| # | Title | Journal | Year | Citations |
|---|
| 1 | MDS clinical diagnostic criteria for Parkinson's disease | Movement Disorders | 2015 | 4,389 |
| 2 | The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity | Arthritis Care and Research | 2010 | 2,964 |
| 3 | DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES | Journal of Experimental Medicine | 1965 | 2,282 |
| 4 | The development and initial validation of the systemic lupus international collaborating clinics/American college of rheumatology damage index for systemic lupus erythematosus | Arthritis and Rheumatism | 1996 | 2,042 |
| 5 | SPECIFIC CARCINOEMBRYONIC ANTIGENS OF THE HUMAN DIGESTIVE SYSTEM | Journal of Experimental Medicine | 1965 | 1,819 |
| 6 | Risks of cancer in BRCA1-mutation carriers | Lancet, The | 1994 | 1,764 |
| 7 | Axonal elongation into peripheral nervous system "bridges" after central nervous system injury in adult rats | Science | 1981 | 1,617 |
| 8 | Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency | Nature Genetics | 1999 | 1,609 |
| 9 | The Academic Motivation Scale: A Measure of Intrinsic, Extrinsic, and Amotivation in Education | Educational and Psychological Measurement | 1992 | 1,593 |
| 10 | REVEL: An Ensemble Method for Predicting the Pathogenicity of Rare Missense Variants | American Journal of Human Genetics | 2016 | 1,555 |
| 11 | Specialized Membrane Domains for Water Transport in Glial Cells: High-Resolution Immunogold Cytochemistry of Aquaporin-4 in Rat Brain | Journal of Neuroscience | 1997 | 1,314 |
| 12 | Reduced Expression of Endothelial Nitric Oxide Synthase in the Lungs of Patients with Pulmonary Hypertension | New England Journal of Medicine | 1995 | 1,256 |
| 13 | ESPEN guideline: Clinical nutrition in surgery | Clinical Nutrition | 2017 | 1,240 |
| 14 | The Use of β-Agonists and the Risk of Death and near Death from Asthma | New England Journal of Medicine | 1992 | 1,228 |
| 15 | Guidelines for Perioperative Care in Elective Colorectal Surgery: Enhanced Recovery After Surgery (ERAS®) Society Recommendations: 2018 | World Journal of Surgery | 2019 | 1,166 |
| 16 | Traditional Framingham risk factors fail to fully account for accelerated atherosclerosis in systemic lupus erythematosus | Arthritis and Rheumatism | 2001 | 1,051 |
| 17 | MDS research criteria for prodromal Parkinson's disease | Movement Disorders | 2015 | 1,033 |
| 18 | Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice | Science | 2003 | 994 |
| 19 | Incidence of and Risk Factors for Falls and Injurious Falls among the Community-dwelling Elderly | American Journal of Epidemiology | 1993 | 975 |
| 20 | Mortality in systemic lupus erythematosus | Arthritis and Rheumatism | 2006 | 924 |
| 21 | Axons from CNS neurones regenerate into PNS grafts | Nature | 1980 | 904 |
| 22 | Dysferlin, a novel skeletal muscle gene, is mutated in Miyoshi myopathy and limb girdle muscular dystrophy | Nature Genetics | 1998 | 857 |
| 23 | 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult | Canadian Journal of Cardiology | 2016 | 775 |
| 24 | Flow patterns and spatial distribution of atherosclerotic lesions in human coronary arteries. | Circulation Research | 1990 | 758 |
| 25 | Short GCG expansions in the PABP2 gene cause oculopharyngeal muscular dystrophy | Nature Genetics | 1998 | 751 |
| 26 | Insulin expression in human thymus is modulated by INS VNTR alleles at the IDDM2 locus | Nature Genetics | 1997 | 745 |
| 27 | Quantifying the risk of neurodegenerative disease in idiopathic REM sleep behavior disorder | Neurology | 2009 | 710 |
| 28 | Characteristics of bone ingrowth and interface mechanics of a new porous tantalum biomaterial | Journal of Bone and Joint Surgery: British Volume | 1999 | 667 |
| 29 | Risk and predictors of dementia and parkinsonism in idiopathic REM sleep behaviour disorder: a multicentre study | Brain | 2019 | 636 |
| 30 | Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy | Movement Disorders | 2017 | 608 |
| 31 | The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology damage index in patients with Systemic Lupus Erythematosus | Arthritis and Rheumatism | 1997 | 586 |
| 32 | Summary and agreement statement of the first International Conference on Concussion in Sport, Vienna 2001 | British Journal of Sports Medicine | 2002 | 585 |
| 33 | Basal Ganglia Functional Connectivity Based on a Meta-Analysis of 126 Positron Emission Tomography and Functional Magnetic Resonance Imaging Publications | Cerebral Cortex | 2006 | 581 |
| 34 | SpekCalc: a program to calculate photon spectra from tungsten anode x-ray tubes | Physics in Medicine and Biology | 2009 | 556 |
| 35 | Fungal infections in cancer patients: An international autopsy survey | European Journal of Clinical Microbiology and Infectious Diseases | 1992 | 542 |
| 36 | Astrocytes Are Endogenous Regulators of Basal Transmission at Central Synapses | Cell | 2011 | 536 |
| 37 | The Quebec Back Pain Disability Scale | Spine | 1995 | 527 |
| 38 | Arabinosyl Cytosine: A Useful Agent in the Treatment of Acute Leukemia in Adults | Blood | 1968 | 521 |
| 39 | Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas | Nature Genetics | 1994 | 514 |
| 40 | Adult Stillʼs Disease | Medicine (United States) | 1991 | 502 |
| 41 | A multicenter, randomized, double-blind, placebo-controlled trial of adjuvant methotrexate treatment for giant cell arteritis | Arthritis and Rheumatism | 2002 | 480 |
| 42 | Enhanced Recovery After Surgery (ERAS) for gastrointestinal surgery, part 2: consensus statement for anaesthesia practice | Acta Anaesthesiologica Scandinavica | 2016 | 479 |
| 43 | Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2018 | 474 |
| 44 | Proteoglycan-induced arthritis in balb/c mice | Arthritis and Rheumatism | 1987 | 463 |
| 45 | On the Assessment of Intrinsic, Extrinsic, and Amotivation in Education: Evidence on the Concurrent and Construct Validity of the Academic Motivation Scale | Educational and Psychological Measurement | 1993 | 463 |
| 46 | New Clinical Subtypes of Parkinson Disease and Their Longitudinal Progression | JAMA Neurology | 2015 | 456 |
| 47 | Depressant action of TRH, LH-RH and somatostatin on activity of central neurones | Nature | 1975 | 452 |
| 48 | Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis | Human Molecular Genetics | 1994 | 452 |
| 49 | Peripheral injury enhances central regeneration of primary sensory neurones | Nature | 1984 | 451 |
| 50 | Common variants in the NLRP3 region contribute to Crohn's disease susceptibility | Nature Genetics | 2009 | 448 |
