| # | Title | Journal | Year | Citations |
|---|
| 1 | 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides | Arthritis and Rheumatism | 2013 | 4,839 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 3 | Diagnosis of multiple sclerosis: 2017 revisions of the McDonald criteria | Lancet Neurology, The | 2018 | 4,605 |
| 4 | A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease | Nature | 2001 | 4,589 |
| 5 | Effect of Rosiglitazone on the Risk of Myocardial Infarction and Death from Cardiovascular Causes | New England Journal of Medicine | 2007 | 4,356 |
| 6 | Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease | Nature | 2011 | 4,238 |
| 7 | Neuroinflammation in Alzheimer's disease | Lancet Neurology, The | 2015 | 4,129 |
| 8 | Definition and classification of cancer cachexia: an international consensus | Lancet Oncology, The | 2011 | 4,015 |
| 9 | Comparison of Two Fluid-Management Strategies in Acute Lung Injury | New England Journal of Medicine | 2006 | 3,821 |
| 10 | Recommendations for the Evaluation of Left Ventricular Diastolic Function by Echocardiography: An Update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging | Journal of the American Society of Echocardiography | 2016 | 3,807 |
| 11 | Axonal Transection in the Lesions of Multiple Sclerosis | New England Journal of Medicine | 1998 | 3,776 |
| 12 | HOW CELLS RESPOND TO INTERFERONS | Annual Review of Biochemistry | 1998 | 3,630 |
| 13 | Assessing the Performance of Prediction Models | Epidemiology | 2010 | 3,387 |
| 14 | Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis | Nature Medicine | 2013 | 3,355 |
| 15 | Oxidative Stress and Antioxidant Defense | World Allergy Organization Journal | 2012 | 3,353 |
| 16 | IL-33, an Interleukin-1-like Cytokine that Signals via the IL-1 Receptor-Related Protein ST2 and Induces T Helper Type 2-Associated Cytokines | Immunity | 2005 | 3,161 |
| 17 | Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors | Nature | 2020 | 3,133 |
| 18 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 19 | Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial | Lancet, The | 2016 | 3,077 |
| 20 | Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner | Neuron | 2012 | 3,040 |
| 21 | Biomechanical Measures of Neuromuscular Control and Valgus Loading of the Knee Predict Anterior Cruciate Ligament Injury Risk in Female Athletes: A Prospective Study | American Journal of Sports Medicine | 2005 | 3,022 |
| 22 | The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2018 update | Nucleic Acids Research | 2018 | 3,003 |
| 23 | Intra-arterial Prourokinase for Acute Ischemic Stroke | JAMA - Journal of the American Medical Association | 1999 | 2,784 |
| 24 | A clinical approach to diagnosis of autoimmune encephalitis | Lancet Neurology, The | 2016 | 2,782 |
| 25 | Protected Carotid-Artery Stenting versus Endarterectomy in High-Risk Patients | New England Journal of Medicine | 2004 | 2,729 |
| 26 | Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 | Journal of the American College of Cardiology | 2017 | 2,705 |
| 27 | Toward discovery science of human brain function | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 2,703 |
| 28 | Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria | Lancet Neurology, The | 2014 | 2,657 |
| 29 | Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events | New England Journal of Medicine | 2006 | 2,582 |
| 30 | Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk | New England Journal of Medicine | 2013 | 2,537 |
| 31 | Revised International Prognostic Scoring System for Myelodysplastic Syndromes | Blood | 2012 | 2,458 |
| 32 | Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis | Annals of Neurology | 1996 | 2,365 |
| 33 | The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma | American Journal of Surgical Pathology | 2005 | 2,334 |
| 34 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 35 | Magnetic Resonance Imaging of the Lumbar Spine in People without Back Pain | New England Journal of Medicine | 1994 | 2,128 |
| 36 | Chemohormonal Therapy in Metastatic Hormone-Sensitive Prostate Cancer | New England Journal of Medicine | 2015 | 2,112 |
| 37 | The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis | Arthritis and Rheumatism | 1990 | 2,068 |
| 38 | Identification of a unique TGF-β–dependent molecular and functional signature in microglia | Nature Neuroscience | 2014 | 2,056 |
| 39 | A comprehensive 1000 Genomes–based genome-wide association meta-analysis of coronary artery disease | Nature Genetics | 2015 | 2,054 |
| 40 | Oral Fingolimod or Intramuscular Interferon for Relapsing Multiple Sclerosis | New England Journal of Medicine | 2010 | 1,983 |
| 41 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 42 | The Voice Handicap Index (VHI) | American Journal of Speech-Language Pathology | 1997 | 1,942 |
| 43 | A Clinical Score to Predict Acute Renal Failure after Cardiac Surgery | Journal of the American Society of Nephrology: JASN | 2005 | 1,917 |
| 44 | The Role of Stress Echocardiography in Valvular Heart Disease: A Current Appraisal | Cardiology | 2017 | 1,908 |
| 45 | Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial | Lancet, The | 2015 | 1,840 |
| 46 | The American College of Rheumatology 1990 criteria for the classification of churg‐strauss syndrome (allergic granulomatosis and angiitis) | Arthritis and Rheumatism | 1990 | 1,838 |
| 47 | Dual-Chamber Pacing or Ventricular Backup Pacing in Patients With an Implantable Defibrillator | JAMA - Journal of the American Medical Association | 2002 | 1,799 |
| 48 | The American College of Rheumatology 1990 criteria for the classification of takayasu arteritis | Arthritis and Rheumatism | 1990 | 1,799 |
| 49 | Platelet Glycoprotein IIb/IIIa Receptor Blockade and Low-Dose Heparin during Percutaneous Coronary Revascularization | New England Journal of Medicine | 1997 | 1,797 |
| 50 | Clinical Practice Guideline for Diagnostic Testing for Adult Obstructive Sleep Apnea: An American Academy of Sleep Medicine Clinical Practice Guideline | Journal of Clinical Sleep Medicine | 2017 | 1,783 |
