| # | Title | Journal | Year | Citations |
|---|
| 1 | Dementia prevention, intervention, and care: 2020 report of the Lancet Commission | Lancet, The | 2020 | 4,658 |
| 2 | Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 | Intensive Care Medicine | 2017 | 4,590 |
| 3 | Neural systems supporting interoceptive awareness | Nature Neuroscience | 2004 | 2,955 |
| 4 | Consensus statement on the pathology of IgG4-related disease | Modern Pathology | 2012 | 2,171 |
| 5 | Cross-national prevalence and risk factors for suicidal ideation, plans and attempts | British Journal of Psychiatry | 2008 | 1,993 |
| 6 | Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys | British Journal of Psychiatry | 2010 | 1,854 |
| 7 | Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials | Blood | 2010 | 1,661 |
| 8 | Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer | New England Journal of Medicine | 2020 | 1,513 |
| 9 | Global and regional effects of potentially modifiable risk factors associated with acute stroke in 32 countries (INTERSTROKE): a case-control study | Lancet, The | 2016 | 1,414 |
| 10 | British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults | Gut | 2019 | 1,353 |
| 11 | Estimating the global incidence of traumatic brain injury | Journal of Neurosurgery | 2019 | 1,291 |
| 12 | Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution | Nature | 2017 | 1,287 |
| 13 | Use of mental health services for anxiety, mood, and substance disorders in 17 countries in the WHO world mental health surveys | Lancet, The | 2007 | 1,271 |
| 14 | Persistent Pain and Well-being | JAMA - Journal of the American Medical Association | 1998 | 1,252 |
| 15 | Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome | Intensive Care Medicine | 2013 | 1,197 |
| 16 | A Method for Removing Imaging Artifact from Continuous EEG Recorded during Functional MRI | NeuroImage | 2000 | 1,170 |
| 17 | Guidelines for the management of inflammatory bowel disease in adults | Gut | 2011 | 1,127 |
| 18 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study | Lancet Infectious Diseases, The | 2010 | 1,107 |
| 19 | Neural mechanisms of autonomic, affective, and cognitive integration | Journal of Comparative Neurology | 2005 | 1,042 |
| 20 | Aggressive conventional chemotherapy compared with high-dose chemotherapy with autologous haemopoietic stem-cell transplantation for relapsed chemosensitive Hodgkin's disease: a randomised trial | Lancet, The | 2002 | 1,016 |
| 21 | Systematic review and evaluation of physiological track and trigger warning systems for identifying at-risk patients on the ward | Intensive Care Medicine | 2007 | 962 |
| 22 | Spatial and temporal diversity in genomic instability processes defines lung cancer evolution | Science | 2014 | 962 |
| 23 | Alzheimer's disease and vascular dementia in developing countries: prevalence, management, and risk factors | Lancet Neurology, The | 2008 | 960 |
| 24 | Screening for serious mental illness in the general population with the K6 screening scale: results from the WHO World Mental Health (WMH) survey initiative | International Journal of Methods in Psychiatric Research | 2010 | 953 |
| 25 | Common Chronic Pain Conditions in Developed and Developing Countries: Gender and Age Differences and Comorbidity With Depression-Anxiety Disorders | Journal of Pain | 2008 | 918 |
| 26 | Mental disorders among college students in the World Health Organization World Mental Health Surveys | Psychological Medicine | 2016 | 866 |
| 27 | Doxorubicin alone versus intensified doxorubicin plus ifosfamide for first-line treatment of advanced or metastatic soft-tissue sarcoma: a randomised controlled phase 3 trial | Lancet Oncology, The | 2014 | 864 |
| 28 | Mipomersen, an apolipoprotein B synthesis inhibitor, for lowering of LDL cholesterol concentrations in patients with homozygous familial hypercholesterolaemia: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2010 | 813 |
| 29 | Effect of Nivolumab vs Bevacizumab in Patients With Recurrent Glioblastoma | JAMA Oncology | 2020 | 805 |
| 30 | Trauma and PTSD in the WHO World Mental Health Surveys | Högre Utbildning | 2017 | 801 |
| 31 | Understanding Patients’ Adherence-Related Beliefs about Medicines Prescribed for Long-Term Conditions: A Meta-Analytic Review of the Necessity-Concerns Framework | PLoS ONE | 2013 | 799 |
| 32 | The epidemiology of traumatic event exposure worldwide: results from the World Mental Health Survey Consortium | Psychological Medicine | 2016 | 777 |
| 33 | The Analgesic Efficacy of Transversus Abdominis Plane Block After Abdominal Surgery: A Prospective Randomized Controlled Trial | Anesthesia and Analgesia | 2007 | 746 |
| 34 | Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity | Nature | 2017 | 743 |
| 35 | Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from the TARGIT-A randomised trial | Lancet, The | 2014 | 740 |
| 36 | Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) | Lancet Oncology, The | 2009 | 738 |
| 37 | Outcome of 609 adults after relapse of acute lymphoblastic leukemia (ALL); an MRC UKALL12/ECOG 2993 study | Blood | 2007 | 716 |
| 38 | The Systemic Inflammatory Response to Cardiac Surgery | Anesthesiology | 2002 | 709 |
| 39 | In adults with standard-risk acute lymphoblastic leukemia, the greatest benefit is achieved from a matched sibling allogeneic transplantation in first complete remission, and an autologous transplantation is less effective than conventional consolidation/maintenance chemotherapy in all patients: final results of the International ALL Trial (MRC UKALL XII/ECOG E2993) | Blood | 2008 | 702 |
| 40 | Targeted intraoperative radiotherapy versus whole breast radiotherapy for breast cancer (TARGIT-A trial): an international, prospective, randomised, non-inferiority phase 3 trial | Lancet, The | 2010 | 677 |
| 41 | Posttraumatic stress disorder in the World Mental Health Surveys | Psychological Medicine | 2017 | 675 |
| 42 | Intraoperative intravascular volume optimisation and length of hospital stay after repair of proximal femoral fracture: randomised controlled trial | BMJ: British Medical Journal | 1997 | 674 |
| 43 | Congenital Adrenal Hyperplasia Due to Steroid 21-Hydroxylase Deficiency: An Endocrine Society* Clinical Practice Guideline | Journal of Clinical Endocrinology and Metabolism | 2018 | 667 |
| 44 | Undertreatment of people with major depressive disorder in 21 countries | British Journal of Psychiatry | 2017 | 664 |
| 45 | Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease | Journal of the American College of Cardiology | 2015 | 662 |
| 46 | A clinically applicable approach to continuous prediction of future acute kidney injury | Nature | 2019 | 652 |
| 47 | EULAR recommendations for the management of systemic lupus erythematosus. Report of a Task Force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics | Annals of the Rheumatic Diseases | 2008 | 645 |
| 48 | Randomised trial of filgrastim-mobilised peripheral blood progenitor cell transplantation versus autologous bone-marrow transplantation in lymphoma patients | Lancet, The | 1996 | 641 |
| 49 | Soft tissue and visceral sarcomas: ESMO–EURACAN Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2018 | 641 |
| 50 | Toward a Global View of Alcohol, Tobacco, Cannabis, and Cocaine Use: Findings from the WHO World Mental Health Surveys | PLoS Medicine | 2008 | 629 |
