| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia | Brain | 2011 | 3,913 |
| 3 | Release of chromatin protein HMGB1 by necrotic cells triggers inflammation | Nature | 2002 | 3,748 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 5 | Defining the clinical course of multiple sclerosis | Neurology | 2014 | 2,344 |
| 6 | Clinical Targets for Continuous Glucose Monitoring Data Interpretation: Recommendations From the International Consensus on Time in Range | Diabetes Care | 2019 | 2,101 |
| 7 | Shedding microvesicles: artefacts no more | Trends in Cell Biology | 2009 | 1,559 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 9 | Ibrutinib versus Ofatumumab in Previously Treated Chronic Lymphoid Leukemia | New England Journal of Medicine | 2014 | 1,427 |
| 10 | uPAR: a versatile signalling orchestrator | Nature Reviews Molecular Cell Biology | 2002 | 1,140 |
| 11 | Anxiety and depression in COVID-19 survivors: Role of inflammatory and clinical predictors | Brain, Behavior, and Immunity | 2020 | 1,118 |
| 12 | Correction of ADA-SCID by Stem Cell Gene Therapy Combined with Nonmyeloablative Conditioning | Science | 2002 | 1,081 |
| 13 | iwCLL guidelines for diagnosis, indications for treatment, response assessment, and supportive management of CLL | Blood | 2018 | 1,069 |
| 14 | Restless Legs Syndrome Prevalence and Impact | Archives of Internal Medicine | 2005 | 1,046 |
| 15 | Lentiviral Hematopoietic Stem Cell Gene Therapy Benefits Metachromatic Leukodystrophy | Science | 2013 | 998 |
| 16 | Systematic Review and Meta-analysis of Studies Reporting Urinary Continence Recovery After Robot-assisted Radical Prostatectomy | European Urology | 2012 | 961 |
| 17 | Monocyte-derived IL-1 and IL-6 are differentially required for cytokine-release syndrome and neurotoxicity due to CAR T cells | Nature Medicine | 2018 | 947 |
| 18 | Listening to Action-related Sentences Activates Fronto-parietal Motor Circuits | Journal of Cognitive Neuroscience | 2005 | 925 |
| 19 | Lentiviral Hematopoietic Stem Cell Gene Therapy in Patients with Wiskott-Aldrich Syndrome | Science | 2013 | 900 |
| 20 | Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study | Lancet Rheumatology, The | 2020 | 808 |
| 21 | Multiple sclerosis | Nature Reviews Disease Primers | 2018 | 767 |
| 22 | Renal cancer | Lancet, The | 2016 | 762 |
| 23 | Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production | International Immunology | 2007 | 756 |
| 24 | Effects of levosimendan on mortality and hospitalization. A meta-analysis of randomized controlled studies* | Critical Care Medicine | 2012 | 734 |
| 25 | Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells | Nature Medicine | 2013 | 700 |
| 26 | MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines | Lancet Neurology, The | 2016 | 679 |
| 27 | Rates and Patterns of Recurrence Following Curative Intent Surgery for Colorectal Liver Metastasis | Annals of Surgery | 2009 | 664 |
| 28 | Rapamycin Promotes Expansion of Functional CD4+CD25+FOXP3+ Regulatory T Cells of Both Healthy Subjects and Type 1 Diabetic Patients | Journal of Immunology | 2006 | 643 |
| 29 | Safety and efficacy of raltegravir-based versus efavirenz-based combination therapy in treatment-naive patients with HIV-1 infection: a multicentre, double-blind randomised controlled trial | Lancet, The | 2009 | 621 |
| 30 | Systematic Review and Meta-analysis of Studies Reporting Potency Rates After Robot-assisted Radical Prostatectomy | European Urology | 2012 | 620 |
| 31 | Intrahepatic Cholangiocarcinoma: An International Multi-Institutional Analysis of Prognostic Factors and Lymph Node Assessment | Journal of Clinical Oncology | 2011 | 615 |
| 32 | Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions | Endocrine Reviews | 2019 | 611 |
| 33 | The logopenic/phonological variant of primary progressive aphasia | Neurology | 2008 | 602 |
| 34 | Impact, diagnosis and treatment of restless legs syndrome (RLS) in a primary care population: the REST (RLS epidemiology, symptoms, and treatment) primary care study | Sleep Medicine | 2004 | 588 |
| 35 | Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture | Nature Genetics | 2013 | 578 |
| 36 | Cardiac Index Validation Using the Pressure Recording Analytic Method in Unstable Patients | Journal of Cardiothoracic and Vascular Anesthesia | 2010 | 572 |
| 37 | Long-term remissions after FCR chemoimmunotherapy in previously untreated patients with CLL: updated results of the CLL8 trial | Blood | 2016 | 571 |
| 38 | Differential diagnosis of suspected multiple sclerosis: a consensus approach | Multiple Sclerosis Journal | 2008 | 560 |
| 39 | Safety and recommendations for TMS use in healthy subjects and patient populations, with updates on training, ethical and regulatory issues: Expert Guidelines | Clinical Neurophysiology | 2021 | 553 |
| 40 | Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state | Nature Biotechnology | 2007 | 539 |
| 41 | Efficacy of the BNT162b2 mRNA COVID-19 vaccine in patients with chronic lymphocytic leukemia | Blood | 2021 | 539 |
| 42 | Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner | Immunity | 2011 | 529 |
| 43 | Ischemia and No Obstructive Coronary Artery Disease (INOCA) | Circulation | 2017 | 527 |
| 44 | Prophylaxis of post-ERCP pancreatitis: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Updated June 2014 | Endoscopy | 2014 | 521 |
| 45 | The International Consensus Classification of Mature Lymphoid Neoplasms: a report from the Clinical Advisory Committee | Blood | 2022 | 512 |
| 46 | The Psychological Impact of Epidemic and Pandemic Outbreaks on Healthcare Workers: Rapid Review of the Evidence | Current Psychiatry Reports | 2020 | 509 |
| 47 | Efficacy and safety of darunavir-ritonavir at week 48 in treatment-experienced patients with HIV-1 infection in POWER 1 and 2: a pooled subgroup analysis of data from two randomised trials | Lancet, The | 2007 | 506 |
| 48 | Resting state fMRI in Alzheimer's disease: beyond the default mode network | Neurobiology of Aging | 2012 | 497 |
| 49 | The Serine Protease Matriptase-2 (TMPRSS6) Inhibits Hepcidin Activation by Cleaving Membrane Hemojuvelin | Cell Metabolism | 2008 | 494 |
| 50 | The genotoxic potential of retroviral vectors is strongly modulated by vector design and integration site selection in a mouse model of HSC gene therapy | Journal of Clinical Investigation | 2009 | 488 |
