| # | Title | Journal | Year | Citations |
|---|
| 1 | Universal Definition of Myocardial Infarction | Circulation | 2007 | 2,755 |
| 2 | Fourth universal definition of myocardial infarction (2018) | European Heart Journal | 2019 | 2,687 |
| 3 | Third universal definition of myocardial infarction | Nature Reviews Cardiology | 2012 | 2,615 |
| 4 | COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up | Journal of the American College of Cardiology | 2020 | 2,392 |
| 5 | 2013 Classification Criteria for Systemic Sclerosis: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative | Arthritis and Rheumatism | 2013 | 2,359 |
| 6 | Paced Auditory Serial-Addition Task: A Measure of Recovery from Concussion | Perceptual and Motor Skills | 1977 | 2,055 |
| 7 | Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial | Lancet, The | 2010 | 2,002 |
| 8 | Asian-Pacific clinical practice guidelines on the management of hepatitis B: a 2015 update | Hepatology International | 2016 | 1,908 |
| 9 | 2013 classification criteria for systemic sclerosis: an American college of rheumatology/European league against rheumatism collaborative initiative | Annals of the Rheumatic Diseases | 2013 | 1,705 |
| 10 | EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists | Rhinology | 2012 | 1,665 |
| 11 | Sofosbuvir for Previously Untreated Chronic Hepatitis C Infection | New England Journal of Medicine | 2013 | 1,605 |
| 12 | European Position Paper on Rhinosinusitis and Nasal Polyps 2020 | Rhinology | 2020 | 1,555 |
| 13 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study | Lancet, The | 2013 | 1,476 |
| 14 | Hydroxyethyl Starch or Saline for Fluid Resuscitation in Intensive Care | New England Journal of Medicine | 2012 | 1,460 |
| 15 | Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome | JAMA - Journal of the American Medical Association | 2009 | 1,416 |
| 16 | Intensity of Continuous Renal-Replacement Therapy in Critically Ill Patients | New England Journal of Medicine | 2009 | 1,288 |
| 17 | Rucaparib maintenance treatment for recurrent ovarian carcinoma after response to platinum therapy (ARIEL3): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 1,261 |
| 18 | Treatment of Venous Thrombosis with Intravenous Unfractionated Heparin Administered in the Hospital as Compared with Subcutaneous Low-Molecular-Weight Heparin Administered at Home | New England Journal of Medicine | 1996 | 1,108 |
| 19 | EPOS 2012: European position paper on rhinosinusitis and nasal polyps 2012. A summary for otorhinolaryngologists | Rhinology | 2012 | 1,086 |
| 20 | Development of a multiple sclerosis functional composite as a clinical trial outcome measure | Brain | 1999 | 1,024 |
| 21 | Metformin versus Insulin for the Treatment of Gestational Diabetes | New England Journal of Medicine | 2008 | 1,023 |
| 22 | Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis | New England Journal of Medicine | 2018 | 1,000 |
| 23 | Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer | New England Journal of Medicine | 2019 | 982 |
| 24 | Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial | Lancet Neurology, The | 2008 | 971 |
| 25 | Serrated Lesions of the Colorectum: Review and Recommendations From an Expert Panel | American Journal of Gastroenterology | 2012 | 948 |
| 26 | Critical Care Services and 2009 H1N1 Influenza in Australia and New Zealand | New England Journal of Medicine | 2009 | 920 |
| 27 | Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA) | Annals of Oncology | 2013 | 895 |
| 28 | Natural history of cervical neoplasia and risk of invasive cancer in women with cervical intraepithelial neoplasia 3: a retrospective cohort study | Lancet Oncology, The | 2008 | 877 |
| 29 | Asian-Pacific consensus statement on the management of chronic hepatitis B: a 2012 update | Hepatology International | 2012 | 874 |
| 30 | Escalated-dose versus standard-dose conformal radiotherapy in prostate cancer: first results from the MRC RT01 randomised controlled trial | Lancet Oncology, The | 2007 | 843 |
| 31 | Hypoglycemia and Risk of Death in Critically Ill Patients | New England Journal of Medicine | 2012 | 827 |
| 32 | Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial | Lancet, The | 2019 | 818 |
| 33 | A Randomized, Controlled Trial of Early versus Late Initiation of Dialysis | New England Journal of Medicine | 2010 | 767 |
| 34 | PATENT FORAMEN OVALE IN YOUNG STROKE PATIENTS | Lancet, The | 1988 | 707 |
| 35 | Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes | New England Journal of Medicine | 2012 | 701 |
| 36 | Nucleotide Polymerase Inhibitor Sofosbuvir plus Ribavirin for Hepatitis C | New England Journal of Medicine | 2013 | 689 |
| 37 | Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19 | JAMA - Journal of the American Medical Association | 2020 | 671 |
| 38 | A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial | Lancet, The | 2008 | 655 |
| 39 | Factors Influencing Mortality in Acromegaly | Journal of Clinical Endocrinology and Metabolism | 2004 | 589 |
| 40 | Efficacy of a quadrivalent prophylactic human papillomavirus (types 6, 11, 16, and 18) L1 virus-like-particle vaccine against high-grade vulval and vaginal lesions: a combined analysis of three randomised clinical trials | Lancet, The | 2007 | 579 |
| 41 | Driver sleepiness and risk of serious injury to car occupants: population based case control study | BMJ: British Medical Journal | 2002 | 577 |
| 42 | Restrictive versus Liberal Fluid Therapy for Major Abdominal Surgery | New England Journal of Medicine | 2018 | 561 |
| 43 | Acute myocardial infarction | Lancet, The | 2008 | 557 |
| 44 | ESPEN guidelines on chronic intestinal failure in adults | Clinical Nutrition | 2016 | 554 |
| 45 | Platelet Inhibition with Cangrelor in Patients Undergoing PCI | New England Journal of Medicine | 2009 | 533 |
| 46 | Comparison of Outcomes Among Patients Randomized to Warfarin Therapy According to Anticoagulant Control | Archives of Internal Medicine | 2007 | 527 |
| 47 | GATA3 haplo-insufficiency causes human HDR syndrome | Nature | 2000 | 516 |
| 48 | Determinants of clinical outcome and survival in acromegaly | Clinical Endocrinology | 1994 | 512 |
| 49 | Randomized trial of bendamustine-rituximab or R-CHOP/R-CVP in first-line treatment of indolent NHL or MCL: the BRIGHT study | Blood | 2014 | 505 |
| 50 | Azithromycin for prevention of exacerbations in non-cystic fibrosis bronchiectasis (EMBRACE): a randomised, double-blind, placebo-controlled trial | Lancet, The | 2012 | 500 |
