| Central role for G protein-coupled phosphoinositide 3-kinase gamma in inflammation | Science | 2000 | 1.1K |
| Practice guidelines developed by specialty societies: the need for a critical appraisal | Lancet, The | 2000 | 516 |
| Inflammatory cytokines and related genes are induced in the rat hippocampus by limbic status epilepticus | European Journal of Neuroscience | 2000 | 378 |
| Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in mice | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 368 |
| Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages | Journal of Immunology | 2000 | 358 |
| PTX3, A prototypical long pentraxin, is an early indicator of acute myocardial infarction in humans | Circulation | 2000 | 345 |
| Interaction of junctional adhesion molecule with the tight junction components ZO-1, cingulin, and occludin | Journal of Biological Chemistry | 2000 | 332 |
| Endothelin-1 induces an angiogenic phenotype in cultured endothelial cells and stimulates neovascularization in vivo | American Journal of Pathology | 2000 | 285 |
| Correlative light-electron microscopy reveals the tubular-saccular ultrastructure of carriers operating between Golgi apparatus and plasma membrane | Journal of Cell Biology | 2000 | 276 |
| Myocyte death in streptozotocin-induced diabetes in rats in angiotensin II- dependent | Laboratory Investigation | 2000 | 262 |
| Strategies for making more organs available for transplantation | New England Journal of Medicine | 2000 | 239 |
| Uncoupling of inflammatory chemokine receptors by IL-10: generation of functional decoys | Nature Immunology | 2000 | 215 |
| Diet diversity and colorectal cancer | Preventive Medicine | 2000 | 191 |
| Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743 | Proceedings of the National Academy of Sciences of the United States of America | 2000 | 176 |
| Preferential modulation of mesolimbic vs. nigrostriatal dopaminergic function by serotonin(2C/2B) receptor agonists: a combined in vivo electrophysiological and microdialysis study | Synapse | 2000 | 148 |
| Chronic proteinuric nephropathies: outcomes and response to treatment in a prospective cohort of 352 patients with different patterns of renal injury | American Journal of Kidney Diseases | 2000 | 147 |
| Oral hygiene, dentition, sexual habits and risk of oral cancer | British Journal of Cancer | 2000 | 144 |
| Food groups and risk of squamous cell esophageal cancer in Northern Italy | International Journal of Cancer | 2000 | 143 |
| The heparin binding 25 kDa fragment of thrombospondin-1 promotes angiogenesis and modulates gelatinase and TIMP-2 production in endothelial cells | FASEB Journal | 2000 | 137 |
| Protein traffic activates NF-kB gene signaling and promotes MCP-1-dependent interstitial inflammation | American Journal of Kidney Diseases | 2000 | 134 |
| Red meat intake and cancer risk: a study in Italy | International Journal of Cancer | 2000 | 132 |
| The chemokine receptor switch paradigm and dendritic cell migration: its significance in tumor tissues | Immunological Reviews | 2000 | 129 |
| Clinical effects of early angiotensin-converting enzyme inhibitor treatment for acute myocardial infarction are similar in the presence and absence of aspirin: systematic overview of individual data from 96,712 randomized patients. Angiotensin-converting Enzyme Inhibitor Myocardial Infarction Collaborative Group | Journal of the American College of Cardiology | 2000 | 129 |
| Chemokines and dendritic cell traffic | Journal of Clinical Immunology | 2000 | 125 |
| Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma | Journal of Immunology | 2000 | 121 |
