| # | Title | Journal | Year | Citations |
|---|
| 1 | The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine | Nature | 1980 | 11,108 |
| 2 | Derivation and validation of the Systemic Lupus International Collaborating Clinics classification criteria for systemic lupus erythematosus | Arthritis and Rheumatism | 2012 | 3,838 |
| 3 | Postoperative Concurrent Radiotherapy and Chemotherapy for High-Risk Squamous-Cell Carcinoma of the Head and Neck | New England Journal of Medicine | 2004 | 2,756 |
| 4 | Clopidogrel and Aspirin versus Aspirin Alone for the Prevention of Atherothrombotic Events | New England Journal of Medicine | 2006 | 2,582 |
| 5 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
| 6 | The mechanism of eukaryotic translation initiation and principles of its regulation | Nature Reviews Molecular Cell Biology | 2010 | 2,160 |
| 7 | Ivabradine and outcomes in chronic heart failure (SHIFT): a randomised placebo-controlled study | Lancet, The | 2010 | 2,119 |
| 8 | The American College of Rheumatology 1990 criteria for the classification of giant cell arteritis | Arthritis and Rheumatism | 1990 | 2,068 |
| 9 | National Institute on Aging–Alzheimer’s Association guidelines for the neuropathologic assessment of Alzheimer’s disease: a practical approach | Acta Neuropathologica | 2012 | 2,002 |
| 10 | National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease | Alzheimer's and Dementia | 2012 | 1,968 |
| 11 | American College of Gastroenterology Guideline: Management of Acute Pancreatitis | American Journal of Gastroenterology | 2013 | 1,686 |
| 12 | The American College of Rheumatology 1990 criteria for the classification of wegener's granulomatosis | Arthritis and Rheumatism | 1990 | 1,620 |
| 13 | 5′ UTR m6A Promotes Cap-Independent Translation | Cell | 2015 | 1,414 |
| 14 | The classification of glomerulonephritis in systemic lupus erythematosus revisited | Kidney International | 2004 | 1,272 |
| 15 | Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial | Lancet, The | 2010 | 1,182 |
| 16 | Epidemiology of Adult DSM-5 Major Depressive Disorder and Its Specifiers in the United States | JAMA Psychiatry | 2018 | 1,107 |
| 17 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 18 | Mycophenolate Mofetil or Intravenous Cyclophosphamide for Lupus Nephritis | New England Journal of Medicine | 2005 | 991 |
| 19 | VESICLES ASSOCIATED WITH CALCIFICATION IN THE MATRIX OF EPIPHYSEAL CARTILAGE | Journal of Cell Biology | 1969 | 967 |
| 20 | The American college of rheumatology 1990 criteria for the classification of polyarteritis nodosa | Arthritis and Rheumatism | 1990 | 937 |
| 21 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 22 | Mortality in systemic lupus erythematosus | Arthritis and Rheumatism | 2006 | 924 |
| 23 | AN IMPROVED STAINING METHOD FOR ELECTRON MICROSCOPY | Journal of Cell Biology | 1964 | 792 |
| 24 | Clinical practice guideline: Adult sinusitis | Otolaryngology - Head and Neck Surgery | 2007 | 788 |
| 25 | Clinical Practice Guideline: Tonsillectomy in Children | Otolaryngology - Head and Neck Surgery | 2011 | 788 |
| 26 | Clinical Practice Guideline | Otolaryngology - Head and Neck Surgery | 2012 | 787 |
| 27 | Heart rate as a risk factor in chronic heart failure (SHIFT): the association between heart rate and outcomes in a randomised placebo-controlled trial | Lancet, The | 2010 | 769 |
| 28 | Patients With Prior Myocardial Infarction, Stroke, or Symptomatic Peripheral Arterial Disease in the CHARISMA Trial | Journal of the American College of Cardiology | 2007 | 752 |
| 29 | Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis | Nature Medicine | 2011 | 750 |
| 30 | Storage of Spatial Information by the Maintenance Mechanism of LTP | Science | 2006 | 747 |
| 31 | Chronux: A platform for analyzing neural signals | Journal of Neuroscience Methods | 2010 | 747 |
| 32 | Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer | Cancer Discovery | 2018 | 676 |
| 33 | Dietary carbohydrate restriction as the first approach in diabetes management: Critical review and evidence base | Nutrition | 2015 | 666 |
| 34 | Clinical Practice Guideline: Otitis Media with Effusion (Update) | Otolaryngology - Head and Neck Surgery | 2016 | 660 |
| 35 | Hydroxycarbamide in very young children with sickle-cell anaemia: a multicentre, randomised, controlled trial (BABY HUG) | Lancet, The | 2011 | 647 |
| 36 | Pioglitazone for Diabetes Prevention in Impaired Glucose Tolerance | New England Journal of Medicine | 2011 | 646 |
| 37 | Clinical Practice Guideline (Update): Adult Sinusitis | Otolaryngology - Head and Neck Surgery | 2015 | 640 |
| 38 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 39 | Characteristics and Outcomes of US Children and Adolescents With Multisystem Inflammatory Syndrome in Children (MIS-C) Compared With Severe Acute COVID-19 | JAMA - Journal of the American Medical Association | 2021 | 617 |
| 40 | LACTATE CLEARANCE AND SURVIVAL FOLLOWING INJURY | Journal of Trauma | 1993 | 600 |
| 41 | Intestinal lipid absorption | American Journal of Physiology - Endocrinology and Metabolism | 2009 | 595 |
| 42 | Best practice policies for male infertility | Fertility and Sterility | 2002 | 573 |
| 43 | Stem Cells in the Treatment of Refractory Chronic Migraines | Case Reports in Neurology | 2017 | 556 |
| 44 | The American College of Rheumatology 1990 criteria for the classification of vasculitis: Introduction | Arthritis and Rheumatism | 1990 | 553 |
| 45 | Local radiotherapy and granulocyte-macrophage colony-stimulating factor to generate abscopal responses in patients with metastatic solid tumours: a proof-of-principle trial | Lancet Oncology, The | 2015 | 546 |
| 46 | Mycophenolate versus Azathioprine as Maintenance Therapy for Lupus Nephritis | New England Journal of Medicine | 2011 | 544 |
| 47 | Comparison of Early Intervention Services vs Treatment as Usual for Early-Phase Psychosis | JAMA Psychiatry | 2018 | 516 |
| 48 | Integrative functional genomic analysis of human brain development and neuropsychiatric risks | Science | 2018 | 516 |
| 49 | A phase II, randomized, double‐blind, placebo‐controlled, dose‐ranging study of belimumab in patients with active systemic lupus erythematosus | Arthritis and Rheumatism | 2009 | 515 |
| 50 | COMPARISON OF DISSOCIATION CONSTANTS AND OF RELATIVE EFFICACIES OF SELECTED AGONISTS ACTING ON PARASYMPATHETIC RECEPTORS | Annals of the New York Academy of Sciences | 1967 | 513 |
