| Signal transduction mechanisms mediating the physiological and pathophysiological actions of angiotensin II in vascular smooth muscle cells | Pharmacological Reviews | 2000 | 596 |
| Correction of arterial structure and endothelial dysfunction in human essential hypertension by the angiotensin receptor antagonist losartan | Circulation | 2000 | 531 |
| Structure and mechanical properties of resistance arteries in hypertension: role of adhesion molecules and extracellular matrix determinants | Hypertension | 2000 | 359 |
| SCL and LMO1 alter thymocyte differentiation: inhibition of E2A-HEB function and pre-T alpha chain expression | Nature Immunology | 2000 | 178 |
| Estrogen deficiency, obesity, and skeletal abnormalities in follicle-stimulating hormone receptor knockout (FORKO) female mice | Endocrinology | 2000 | 174 |
| Docosahexaenoic acid, a peroxisome proliferator-activated receptor-alpha ligand, induces apoptosis in vascular smooth muscle cells by stimulation of p38 mitogen-activated protein kinase | Hypertension | 2000 | 153 |
| Oxidative stress and vascular damage in hypertension | Current Hypertension Reports | 2000 | 153 |
| Qualitative and quantitative decline in spermatogenesis of the follicle-stimulating hormone receptor knockout (FORKO) mouse | Biology of Reproduction | 2000 | 145 |
| Coordinated expression of beta-amyloid precursor protein and the putative beta-secretase BACE and alpha-secretase ADAM10 in mouse and human brain | Journal of Neurochemistry | 2000 | 143 |
| Synthesis and in vitro opioid activity profiles of DALDA analogues | European Journal of Medicinal Chemistry | 2000 | 138 |
| Physiological and pathophysiological role of magnesium in the cardiovascular system: implications in hypertension | Journal of Hypertension | 2000 | 118 |
| Neurotrophin-3 sorts to the constitutive secretory pathway of hippocampal neurons and is diverted to the regulated secretory pathway by coexpression with brain-derived neurotrophic factor | Journal of Neuroscience | 2000 | 104 |
| Cholesterol efflux regulatory protein, Tangier disease and familial high-density lipoprotein deficiency | Current Opinion in Lipidology | 2000 | 99 |
| Endoproteolytic processing of integrin pro-α subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7 | Biochemical Journal | 2000 | 86 |
| Activation of extracellular-regulated kinase pathways in ovarian granulosa cells by the novel growth factor type 1 follicle-stimulating hormone receptor. Role in hormone signaling and cell proliferation | Journal of Biological Chemistry | 2000 | 83 |
| Two distinct Notch1 mutant alleles are involved in the induction of T-cell leukemia in c-myc transgenic mice | Molecular and Cellular Biology | 2000 | 77 |
| Biosynthesis and enzymatic characterization of human SKI-1/S1P and the processing of its inhibitory prosegment | Journal of Biological Chemistry | 2000 | 72 |
| Vasopeptidase inhibition has potent effects on blood pressure and resistance arteries in stroke-prone spontaneously hypertensive rats | Hypertension | 2000 | 61 |
| Reduction of resistance artery stiffness by treatment with the AT(1)-receptor antagonist losartan in essential hypertension | JRAAS - Journal of the Renin-Angiotensin-Aldosterone System | 2000 | 55 |
| AP-1 complex is effector of Hox-induced cellular proliferation and transformation | Oncogene | 2000 | 48 |
| Regional and cellular localization of the neuroendocrine prohormone convertases PC1 and PC2 in the rat central nervous system | Journal of Comparative Neurology | 2000 | 47 |
| Novel ligands lacking a positive charge for the delta- and mu-opioid receptors | Journal of Medicinal Chemistry | 2000 | 47 |
| Contribution of circulating renin to local synthesis of angiotensin peptides in the heart | Physiological Genomics | 2000 | 46 |
| Effect of micronized fenofibrate on plasma lipoprotein levels and hemostatic parameters of hypertriglyceridemic patients with low levels of high-density lipoprotein cholesterol in the fed and fasted state | Journal of Cardiovascular Pharmacology | 2000 | 44 |
| Effect of deprival of LH on Leydig cell proliferation: involvement of PCNA, cyclin D3 and IGF-1 | Molecular and Cellular Endocrinology | 2000 | 43 |
