| An atlas of genetic influences on human blood metabolites | Nature Genetics | 2014 | 695 |
| Frailty assessment in the cardiovascular care of older adults | Journal of the American College of Cardiology | 2014 | 608 |
| Expert consensus for multimodality imaging evaluation of adult patients during and after cancer therapy: a report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging | European Heart Journal Cardiovascular Imaging | 2014 | 526 |
| Use of statins and the risk of death in patients with prostate cancer | Journal of Clinical Oncology | 2014 | 440 |
| Compression stockings to prevent post-thrombotic syndrome: a randomised placebo-controlled trial | Lancet, The | 2014 | 322 |
| Germline and somatic SMARCA4 mutations characterize small cell carcinoma of the ovary, hypercalcemic type | Nature Genetics | 2014 | 305 |
| Warfarin use and the risk for stroke and bleeding in patients with atrial fibrillation undergoing dialysis | Circulation | 2014 | 238 |
| Methotrexate in combination with infliximab is no more effective than infliximab alone in patients with Crohn's disease | Gastroenterology | 2014 | 237 |
| Vemurafenib in patients with BRAF(V600) mutated metastatic melanoma: an open-label, multicentre, safety study | Lancet Oncology, The | 2014 | 206 |
| The 2014 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension | Canadian Journal of Cardiology | 2014 | 198 |
| The IRP/IRE system in vivo: insights from mouse models | Frontiers in Pharmacology | 2014 | 184 |
| Global experience with an inner branched arch endograft | Journal of Thoracic and Cardiovascular Surgery | 2014 | 177 |
| Point-of-care ultrasonography for the diagnosis of acute cardiogenic pulmonary edema in patients presenting with acute dyspnea: a systematic review and meta-analysis | Academic Emergency Medicine | 2014 | 176 |
| Noninvasive diagnosis of actionable mutations by deep sequencing of circulating free DNA in lung cancer from never-smokers: a proof-of-concept study from BioCAST/IFCT-1002 | Clinical Cancer Research | 2014 | 171 |
| Antepartum dalteparin versus no antepartum dalteparin for the prevention of pregnancy complications in pregnant women with thrombophilia (TIPPS): a multinational open-label randomised trial | Lancet, The | 2014 | 168 |
| An update on a systematic review of the use of geriatric assessment for older adults in oncology | Annals of Oncology | 2014 | 163 |
| Pituitary blastoma: a pathognomonic feature of germ-line DICER1 mutations | Acta Neuropathologica | 2014 | 160 |
| Oxytocin in pregnancy and the postpartum: relations to labor and its management | Frontiers in Public Health | 2014 | 153 |
| Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells | PLoS Pathogens | 2014 | 153 |
| Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis | American Journal of Human Genetics | 2014 | 151 |
| Prognostic significance of FOXP3+ tumor-infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration | Breast Cancer Research | 2014 | 137 |
| The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation | Nature | 2014 | 129 |
| Futility, benefit, and transcatheter aortic valve replacement | JACC: Cardiovascular Interventions | 2014 | 126 |
| The validity of circulating microRNAs in oncology: five years of challenges and contradictions | Molecular Oncology | 2014 | 125 |
| Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis | Gut | 2014 | 124 |
