| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 3 | Whole genome sequencing of meticillin-resistant Staphylococcus aureus | Lancet, The | 2001 | 1,835 |
| 4 | Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update | Hepatology International | 2017 | 1,537 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 6 | LC3 and Autophagy | Methods in Molecular Biology | 2008 | 1,311 |
| 7 | Genome and virulence determinants of high virulence community-acquired MRSA | Lancet, The | 2002 | 1,223 |
| 8 | LC3 conjugation system in mammalian autophagy | International Journal of Biochemistry and Cell Biology | 2004 | 1,223 |
| 9 | Dissemination in Japanese hospitals of strains of Staphylococcus aureus heterogeneously resistant to vancomycin | Lancet, The | 1997 | 1,196 |
| 10 | Role of the Basal Ganglia in the Control of Purposive Saccadic Eye Movements | Physiological Reviews | 2000 | 1,061 |
| 11 | The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification | Kidney International | 2009 | 1,028 |
| 12 | The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility | Kidney International | 2009 | 892 |
| 13 | Combination of Multiplex PCRs for Staphylococcal Cassette Chromosome mec Type Assignment: Rapid Identification System for mec , ccr , and MajorDifferences in Junkyard Regions | Antimicrobial Agents and Chemotherapy | 2007 | 886 |
| 14 | Structural Comparison of Three Types of Staphylococcal Cassette Chromosome mec Integrated in the Chromosome in Methicillin-Resistant Staphylococcus aureus | Antimicrobial Agents and Chemotherapy | 2001 | 860 |
| 15 | A New Class of Genetic Element, Staphylococcus Cassette Chromosome mec , Encodes Methicillin Resistance in Staphylococcus aureus | Antimicrobial Agents and Chemotherapy | 2000 | 836 |
| 16 | Dissemination of New Methicillin-Resistant Staphylococcus aureus Clones in the Community | Journal of Clinical Microbiology | 2002 | 810 |
| 17 | Role for Rab7 in maturation of late autophagic vacuoles | Journal of Cell Science | 2004 | 781 |
| 18 | Range of antinuclear antibodies in “healthy” individuals | Arthritis and Rheumatism | 1997 | 758 |
| 19 | Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial | Lancet, The | 2017 | 753 |
| 20 | Specific acceptance of cardiac allograft after treatment with antibodies to ICAM-1 and LFA-1 | Science | 1992 | 734 |
| 21 | Deficiencies in Complex I subunits of the respiratory chain in Parkinson's disease | Biochemical and Biophysical Research Communications | 1989 | 720 |
| 22 | Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019 | JAMA Oncology | 2022 | 719 |
| 23 | Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts | Journal of Experimental Medicine | 2010 | 715 |
| 24 | Parallel neural networks for learning sequential procedures | Trends in Neurosciences | 1999 | 702 |
| 25 | Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase | Journal of Clinical Investigation | 2007 | 698 |
| 26 | Generation of transgenic non-human primates with germline transmission | Nature | 2009 | 675 |
| 27 | Classification of Staphylococcal Cassette Chromosome mec (SCC mec ): Guidelines for Reporting Novel SCC mec Elements | Antimicrobial Agents and Chemotherapy | 2009 | 669 |
| 28 | The emergence and evolution of methicillin-resistant Staphylococcus aureus | Trends in Microbiology | 2001 | 655 |
| 29 | Vancomycin-resistant Staphylococcus aureus : a new model of antibiotic resistance | Lancet Infectious Diseases, The | 2001 | 641 |
| 30 | SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations | Nature Genetics | 2008 | 641 |
| 31 | The IASLC Lung Cancer Staging Project: Proposals for the Revisions of the T Descriptors in the Forthcoming Eighth Edition of the TNM Classification for Lung Cancer | Journal of Thoracic Oncology | 2015 | 628 |
| 32 | Mitochondrial Electron Transport Complex I Is a Potential Source of Oxygen Free Radicals in the Failing Myocardium | Circulation Research | 1999 | 615 |
| 33 | Novel Type V Staphylococcal Cassette Chromosome mec Driven by a Novel Cassette Chromosome Recombinase, ccrC | Antimicrobial Agents and Chemotherapy | 2004 | 599 |
| 34 | IL-33 is a crucial amplifier of innate rather than acquired immunity | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 594 |
| 35 | Improved Efficacy of Neoadjuvant Compared to Adjuvant Immunotherapy to Eradicate Metastatic Disease | Cancer Discovery | 2016 | 592 |
| 36 | The Pathophysiology of IgA Nephropathy | Journal of the American Society of Nephrology: JASN | 2011 | 584 |
| 37 | Expectation of reward modulates cognitive signals in the basal ganglia | Nature Neuroscience | 1998 | 567 |
| 38 | Scientific and Standardization Committee communication: Clinical guidance on the diagnosis, prevention, and treatment of venous thromboembolism in hospitalized patients with COVID‐19 | Journal of Thrombosis and Haemostasis | 2020 | 547 |
| 39 | Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017 | Journal of Atherosclerosis and Thrombosis | 2018 | 541 |
| 40 | Sarcopenia, intramuscular fat deposition, and visceral adiposity independently predict the outcomes of hepatocellular carcinoma | Journal of Hepatology | 2015 | 538 |
| 41 | Novel Type of Staphylococcal Cassette Chromosome mec Identified in Community-Acquired Methicillin-Resistant Staphylococcus aureus Strains | Antimicrobial Agents and Chemotherapy | 2002 | 526 |
| 42 | Genome Sequence of Staphylococcus aureus Strain Newman and Comparative Analysis of Staphylococcal Genomes: Polymorphism and Evolution of Two Major Pathogenicity Islands | Journal of Bacteriology | 2008 | 511 |
| 43 | Guidelines for Management of Idiopathic Normal Pressure Hydrocephalus: Second Edition | Neurologia Medico-Chirurgica | 2012 | 506 |
| 44 | Discovery of new risk loci for IgA nephropathy implicates genes involved in immunity against intestinal pathogens | Nature Genetics | 2014 | 505 |
| 45 | Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells | Nature Immunology | 2017 | 504 |
| 46 | Mutations in ATP2C1, encoding a calcium pump, cause Hailey-Hailey disease | Nature Genetics | 2000 | 498 |
| 47 | Novel scoring system and algorithm for classifying chronic rhinosinusitis: the JESREC Study | Allergy: European Journal of Allergy and Clinical Immunology | 2015 | 495 |
| 48 | Two-component system VraSR positively modulates the regulation of cell-wall biosynthesis pathway in Staphylococcus aureus | Molecular Microbiology | 2004 | 494 |
| 49 | Association of structural polymorphisms in the human period3 gene with delayed sleep phase syndrome | EMBO Reports | 2001 | 485 |
| 50 | COPD in Japan: the Nippon COPD Epidemiology study | Respirology | 2004 | 482 |
