Mutations in PCSK9 cause autosomal dominant hypercholesterolemia | Nature Genetics | 2003 | 2K |
Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells | Nature | 2003 | 1.2K |
The secretory proprotein convertase neural apoptosis-regulated convertase 1 (NARC-1): liver regeneration and neuronal differentiation | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 857 |
In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein | Nature Medicine | 2003 | 256 |
Pitx3 is required for motor activity and for survival of a subset of midbrain dopaminergic neurons | Development (Cambridge) | 2003 | 239 |
c-Src induces phosphorylation and translocation of p47phox: role in superoxide generation by angiotensin II in human vascular smooth muscle cells | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 237 |
Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation | Nature Cell Biology | 2003 | 226 |
Endothelin antagonism on aldosterone-induced oxidative stress and vascular remodeling | Hypertension | 2003 | 205 |
Effect of peroxisome proliferator-activated receptor-alpha and -gamma activators on vascular remodeling in endothelin-dependent hypertension | Arteriosclerosis, Thrombosis, and Vascular Biology | 2003 | 175 |
Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension | Clinical and Experimental Pharmacology and Physiology | 2003 | 169 |
A serine protease inhibitor prevents endoplasmic reticulum stress-induced cleavage but not transport of the membrane-bound transcription factor ATF6 | Journal of Biological Chemistry | 2003 | 161 |
Human and mouse TPIT gene mutations cause early onset pituitary ACTH deficiency | Genes and Development | 2003 | 157 |
Tpit determines alternate fates during pituitary cell differentiation | Genes and Development | 2003 | 156 |
Role of magnesium in the pathogenesis of hypertension | Molecular Aspects of Medicine | 2003 | 148 |
Transcriptional activation of BMP-4 and regulation of mammalian organogenesis by GATA-4 and -6 | Developmental Biology | 2003 | 144 |
Vascular inflammation: a role in vascular disease in hypertension? | Current Opinion in Nephrology and Hypertension | 2003 | 139 |
Peroxisome proliferator-activated receptor-alpha and receptor-gamma activators prevent cardiac fibrosis in mineralocorticoid-dependent hypertension | Hypertension | 2003 | 132 |
Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency | FASEB Journal | 2003 | 130 |
Reactive oxygen species in vascular biology: role in arterial hypertension | Expert Review of Cardiovascular Therapy | 2003 | 117 |
Crimean-Congo hemorrhagic fever virus glycoprotein proteolytic processing by subtilase SKI-1 | Journal of Virology | 2003 | 116 |
Role of endothelin in human hypertension | Canadian Journal of Physiology and Pharmacology | 2003 | 115 |
Peroxisome proliferator-activated receptors: vascular and cardiac effects in hypertension | Hypertension | 2003 | 114 |
Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells | Journal of Biological Chemistry | 2003 | 110 |
The role of angiotensin II in regulating vascular structural and functional changes in hypertension | Current Hypertension Reports | 2003 | 109 |
Registration and fusion of retinal images--an evaluation study | IEEE Transactions on Medical Imaging | 2003 | 101 |