| # | Title | Journal | Year | Citations |
|---|
| 1 | Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding | Science | 2009 | 1,788 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 3 | Sniffing neuropeptides: a transnasal approach to the human brain | Nature Neuroscience | 2002 | 1,162 |
| 4 | Cisplatin Nephrotoxicity: A Review | American Journal of the Medical Sciences | 2007 | 1,035 |
| 5 | Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation | Brain, Behavior, and Immunity | 2011 | 929 |
| 6 | Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy | Clinical Cancer Research | 2009 | 875 |
| 7 | Regulation of the Acute Production of Steroids in Steroidogenic Cells* | Endocrine Reviews | 1996 | 854 |
| 8 | Aripiprazole, A Novel Atypical Antipsychotic Drug with a Unique and Robust Pharmacology | Neuropsychopharmacology | 2003 | 848 |
| 9 | Mitochondrial dysfunction and oxidative stress in metabolic disorders — A step towards mitochondria based therapeutic strategies | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2017 | 842 |
| 10 | International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data | Blood | 2022 | 814 |
| 11 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 12 | StAR Protein and the Regulation of Steroid Hormone Biosynthesis | Annual Review of Physiology | 2001 | 781 |
| 13 | The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR) | Journal of Biological Chemistry | 1994 | 779 |
| 14 | Combined knee loading states that generate high anterior cruciate ligament forces | Journal of Orthopaedic Research | 1995 | 776 |
| 15 | Low-molecular-weight polyethylenimine as a non-viral vector for DNA delivery: comparison of physicochemical properties, transfection efficiency and in vivo distribution with high-molecular-weight polyethylenimine | Journal of Controlled Release | 2003 | 758 |
| 16 | Diagnosis ofStrongyloides stercoralisInfection | Clinical Infectious Diseases | 2001 | 744 |
| 17 | The STROCSS statement: Strengthening the Reporting of Cohort Studies in Surgery | International Journal of Surgery | 2017 | 727 |
| 18 | Impaired DNA Damage Response, Genome Instability, and Tumorigenesis in SIRT1 Mutant Mice | Cancer Cell | 2008 | 715 |
| 19 | Novel insights of dietary polyphenols and obesity | Journal of Nutritional Biochemistry | 2014 | 705 |
| 20 | Herbal Medicinals | Archives of Internal Medicine | 1998 | 702 |
| 21 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 22 | The Effect of Acute Exercise on Serum Brain-Derived Neurotrophic Factor Levels and Cognitive Function | Medicine and Science in Sports and Exercise | 2007 | 659 |
| 23 | Cell Wall and Secreted Proteins ofCandida albicans: Identification, Function, and Expression | Microbiology and Molecular Biology Reviews | 1998 | 648 |
| 24 | The Role of Probiotic Cultures in the Control of Gastrointestinal Health | Journal of Nutrition | 2000 | 647 |
| 25 | Role of Glutamate and NMDA Receptors in Alzheimer’s Disease | Journal of Alzheimer's Disease | 2017 | 627 |
| 26 | Nanoparticle Surface Charges Alter Blood–Brain Barrier Integrity and Permeability | Journal of Drug Targeting | 2004 | 626 |
| 27 | Gastrointestinal Microflora Studies in Late‐Onset Autism | Clinical Infectious Diseases | 2002 | 614 |
| 28 | Staging Dementia Using Clinical Dementia Rating Scale Sum of Boxes Scores | Archives of Neurology | 2008 | 607 |
| 29 | A blood–brain barrier overview on structure, function, impairment, and biomarkers of integrity | Fluids and Barriers of the CNS | 2020 | 575 |
| 30 | Heterogeneous Blood–Tumor Barrier Permeability Determines Drug Efficacy in Experimental Brain Metastases of Breast Cancer | Clinical Cancer Research | 2010 | 559 |
| 31 | Sniffing neuropeptides: a transnasal approach to the human brain | Nature Neuroscience | 2002 | 530 |
| 32 | Nanoparticle Technology for Drug Delivery Across the Blood-Brain Barrier | Drug Development and Industrial Pharmacy | 2002 | 522 |
| 33 | Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications | Drug Discovery Today | 2017 | 520 |
| 34 | The immune cell landscape in kidneys of patients with lupus nephritis | Nature Immunology | 2019 | 501 |
| 35 | Detecting Dementia With the Mini-Mental State Examination in Highly Educated Individuals | Archives of Neurology | 2008 | 486 |
| 36 | The Inflammatory Effect of Nucleus Pulposus | Spine | 1987 | 484 |
| 37 | Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas | Cancer Research | 2005 | 484 |
| 38 | American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock | Critical Care Medicine | 2017 | 475 |
| 39 | Adipose Tissue: The New Endocrine Organ? A Review Article | Digestive Diseases and Sciences | 2009 | 474 |
| 40 | Multiple Signaling Pathways Regulating Steroidogenesis and Steroidogenic Acute Regulatory Protein Expression: More Complicated than We Thought | Molecular Endocrinology | 2005 | 467 |
| 41 | Analysis of the Mitochondrial Membrane Potential Using the Cationic JC-1 Dye as a Sensitive Fluorescent Probe | Bio-protocol | 2019 | 458 |
| 42 | New insights into epididymal biology and function | Human Reproduction Update | 2008 | 457 |
| 43 | Inherent bacterial DNA contamination of extraction and sequencing reagents may affect interpretation of microbiota in low bacterial biomass samples | Gut Pathogens | 2016 | 446 |
| 44 | Probiotics function mechanistically as delivery vehicles for neuroactive compounds: Microbial endocrinology in the design and use of probiotics | BioEssays | 2011 | 445 |
| 45 | Biofilm dispersion | Nature Reviews Microbiology | 2020 | 437 |
| 46 | Strategies to advance translational research into brain barriers | Lancet Neurology, The | 2008 | 432 |
| 47 | Common neurodegenerative pathways in obesity, diabetes, and Alzheimer's disease | Biochimica Et Biophysica Acta - Molecular Basis of Disease | 2017 | 430 |
| 48 | Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids | Nature Genetics | 2012 | 428 |
| 49 | Lichen planus | Journal of the American Academy of Dermatology | 1991 | 426 |
| 50 | NRF2 and NF-қB interplay in cerebrovascular and neurodegenerative disorders: Molecular mechanisms and possible therapeutic approaches | Redox Biology | 2019 | 409 |
