| # | Title | Journal | Year | Citations |
|---|
| 1 | Vaginal Cytology of the Laboratory Rat and Mouse | Toxicologic Pathology | 2015 | 566 |
| 2 | Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Review | Environmental Health Perspectives | 2012 | 514 |
| 3 | Development of a testing battery to assess chemical-induced immunotoxicity: National toxicology program's guidelines for immunotoxicity evaluation in mice | Fundamental and Applied Toxicology | 1988 | 513 |
| 4 | The concordance between RNA-seq and microarray data depends on chemical treatment and transcript abundance | Nature Biotechnology | 2014 | 420 |
| 5 | Evaluation of nanoparticle immunotoxicity | Nature Nanotechnology | 2009 | 345 |
| 6 | Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers? | Environmental Science and Technology Letters | 2019 | 343 |
| 7 | Methods for assessing sperm motility, morphology, and counts in the rat, rabbit, and dog: A consensus report | Reproductive Toxicology | 1996 | 325 |
| 8 | Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review | Environmental Health Perspectives | 2012 | 299 |
| 9 | A Mouse Model of Chikungunya Virus–Induced Musculoskeletal Inflammatory Disease | American Journal of Pathology | 2011 | 245 |
| 10 | The Effects of Perinatal/Juvenile Methoxychlor Exposure on Adult Rat Nervous, Immune, and Reproductive System Function, | Fundamental and Applied Toxicology | 1997 | 244 |
| 11 | Arsenic and Environmental Health: State of the Science and Future Research Opportunities | Environmental Health Perspectives | 2016 | 235 |
| 12 | Compound Cytotoxicity Profiling Using Quantitative High-Throughput Screening | Environmental Health Perspectives | 2008 | 232 |
| 13 | Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model | Environmental Science & Technology | 2015 | 224 |
| 14 | Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress | Environmental Health Perspectives | 2014 | 221 |
| 15 | Toxicity Testing in the 21st Century: Implications for Human Health Risk Assessment | Risk Analysis | 2009 | 197 |
| 16 | Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study | Critical Reviews in Toxicology | 2014 | 191 |
| 17 | The developmental toxicity of bisphenol A in rats and mice*1 | Fundamental and Applied Toxicology | 1987 | 188 |
| 18 | Role of alpha‐1 antitrypsin in human health and disease | Journal of Internal Medicine | 2014 | 182 |
| 19 | Bisphenol A, Bisphenol S, and 4-Hydroxyphenyl 4-Isoprooxyphenylsulfone (BPSIP) in Urine and Blood of Cashiers | Environmental Health Perspectives | 2016 | 169 |
| 20 | Markers of Inflammation | Methods in Molecular Biology | 2018 | 163 |
| 21 | Prevalence of α1-antitrypsin deficiency alleles PI*S and PI*Z worldwide and effective screening for each of the five phenotypic classes PI*MS, PI*MZ, PI*SS, PI*SZ, and PI*ZZ: a comprehensive review | Therapeutic Advances in Respiratory Disease | 2012 | 161 |
| 22 | Role of CYP2E1 in the Epoxidation of Acrylamide to Glycidamide and Formation of DNA and Hemoglobin Adducts | Toxicological Sciences | 2005 | 160 |
| 23 | In silico toxicology protocols | Regulatory Toxicology and Pharmacology | 2018 | 159 |
| 24 | Comparative cytogenetic analysis of bone marrow damage induced in male B6C3F1 mice by multiple exposures to gaseous 1,3-butadiene | Environmental Mutagenesis | 1987 | 157 |
| 25 | Migration of Intradermally Injected Quantum Dots to Sentinel Organs in Mice | Toxicological Sciences | 2007 | 156 |
| 26 | A high-throughput method for assessing chemical toxicity using a Caenorhabditis elegans reproduction assay | Toxicology and Applied Pharmacology | 2010 | 148 |
