| # | Title | Journal | Year | Citations |
|---|
| 1 | Frontotemporal lobar degeneration | Neurology | 1998 | 4,852 |
| 2 | Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial | Lancet, The | 2004 | 3,502 |
| 3 | Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17 | Nature | 1998 | 3,333 |
| 4 | International consensus report on the investigation and management of primary immune thrombocytopenia | Blood | 2010 | 1,802 |
| 5 | Determinants of pulse wave velocity in healthy people and in the presence of cardiovascular risk factors: ‘establishing normal and reference values’ | European Heart Journal | 2010 | 1,637 |
| 6 | Diabetic Neuropathies: A statement by the American Diabetes Association | Diabetes Care | 2005 | 1,599 |
| 7 | Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial | Lancet, The | 2017 | 1,475 |
| 8 | A multicentre study of the prevalence of diabetic peripheral neuropathy in the United Kingdom hospital clinic population | Diabetologia | 1993 | 1,286 |
| 9 | Coagulation abnormalities and thrombosis in patients with COVID-19 | Lancet Haematology,the | 2020 | 1,186 |
| 10 | The prevalence of food allergy: A meta-analysis | Journal of Allergy and Clinical Immunology | 2007 | 1,124 |
| 11 | Mutations of the Cystic Fibrosis Gene in Patients with Chronic Pancreatitis | New England Journal of Medicine | 1998 | 933 |
| 12 | The North-West Diabetes Foot Care Study: incidence of, and risk factors for, new diabetic foot ulceration in a community-based patient cohort | Diabetic Medicine | 2002 | 870 |
| 13 | 5-HT and mechanisms of defence | Journal of Psychopharmacology | 1991 | 868 |
| 14 | Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein | FEBS Letters | 1991 | 847 |
| 15 | Hypothalamic-Pituitary-Testicular Axis Disruptions in Older Men Are Differentially Linked to Age and Modifiable Risk Factors: The European Male Aging Study | Journal of Clinical Endocrinology and Metabolism | 2008 | 790 |
| 16 | Diabetic Somatic Neuropathies | Diabetes Care | 2004 | 756 |
| 17 | Protection of low-density lipoprotein against oxidative modification by high-density lipoprotein associated paraoxonase | Atherosclerosis | 1993 | 737 |
| 18 | Guidelines for the management of adult lower respiratory tract infections - Full version | Clinical Microbiology and Infection | 2011 | 721 |
| 19 | Paraoxonase and Atherosclerosis | Arteriosclerosis, Thrombosis, and Vascular Biology | 2001 | 715 |
| 20 | Systematic review of carbohydrate antigen (CA 19-9) as a biochemical marker in the diagnosis of pancreatic cancer | European Journal of Surgical Oncology | 2007 | 705 |
| 21 | Towards a standardised brief outcome measure: Psychometric properties and utility of the CORE–OM | British Journal of Psychiatry | 2002 | 679 |
| 22 | Peripheral Arterial Disease in Diabetic and Nondiabetic Patients: A comparison of severity and outcome | Diabetes Care | 2001 | 658 |
| 23 | Matrix metalloproteinase and proinflammatory cytokine production by chondrocytes of human osteoarthritic cartilage: Associations with degenerative changes | Arthritis and Rheumatism | 2001 | 655 |
| 24 | LMNA, encoding lamin A/C, is mutated in partial lipodystrophy | Nature Genetics | 2000 | 653 |
| 25 | MULTICENTER RANDOMIZED TRIAL COMPARING TACROLIMUS (FK506) AND CYCLOSPORINE IN THE PREVENTION OF RENAL ALLOGRAFT REJECTION1 | Transplantation | 1997 | 652 |
| 26 | Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation | Blood | 2007 | 646 |
| 27 | Towards evidence-based medicine in cardiothoracic surgery: best BETS | Interactive Cardiovascular and Thoracic Surgery | 2003 | 640 |
| 28 | Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma | Nature Genetics | 2014 | 624 |
| 29 | The risk of foot ulceration in diabetic patients with high foot pressure: a prospective study | Diabetologia | 1992 | 614 |
| 30 | Effects of Testosterone on Muscle Strength, Physical Function, Body Composition, and Quality of Life in Intermediate-Frail and Frail Elderly Men: A Randomized, Double-Blind, Placebo-Controlled Study | Journal of Clinical Endocrinology and Metabolism | 2010 | 556 |
| 31 | Effectiveness of meningococcal serogroup C conjugate vaccine 4 years after introduction | Lancet, The | 2004 | 549 |
| 32 | Survival, morbidity, and quality of life after discharge from intensive care | Critical Care Medicine | 2000 | 536 |
| 33 | The rare coagulation disorders - review with guidelines for management from the United Kingdom Haemophilia Centre Doctors' Organisation | Haemophilia | 2004 | 516 |
| 34 | Dementia of frontal lobe type. | Journal of Neurology, Neurosurgery and Psychiatry | 1988 | 498 |
| 35 | Distinct behavioural profiles in frontotemporal dementia and semantic dementia | Journal of Neurology, Neurosurgery and Psychiatry | 2001 | 495 |
| 36 | British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD) | Thorax | 2017 | 488 |
| 37 | Guidelines for the diagnosis and management of aplastic anaemia | British Journal of Haematology | 2009 | 487 |
| 38 | Characteristics of Secondary, Primary, and Compensated Hypogonadism in Aging Men: Evidence from the European Male Ageing Study | Journal of Clinical Endocrinology and Metabolism | 2010 | 481 |
| 39 | A Comparison of Two Diabetic Foot Ulcer Classification Systems: The Wagner and the University of Texas wound classification systems | Diabetes Care | 2001 | 466 |
| 40 | Neuroendocrine tumor epidemiology | Cancer | 2008 | 464 |
| 41 | Mortality rates, life expectancy, and causes of death in people with hemophilia A or B in the United Kingdom who were not infected with HIV | Blood | 2007 | 461 |
| 42 | Further fatal allergic reactions to food in the United Kingdom, 1999-2006 | Journal of Allergy and Clinical Immunology | 2007 | 460 |
| 43 | Surrogate Markers of Small Fiber Damage in Human Diabetic Neuropathy | Diabetes | 2007 | 455 |
| 44 | Coagulopathy in COVID‐19 | Journal of Thrombosis and Haemostasis | 2020 | 453 |
| 45 | Randomized Trial of C5a Receptor Inhibitor Avacopan in ANCA-Associated Vasculitis | Journal of the American Society of Nephrology: JASN | 2017 | 448 |
| 46 | A controlled trial of psychological treatment for the irritable bowel syndrome | Gastroenterology | 1991 | 446 |
| 47 | Chronic pancreatitis | Lancet, The | 2011 | 445 |
| 48 | Bronchopulmonary neuroendocrine tumors | Cancer | 2008 | 439 |
| 49 | Corneal confocal microscopy: a non-invasive surrogate of nerve fibre damage and repair in diabetic patients | Diabetologia | 2003 | 437 |
| 50 | Diabetic Foot Syndrome: Evaluating the prevalence and incidence of foot pathology in Mexican Americans and non-Hispanic whites from a diabetes disease management cohort | Diabetes Care | 2003 | 437 |
