| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,789 |
| 3 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 | Cell Death and Differentiation | 2018 | 4,451 |
| 4 | In Silico Detection and Typing of Plasmids using PlasmidFinder and Plasmid Multilocus Sequence Typing | Antimicrobial Agents and Chemotherapy | 2014 | 3,815 |
| 5 | Identification and expansion of human colon-cancer-initiating cells | Nature | 2007 | 3,737 |
| 6 | Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy | JAMA - Journal of the American Medical Association | 2020 | 3,321 |
| 7 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,158 |
| 9 | Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009 | Cell Death and Differentiation | 2009 | 2,613 |
| 10 | Extending Healthy Life Span—From Yeast to Humans | Science | 2010 | 2,558 |
| 11 | Social Contacts and Mixing Patterns Relevant to the Spread of Infectious Diseases | PLoS Medicine | 2008 | 2,438 |
| 12 | Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 | Cell Death and Differentiation | 2012 | 2,182 |
| 13 | Identification of plasmids by PCR-based replicon typing | Journal of Microbiological Methods | 2005 | 2,166 |
| 14 | Liposomes as nanomedical devices | International Journal of Nanomedicine | 2015 | 1,664 |
| 15 | Cancer survival in Europe 1999–2007 by country and age: results of EUROCARE-5—a population-based study | Lancet Oncology, The | 2014 | 1,595 |
| 16 | Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome | Nature Genetics | 2001 | 1,575 |
| 17 | Identification and expansion of the tumorigenic lung cancer stem cell population | Cell Death and Differentiation | 2008 | 1,527 |
| 18 | QSAR Modeling: Where Have You Been? Where Are You Going To? | Journal of Medicinal Chemistry | 2014 | 1,475 |
| 19 | Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies | BMJ: British Medical Journal | 2005 | 1,328 |
| 20 | Infection with chikungunya virus in Italy: an outbreak in a temperate region | Lancet, The | 2007 | 1,295 |
| 21 | Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells | Nature | 2010 | 1,258 |
| 22 | Microenvironmental pH Is a Key Factor for Exosome Traffic in Tumor Cells | Journal of Biological Chemistry | 2009 | 1,250 |
| 23 | Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology | Brain | 2006 | 1,188 |
| 24 | The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics | Cell Biology and Toxicology | 2005 | 1,142 |
| 25 | Immune function of microglia | Glia | 2001 | 1,136 |
| 26 | Astrocytes are active players in cerebral innate immunity | Trends in Immunology | 2007 | 1,136 |
| 27 | Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA–Peptide Complexes in Systemic Lupus Erythematosus | Science Translational Medicine | 2011 | 1,112 |
| 28 | Resistance Plasmid Families in Enterobacteriaceae | Antimicrobial Agents and Chemotherapy | 2009 | 1,088 |
| 29 | Cancer survival in five continents: a worldwide population-based study (CONCORD) | Lancet Oncology, The | 2008 | 1,081 |
| 30 | Detection of Ectopic B‐cell Follicles with Germinal Centers in the Meninges of Patients with Secondary Progressive Multiple Sclerosis | Brain Pathology | 2004 | 1,043 |
| 31 | Fusion proteins of the retinoic acid receptor-α recruit histone deacetylase in promyelocytic leukaemia | Nature | 1998 | 1,017 |
| 32 | Somatic mutations in PTPN11 in juvenile myelomonocytic leukemia, myelodysplastic syndromes and acute myeloid leukemia | Nature Genetics | 2003 | 973 |
| 33 | Sex and Gender Equity in Research: rationale for the SAGER guidelines and recommended use | Research Integrity and Peer Review | 2016 | 933 |
| 34 | Risk thresholds for alcohol consumption: combined analysis of individual-participant data for 599 912 current drinkers in 83 prospective studies | Lancet, The | 2018 | 915 |
| 35 | Type I Interferons Potently Enhance Humoral Immunity and Can Promote Isotype Switching by Stimulating Dendritic Cells In Vivo | Immunity | 2001 | 877 |
| 36 | Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy | Nature Medicine | 2014 | 869 |
| 37 | Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes | Journal of Nutritional Biochemistry | 2005 | 855 |
| 38 | Uniformity of rotavirus strain nomenclature proposed by the Rotavirus Classification Working Group (RCWG) | Archives of Virology | 2011 | 850 |
| 39 | An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans | Carcinogenesis | 2006 | 842 |
| 40 | Childhood cancer survival in Europe 1999–2007: results of EUROCARE-5—a population-based study | Lancet Oncology, The | 2014 | 835 |
| 41 | Klebsiella pneumoniae: a major worldwide source and shuttle for antibiotic resistance | FEMS Microbiology Reviews | 2017 | 834 |
| 42 | Lymphoid neogenesis in chronic inflammatory diseases | Nature Reviews Immunology | 2006 | 833 |
| 43 | High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients | PLoS ONE | 2009 | 831 |
| 44 | Recent cancer survival in Europe: a 2000–02 period analysis of EUROCARE-4 data | Lancet Oncology, The | 2007 | 823 |
| 45 | Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 810 |
| 46 | Incidence of hematologic malignancies in Europe by morphologic subtype: results of the HAEMACARE project | Blood | 2010 | 809 |
| 47 | Plasmids and the spread of resistance | International Journal of Medical Microbiology | 2013 | 797 |
| 48 | THE NERVE GROWTH FACTOR: PURIFICATION AS A 30,000-MOLECULAR-WEIGHT PROTEIN | Proceedings of the National Academy of Sciences of the United States of America | 1969 | 792 |
| 49 | Immune-based mechanisms of cytotoxic chemotherapy: implications for the design of novel and rationale-based combined treatments against cancer | Cell Death and Differentiation | 2014 | 767 |
| 50 | MicroRNAs 221 and 222 inhibit normal erythropoiesis and erythroleukemic cell growth via kit receptor down-modulation | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 753 |
