| # | Title | Journal | Year | Citations |
|---|
| 1 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 2 | TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Biochemical and Biophysical Research Communications | 2006 | 2,248 |
| 3 | The revised International Association for the Study of Pain definition of pain: concepts, challenges, and compromises | Pain | 2020 | 1,880 |
| 4 | Three Isoforms of Mammalian Hyaluronan Synthases Have Distinct Enzymatic Properties | Journal of Biological Chemistry | 1999 | 768 |
| 5 | Phosphorylated TDP‐43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis | Annals of Neurology | 2008 | 630 |
| 6 | Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains | Acta Neuropathologica | 2003 | 619 |
| 7 | Hematopoietic Stem Cell Transplantation<subtitle>A Global Perspective</subtitle> | JAMA - Journal of the American Medical Association | 2010 | 556 |
| 8 | Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017 | Journal of Atherosclerosis and Thrombosis | 2018 | 541 |
| 9 | Current and future pharmacological therapies for NAFLD/NASH | Journal of Gastroenterology | 2018 | 490 |
| 10 | Testosterone Reduction Prevents Phenotypic Expression in a Transgenic Mouse Model of Spinal and Bulbar Muscular Atrophy | Neuron | 2002 | 452 |
| 11 | Structures of α-synuclein filaments from multiple system atrophy | Nature | 2020 | 446 |
| 12 | 2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A European League Against Rheumatism/American College of Rheumatology/Paediatric Rheumatology International Trials Organisation Collaborative Initiative | Arthritis and Rheumatology | 2016 | 427 |
| 13 | Structure-based classification of tauopathies | Nature | 2021 | 409 |
| 14 | Cooperativity of the glucocorticoid receptor and the CACCC-box binding factor | Nature | 1988 | 408 |
| 15 | X-LINKED RECESSIVE BULBOSPINAL NEURONOPATHY | Brain | 1989 | 396 |
| 16 | Artificial intelligence for diagnosis and grading of prostate cancer in biopsies: a population-based, diagnostic study | Lancet Oncology, The | 2020 | 364 |
| 17 | Mammalian Hyaluronan Synthases | IUBMB Life | 2002 | 359 |
| 18 | 2016 Classification Criteria for Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis | Annals of the Rheumatic Diseases | 2016 | 338 |
| 19 | Prevalence of Myopia and its Association with Body Stature and Educational Level in 19-Year-Old Male Conscripts in Seoul, South Korea | | 2012 | 334 |
| 20 | One million haemopoietic stem-cell transplants: a retrospective observational study | Lancet Haematology,the | 2015 | 329 |
| 21 | Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease | Nature Genetics | 2019 | 328 |
| 22 | Nuclear inclusions of the androgen receptor protein in spinal and bulbar muscular atrophy | Annals of Neurology | 1998 | 324 |
| 23 | Clinical Features, Treatment, and Outcome of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis: A Multinational, Multicenter Study of 362 Patients | Arthritis and Rheumatology | 2014 | 322 |
| 24 | International consensus clinical practice statements for the treatment of neuropsychiatric conditions associated with epilepsy | Epilepsia | 2011 | 315 |
| 25 | Dietary phytochemicals and cancer chemoprevention: a review of the clinical evidence | Oncotarget | 2016 | 309 |
| 26 | Development of Low Rigidity β-type Titanium Alloy for Biomedical Applications | Materials Transactions | 2002 | 301 |
| 27 | Daily Walking Combined With Diet Therapy Is a Useful Means for Obese NIDDM Patients Not Only to Reduce Body Weight But Also to Improve Insulin Sensitivity | Diabetes Care | 1995 | 298 |
| 28 | The 2019 International Society of Urological Pathology (ISUP) Consensus Conference on Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2020 | 292 |
| 29 | Psychometric Validation of the Bangla Fear of COVID-19 Scale: Confirmatory Factor Analysis and Rasch Analysis | International Journal of Mental Health and Addiction | 2022 | 284 |
| 30 | Animal model of axonal Guillain-Barré syndrome induced by sensitization with GM1 ganglioside | Annals of Neurology | 2001 | 280 |
| 31 | Abnormal accumulation of hyaluronan matrix diminishes contact inhibition of cell growth and promotes cell migration | Proceedings of the National Academy of Sciences of the United States of America | 2002 | 276 |
| 32 | Apoptosis is a major mode of cell death caused by ischaemia and ischaemia/reperfusion injury to the rat intestinal epithelium | Gut | 1998 | 272 |
| 33 | Hepatitis B Virus of Genotype B with or without Recombination with Genotype C over the Precore Region plus the Core Gene | Journal of Virology | 2002 | 270 |
| 34 | Clinicopathological features of adult-onset neuronal intranuclear inclusion disease | Brain | 2016 | 268 |
| 35 | Updated estimate of running quark masses | Physical Review D | 1998 | 265 |
| 36 | Exosome secretion is a key pathway for clearance of pathological TDP-43 | Brain | 2016 | 262 |
| 37 | Vitrectomy for Diffuse Macular Edema in Cases of Diabetic Retinopathy | American Journal of Ophthalmology | 1996 | 261 |
| 38 | Characterization of Growth Factor-binding Structures in Heparin/Heparan Sulfate Using an Octasaccharide Library | Journal of Biological Chemistry | 2004 | 260 |
| 39 | Spinocerebellar Ataxia Type 31 Is Associated with “Inserted” Penta-Nucleotide Repeats Containing (TGGAA)n | American Journal of Human Genetics | 2009 | 260 |
| 40 | Hematopoietic stem cell transplantation activity worldwide in 2012 and a SWOT analysis of the Worldwide Network for Blood and Marrow Transplantation Group including the global survey | Bone Marrow Transplantation | 2016 | 259 |
| 41 | Proteoglycan Chemical Diversity Drives Multifunctional Cell Regulation and Therapeutics | Chemical Reviews | 2018 | 253 |
| 42 | Interaction of Iron with Polyphenolic Compounds: Application to Antioxidant Characterization | Analytical Biochemistry | 1998 | 251 |
| 43 | Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75 ngfr , TrkA, TrkB, and TrkC) in the adult human peripheral nervous system and nonneural tissues | Neurochemical Research | 1996 | 250 |
| 44 | Sarcopenia and dysphagia: Position paper by four professional organizations | Geriatrics and Gerontology International | 2019 | 249 |
| 45 | A Novel Mechanism for the Inhibition of Hyaluronan Biosynthesis by 4-Methylumbelliferone | Journal of Biological Chemistry | 2004 | 248 |
| 46 | Mouse cartilage matrix deficiency (cmd) caused by a 7 bp deletion in the aggrecan gene | Nature Genetics | 1994 | 242 |
| 47 | Epidemiological and clinical features of Budd-Chiari syndrome in Japan | Journal of Hepatology | 1995 | 239 |
| 48 | Defect in SHAP-Hyaluronan Complex Causes Severe Female Infertility | Journal of Biological Chemistry | 2001 | 234 |
| 49 | Assessment of job stress dimensions based on the job demands-control model of employees of telecommunication and electric power companies in japan: reliability and validity of the japanese version of the job content questionnaire | International Journal of Behavioral Medicine | 1995 | 231 |
| 50 | C5 palsy after cervical laminoplasty | Journal of Bone and Joint Surgery: British Volume | 2010 | 229 |