| 27 | Testicular toxicity of boric acid (BA): Relationship of dose to lesion development and recovery in the F344 rat | Reproductive Toxicology | 1993 | 139 |
| 28 | The in vivo Pig-a assay: A report of the International Workshop On Genotoxicity Testing (IWGT) Workgroup | Mutation Research - Genetic Toxicology and Environmental Mutagenesis | 2015 | 139 |
| 29 | Results and evaluations of 48 continuous breeding reproduction studies conducted in mice | Fundamental and Applied Toxicology | 1989 | 138 |
| 30 | The US Federal Tox21 Program: A strategic and operational plan for continued leadership | ALTEX: Alternatives To Animal Experimentation | 2018 | 134 |
| 31 | Endocrine Disruptors and the Breast: Early Life Effects and Later Life Disease | Journal of Mammary Gland Biology and Neoplasia | 2013 | 129 |
| 32 | Recommendations from the INHAND Apoptosis/Necrosis Working Group | Toxicologic Pathology | 2016 | 129 |
| 33 | National Toxicology Program Nomenclature for Hepatoproliferative Lesions of Rats | Toxicologic Pathology | 1986 | 126 |
| 34 | Evaluation of rodent sperm, vaginal cytology, and reproductive organ weight data from National Toxicology Program 13-week studies | Fundamental and Applied Toxicology | 1988 | 123 |
| 35 | BMDExpress 2: enhanced transcriptomic dose-response analysis workflow | Bioinformatics | 2019 | 123 |
| 36 | Estimation of Variance for AUC in Animal Studies | Journal of Pharmaceutical Sciences | 1993 | 122 |
| 37 | Growth, Body Weight, Survival, and Tumor Trends in F344/N Rats during an Eleven-Year Period | Toxicologic Pathology | 1990 | 120 |
| 38 | Diagnostic Criteria for Degenerative, Inflammatory, Proliferative Nonneoplastic and Neoplastic Liver Lesions in Medaka (Oryzias latipes): Consensus of a National Toxicology Program Pathology Working Group | Toxicologic Pathology | 1997 | 120 |
| 39 | Cancer in experimental animals exposed to arsenic and arsenic compounds | Critical Reviews in Toxicology | 2010 | 120 |
| 40 | An overview of prechronic and chronic toxicity/carcinogenicity experimental study designs and criteria used by the National Toxicology Program. | Environmental Health Perspectives | 1990 | 119 |
| 41 | Differential Follicle Counts as a Screen for Chemically Induced Ovarian Toxicity in Mice: Results from Continuous Breeding Bioassays | Fundamental and Applied Toxicology | 1997 | 119 |
| 42 | Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System | Journal of Toxicologic Pathology | 2014 | 116 |
| 43 | A Short-term In Vivo Screen Using Fetal Testosterone Production, a Key Event in the Phthalate Adverse Outcome Pathway, to Predict Disruption of Sexual Differentiation | Toxicological Sciences | 2014 | 115 |
| 44 | Perinatal thymocyte antigen expression and postnatal immune development altered by gestational exposure to tetrachlorodibenzo-p-dioxin (TCDD) | Teratology | 1991 | 114 |
| 45 | Caenorhabditis elegans as a Model in Developmental Toxicology | Methods in Molecular Biology | 2012 | 114 |
| 46 | Chemicals showing no evidence of carcinogenicity in long-term, two-species rodent studies: The need for short-term test data | Environmental Mutagenesis | 1984 | 110 |
| 47 | Nonproliferative and Proliferative Lesions ofthe Gastrointestinal Tract, Pancreas andSalivary Glands of the Rat and Mouse | Journal of Toxicologic Pathology | 2016 | 109 |
| 48 | TCDD alters medial epithelial cell differentiation during palatogenesis | Toxicology and Applied Pharmacology | 1989 | 108 |
| 49 | The carcinogenesis bioassay in perspective: application in identifying human cancer hazards. | Environmental Health Perspectives | 1995 | 104 |
| 50 | Medium- and high-throughput screening of neurotoxicants using C. elegans | Neurotoxicology and Teratology | 2010 | 102 |
