen: A tool for multi-genome mapping and quality control | F1000Research | 2018 | 905 |
| 12 | Conservation of methylation reprogramming in mammalian development: Aberrant reprogramming in cloned embryos | Proceedings of the National Academy of Sciences of the United States of America | 2001 | 894 |
| 13 | The Air Noncoding RNA Epigenetically Silences Transcription by Targeting G9a to Chromatin | Science | 2008 | 883 |
| 14 | FastQ Screen: A tool for multi-genome mapping and quality control | F1000Research | 2018 | 865 |
| 15 | Oligodendrocyte dysfunction in schizophrenia and bipolar disorder | Lancet, The | 2003 | 861 |
| 16 | Mapping long-range promoter contacts in human cells with high-resolution capture Hi-C | Nature Genetics | 2015 | 857 |
| 17 | Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27 | Cell | 1994 | 854 |
| 18 | Quantitative Sequencing of 5-Methylcytosine and 5-Hydroxymethylcytosine at Single-Base Resolution | Science | 2012 | 850 |
| 19 | Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress | Molecular Psychiatry | 2004 | 810 |
| 20 | Resetting Transcription Factor Control Circuitry toward Ground-State Pluripotency in Human | Cell | 2014 | 784 |
| 21 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 22 | The H19 lincRNA is a developmental reservoir of miR-675 that suppresses growth and Igf1r | Nature Cell Biology | 2012 | 747 |
| 23 | Exogenous Stimuli Maintain Intraepithelial Lymphocytes via Aryl Hydrocarbon Receptor Activation | Cell | 2011 | 692 |
| 24 | Shorthand notation for lipid structures derived from mass spectrometry | Journal of Lipid Research | 2013 | 689 |
| 25 | A single-cell molecular map of mouse gastrulation and early organogenesis | Nature | 2019 | 658 |
| 26 | Abundant Tau Filaments and Nonapoptotic Neurodegeneration in Transgenic Mice Expressing Human P301S Tau Protein | Journal of Neuroscience | 2002 | 643 |
| 27 | Phospholipid signaling | Cell | 1995 | 629 |
| 28 | Autophagy in major human diseases | EMBO Journal | 2021 | 615 |
| 29 | A novel phosphoinositide 3 kinase activity in myeloid-derived cells is activated by G protein βγ subunits | Cell | 1994 | 611 |
| 30 | Parallel single-cell sequencing links transcriptional and epigenetic heterogeneity | Nature Methods | 2016 | 602 |
| 31 | Ca2+ signalling checkpoints in cancer: remodelling Ca2+ for cancer cell proliferation and survival | Nature Reviews Cancer | 2008 | 600 |
| 32 | Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress | Cancer Cell | 2015 | 596 |
| 33 | dSarm/Sarm1 Is Required for Activation of an Injury-Induced Axon Death Pathway | Science | 2012 | 558 |
| 34 | Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2 | Nature | 2021 | 549 |
| 35 | PDGF stimulates an increase in GTP–Rac via activation of phosphoinositide 3-kinase | Current Biology | 1995 | 531 |
| 36 | Multimodal Influence of Estrogen upon Gonadotropin-Releasing Hormone Neurons | Endocrine Reviews | 1998 | 527 |
| 37 | Beckwith-Wiedemann syndrome and assisted reproduction technology (ART) | Journal of Medical Genetics | 2003 | 524 |
| 38 | PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells | Journal of Experimental Medicine | 2012 | 518 |
| 39 | RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target Sites Independently of PRC2 and H3K27me3 | Cell | 2012 | 513 |
| 40 | scNMT-seq enables joint profiling of chromatin accessibility DNA methylation and transcription in single cells | Nature Communications | 2018 | 513 |
| 41 | Guidelines for the use of flow cytometry and cell sorting in immunological studies* | European Journal of Immunology | 2017 | 505 |
| 42 | Epigenetic Marking Correlates with Developmental Potential in Cloned Bovine Preimplantation Embryos | Current Biology | 2003 | 491 |
| 43 | Calcium microdomains: Organization and function | Cell Calcium | 2006 | 480 |
| 44 | Localization of LRRK2 to membranous and vesicular structures in mammalian brain | Annals of Neurology | 2006 | 479 |
| 45 | The PiGMaP consortium linkage map of the pig (Sus scrofa) | Mammalian Genome | 1995 | 475 |
| 46 | PI4P and PI(4,5)P 2 Are Essential But Independent Lipid Determinants of Membrane Identity | Science | 2012 | 435 |
| 47 | Phospholipid Metabolism Regulated by a Transcription Factor Sensing Phosphatidic Acid | Science | 2004 | 431 |
| 48 | Mitochondrial dysfunction in schizophrenia: evidence for compromised brain metabolism and oxidative stress | Molecular Psychiatry | 2004 | 428 |
| 49 | Quantitative and logic modelling of molecular and gene networks | Nature Reviews Genetics | 2015 | 406 |
| 50 | PI3K signalling in inflammation | Biochimica Et Biophysica Acta - Molecular and Cell Biology of Lipids | 2015 | 380 |
