| Standard-dose versus high-dose conformal radiotherapy with concurrent and consolidation carboplatin plus paclitaxel with or without cetuximab for patients with stage IIIA or IIIB non-small-cell lung cancer (RTOG 0617): a randomised, two-by-two factorial phase 3 study | Lancet Oncology, The | 2015 | 1.2K |
| Ledipasvir and Sofosbuvir for HCV in Patients Coinfected with HIV-1 | New England Journal of Medicine | 2015 | 382 |
| Association between hospitalization for pneumonia and subsequent risk of cardiovascular disease | JAMA - Journal of the American Medical Association | 2015 | 308 |
| PDK1-Dependent Metabolic Reprogramming Dictates Metastatic Potential in Breast Cancer | Cell Metabolism | 2015 | 308 |
| The increasing burden and complexity of multimorbidity | BMC Public Health | 2015 | 276 |
| Indications for Autologous and Allogeneic Hematopoietic Cell Transplantation: Guidelines from the American Society for Blood and Marrow Transplantation | Biology of Blood and Marrow Transplantation | 2015 | 253 |
| Location of colon cancer (right-sided versus left-sided) as a prognostic factor and a predictor of benefit from cetuximab in NCIC CO.17 | European Journal of Cancer | 2015 | 233 |
| Increasing incidence of chronic graft-versus-host disease in allogeneic transplantation: a report from the Center for International Blood and Marrow Transplant Research | Biology of Blood and Marrow Transplantation | 2015 | 214 |
| Striatal blood-brain barrier permeability in Parkinson's disease | Journal of Cerebral Blood Flow and Metabolism | 2015 | 189 |
| Can Quantitative CT Texture Analysis be Used to Differentiate Fat-poor Renal Angiomyolipoma from Renal Cell Carcinoma on Unenhanced CT Images? | Radiology | 2015 | 187 |
| Efficacy of sofosbuvir plus ribavirin with or without peginterferon-alfa in patients with hepatitis C virus genotype 3 infection and treatment-experienced patients with cirrhosis and hepatitis C virus genotype 2 infection | Gastroenterology | 2015 | 178 |
| Pathophysiology and Immune Dysfunction in Endometriosis | BioMed Research International | 2015 | 178 |
| Canadian Stroke Best Practice Recommendations: Hyperacute Stroke Care Guidelines, Update 2015 | International Journal of Stroke | 2015 | 159 |
| A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by breast-conserving surgery alone | Breast Cancer Research and Treatment | 2015 | 152 |
| Comparison of standard and accelerated initiation of renal replacement therapy in acute kidney injury | Kidney International | 2015 | 139 |
| Atrial premature beats predict atrial fibrillation in cryptogenic stroke: results from the EMBRACE trial | Stroke | 2015 | 123 |
| The influence of time from injury to surgery on motor recovery and length of hospital stay in acute traumatic spinal cord injury: an observational Canadian cohort study | Journal of Neurotrauma | 2015 | 118 |
| Sonography of the Optic Nerve Sheath Diameter for Detection of Raised Intracranial Pressure Compared to Computed Tomography: A Systematic Review and Meta-analysis | Journal of Ultrasound in Medicine | 2015 | 112 |
| Impact of crisis resource management simulation-based training for interprofessional and interdisciplinary teams: A systematic review | Journal of Interprofessional Care | 2015 | 111 |
| A contemporary survival analysis of individuals with cystic fibrosis: a cohort study | European Respiratory Journal | 2015 | 111 |
| Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of cisplatin-based highly emetogenic chemotherapy in patients with cancer: two randomised, active-controlled, double-blind, phase 3 trials | Lancet Oncology, The | 2015 | 110 |
| Quantitative CT texture and shape analysis: can it differentiate benign and malignant mediastinal lymph nodes in patients with primary lung cancer? | European Radiology | 2015 | 108 |
| Perioperative use of pregabalin for acute pain-a systematic review and meta-analysis | Pain | 2015 | 108 |
| Safety and efficacy of rolapitant for prevention of chemotherapy-induced nausea and vomiting after administration of moderately emetogenic chemotherapy or anthracycline and cyclophosphamide regimens in patients with cancer: a randomised, active-controlled, double-blind, phase 3 trial | Lancet Oncology, The | 2015 | 106 |
| The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis | Critical Care Medicine | 2015 | 104 |
