| # | Title | Journal | Year | Citations |
|---|
| 1 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 2 | Metformin: An Old Drug for the Treatment of Diabetes but a New Drug for the Protection of the Endothelium | Medical Principles and Practice | 2015 | 1,060 |
| 3 | Integrative Analyses of Colorectal Cancer Show Immunoscore Is a Stronger Predictor of Patient Survival Than Microsatellite Instability | Immunity | 2016 | 814 |
| 4 | Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 786 |
| 5 | Weight and Metabolic Outcomes 12 Years after Gastric Bypass | New England Journal of Medicine | 2017 | 621 |
| 6 | Global and National Burden of Diseases and Injuries Among Children and Adolescents Between 1990 and 2013 | JAMA Pediatrics | 2016 | 479 |
| 7 | Metabolomics enables precision medicine: “A White Paper, Community Perspective” | Metabolomics | 2016 | 434 |
| 8 | Preferential transfer of mitochondria from endothelial to cancer cells through tunneling nanotubes modulates chemoresistance | Journal of Translational Medicine | 2013 | 359 |
| 9 | De novo genome sequencing and comparative genomics of date palm (Phoenix dactylifera) | Nature Biotechnology | 2011 | 356 |
| 10 | Halfway between 2D and Animal Models: Are 3D Cultures the Ideal Tool to Study Cancer-Microenvironment Interactions? | International Journal of Molecular Sciences | 2018 | 329 |
| 11 | Mutations in LRP2, which encodes the multiligand receptor megalin, cause Donnai-Barrow and facio-oculo-acoustico-renal syndromes | Nature Genetics | 2007 | 284 |
| 12 | Gender-specific pathway differences in the human serum metabolome | Metabolomics | 2015 | 218 |
| 13 | FGF21 Maintains Glucose Homeostasis by Mediating the Cross Talk Between Liver and Brain During Prolonged Fasting | Diabetes | 2014 | 217 |
| 14 | Associations among late chronotype, body mass index and dietary behaviors in young adolescents | International Journal of Obesity | 2015 | 196 |
| 15 | Metformin modulates hyperglycaemia‐induced endothelial senescence and apoptosis through SIRT1 | British Journal of Pharmacology | 2014 | 193 |
| 16 | The endothelium: influencing vascular smooth muscle in many ways | Canadian Journal of Physiology and Pharmacology | 2012 | 188 |
| 17 | Functional Network Pipeline Reveals Genetic Determinants Associated with in Situ Lymphocyte Proliferation and Survival of Cancer Patients | Science Translational Medicine | 2014 | 181 |
| 18 | Tunneling Nanotubes and Gap Junctions–Their Role in Long-Range Intercellular Communication during Development, Health, and Disease Conditions | Frontiers in Molecular Neuroscience | 2017 | 181 |
| 19 | Genetic variation in metabolic phenotypes: study designs and applications | Nature Reviews Genetics | 2012 | 165 |
| 20 | Whole genome re-sequencing of date palms yields insights into diversification of a fruit tree crop | Nature Communications | 2015 | 148 |
| 21 | Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | The Lancet Global Health | 2016 | 147 |
| 22 | Breast cancer in Arab populations: molecular characteristics and disease management implications | Lancet Oncology, The | 2013 | 145 |
| 23 | Novel MIR143‐NOTCH fusions in benign and malignant glomus tumors | Genes Chromosomes and Cancer | 2013 | 138 |
| 24 | Epigenetic silencing of microRNA-149 in cancer-associated fibroblasts mediates prostaglandin E2/interleukin-6 signaling in the tumor microenvironment | Cell Research | 2015 | 138 |
| 25 | Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies | Metabolomics | 2018 | 138 |
| 26 | Associations of circulating plasma microRNAs with age, body mass index and sex in a population-based study | BMC Medical Genomics | 2015 | 133 |
| 27 | Sleep Quality Prediction From Wearable Data Using Deep Learning | JMIR MHealth and UHealth | 2016 | 133 |
| 28 | Cancer Metabolism and Drug Resistance | Metabolites | 2015 | 130 |
| 29 | Mechanisms for the control of respiratory evaporative heat loss in panting animals | Journal of Applied Physiology | 2006 | 127 |
| 30 | European Society of Gynaecological Oncology (ESGO) Guidelines for Ovarian Cancer Surgery | International Journal of Gynecological Cancer | 2017 | 121 |
| 31 | Understanding fertilization through intracytoplasmic sperm injection (ICSI) | Cell Calcium | 2014 | 115 |
| 32 | Exercise Alleviates Obesity-Induced Metabolic Dysfunction via Enhancing FGF21 Sensitivity in Adipose Tissues | Cell Reports | 2019 | 115 |
| 33 | Reflections on a systematic nomenclature for antimicrobial peptides from the skins of frogs of the family Ranidae | Peptides | 2008 | 112 |
| 34 | Targeting Autocrine CCL5–CCR5 Axis Reprograms Immunosuppressive Myeloid Cells and Reinvigorates Antitumor Immunity | Cancer Research | 2017 | 111 |
| 35 | Population Genetic Structure of the People of Qatar | American Journal of Human Genetics | 2010 | 110 |
| 36 | Epigenetic associations of type 2 diabetes and BMI in an Arab population | Clinical Epigenetics | 2016 | 110 |
| 37 | Cyanotoxins in desert environments may present a risk to human health | Science of the Total Environment | 2012 | 109 |
| 38 | Constitutive recycling of the store-operated Ca2+ channel Orai1 and its internalization during meiosis | Journal of Cell Biology | 2010 | 108 |
| 39 | The Qatar genome: a population-specific tool for precision medicine in the Middle East | Human Genome Variation | 2016 | 103 |
| 40 | To the point: medical education review of the role of simulators in surgical training | American Journal of Obstetrics and Gynecology | 2008 | 101 |
| 41 | Endothelial Dysfunction in Diabetes Mellitus: Possible Involvement of Endoplasmic Reticulum Stress? | Experimental Diabetes Research | 2012 | 98 |
| 42 | A pilot study comparing the metabolic profiles of elite-level athletes from different sporting disciplines | Sports Medicine - Open | 2018 | 94 |
| 43 | The ER-Associated Degradation Adaptor Protein Sel1L Regulates LPL Secretion and Lipid Metabolism | Cell Metabolism | 2014 | 92 |
| 44 | The role of education in knowledge economies in developing countries | Procedia, Social and Behavioral Sciences | 2011 | 91 |
| 45 | Ovarian epithelial cancer: a role for PGE2-synthesis and signalling in malignant transformation and progression | Molecular Cancer | 2006 | 87 |
| 46 | Genome-wide identification and functional analysis of Apobec-1-mediated C-to-U RNA editing in mouse small intestine and liver | Genome Biology | 2014 | 87 |
| 47 | A review of endothelial dysfunction in diabetes: a focus on the contribution of a dysfunctional eNOS | Journal of the American Society of Hypertension | 2010 | 84 |
| 48 | Epithelial to Mesenchymal Transition in a Clinical Perspective | Journal of Oncology | 2015 | 84 |
| 49 | An immunologic portrait of cancer | Journal of Translational Medicine | 2011 | 83 |
| 50 | A first genetic map of date palm (Phoenix dactylifera) reveals long-range genome structure conservation in the palms | BMC Genomics | 2014 | 83 |
