| # | Title | Journal | Year | Citations |
|---|
| 1 | PRISMA Extension for Scoping Reviews (PRISMA-ScR): Checklist and Explanation | Annals of Internal Medicine | 2018 | 15,209 |
| 2 | RoB 2: a revised tool for assessing risk of bias in randomised trials | BMJ: British Medical Journal | 2019 | 10,984 |
| 3 | Diagnostic criteria for multiple sclerosis: 2010 Revisions to the McDonald criteria | Annals of Neurology | 2011 | 8,001 |
| 4 | Diagnostic criteria for multiple sclerosis: 2005 revisions to the “McDonald Criteria” | Annals of Neurology | 2005 | 4,495 |
| 5 | A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury | Nature Medicine | 2005 | 2,986 |
| 6 | Global, regional, and national causes of child mortality in 2008: a systematic analysis | Lancet, The | 2010 | 2,498 |
| 7 | Angiotensin-converting enzyme 2 protects from severe acute lung failure | Nature | 2005 | 2,264 |
| 8 | Colonic Health: Fermentation and Short Chain Fatty Acids | Journal of Clinical Gastroenterology | 2006 | 2,159 |
| 9 | Ventilator-Induced Lung Injury | New England Journal of Medicine | 2013 | 2,030 |
| 10 | SGLT2 inhibitors for primary and secondary prevention of cardiovascular and renal outcomes in type 2 diabetes: a systematic review and meta-analysis of cardiovascular outcome trials | Lancet, The | 2019 | 1,958 |
| 11 | Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma | JAMA - Journal of the American Medical Association | 2015 | 1,874 |
| 12 | Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19 | JAMA - Journal of the American Medical Association | 2020 | 1,855 |
| 13 | Selective head cooling with mild systemic hypothermia after neonatal encephalopathy: multicentre randomised trial | Lancet, The | 2005 | 1,827 |
| 14 | Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand | Nature | 1999 | 1,809 |
| 15 | Scoping reviews: time for clarity in definition, methods, and reporting | Journal of Clinical Epidemiology | 2014 | 1,766 |
| 16 | 2011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines | Annals of Thoracic Surgery | 2011 | 1,733 |
| 17 | Dulaglutide and cardiovascular outcomes in type 2 diabetes (REWIND): a double-blind, randomised placebo-controlled trial | Lancet, The | 2019 | 1,625 |
| 18 | The prevalence of Parkinson's disease: A systematic review and meta‐analysis | Movement Disorders | 2014 | 1,532 |
| 19 | Carotenoids and human health | Pharmacological Research | 2007 | 1,530 |
| 20 | Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome | Sleep Medicine | 2003 | 1,488 |
| 21 | No surgical innovation without evaluation: the IDEAL recommendations | Lancet, The | 2009 | 1,450 |
| 22 | Diagnostic criteria for hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber syndrome) | Lancet, The | 2000 | 1,391 |
| 23 | Platelets and the immune continuum | Nature Reviews Immunology | 2011 | 1,361 |
| 24 | Interventions for enhancing medication adherence | The Cochrane Library | 2014 | 1,352 |
| 25 | Diagnosis and Management of Complicated Intra-abdominal Infection in Adults and Children: Guidelines by the Surgical Infection Society and the Infectious Diseases Society of America | Clinical Infectious Diseases | 2010 | 1,260 |
| 26 | Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE) | BMJ: British Medical Journal | 2006 | 1,236 |
| 27 | The Surviving Sepsis Campaign: results of an international guideline-based performance improvement program targeting severe sepsis | Intensive Care Medicine | 2010 | 1,180 |
| 28 | Albiglutide and cardiovascular outcomes in patients with type 2 diabetes and cardiovascular disease (Harmony Outcomes): a double-blind, randomised placebo-controlled trial | Lancet, The | 2018 | 1,179 |
| 29 | Association of Colonoscopy and Death From Colorectal Cancer | Annals of Internal Medicine | 2009 | 1,106 |
| 30 | Statin-associated muscle symptoms: impact on statin therapy—European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management | European Heart Journal | 2015 | 1,024 |
| 31 | The glycemic index: methodology and clinical implications | American Journal of Clinical Nutrition | 1991 | 957 |
| 32 | A guide for the design and conduct of self-administered surveys of clinicians | Cmaj | 2008 | 947 |
| 33 | Transcatheter Aortic Valve Implantation for the Treatment of Severe Symptomatic Aortic Stenosis in Patients at Very High or Prohibitive Surgical Risk | Journal of the American College of Cardiology | 2010 | 929 |
| 34 | Not all patients want to participate in decision making | Journal of General Internal Medicine | 2005 | 927 |
| 35 | Intake of saturated and trans unsaturated fatty acids and risk of all cause mortality, cardiovascular disease, and type 2 diabetes: systematic review and meta-analysis of observational studies | BMJ, The | 2015 | 904 |
| 36 | Methods to estimate the between‐study variance and its uncertainty in meta‐analysis | Research Synthesis Methods | 2016 | 891 |
| 37 | International guidelines for the diagnosis and management of hereditary haemorrhagic telangiectasia | Journal of Medical Genetics | 2011 | 887 |
| 38 | Zika virus in the Americas: Early epidemiological and genetic findings | Science | 2016 | 877 |
| 39 | Cardiovascular health after maternal placental syndromes (CHAMPS): population-based retrospective cohort study | Lancet, The | 2005 | 873 |
| 40 | Assessment of the worldwide burden of critical illness: the Intensive Care Over Nations (ICON) audit | Lancet Respiratory Medicine,the | 2014 | 864 |
| 41 | Development, Validation, and Evaluation of a Pediatric Ulcerative Colitis Activity Index: A Prospective Multicenter Study | Gastroenterology | 2007 | 847 |
| 42 | Efficacy and safety of the elexacaftor plus tezacaftor plus ivacaftor combination regimen in people with cystic fibrosis homozygous for the F508del mutation: a double-blind, randomised, phase 3 trial | Lancet, The | 2019 | 804 |
| 43 | Ovarian cancer screening and mortality in the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS): a randomised controlled trial | Lancet, The | 2016 | 791 |
| 44 | 2016 Canadian Cardiovascular Society Guidelines for the Management of Dyslipidemia for the Prevention of Cardiovascular Disease in the Adult | Canadian Journal of Cardiology | 2016 | 775 |
| 45 | Titration and Implementation of Neurally Adjusted Ventilatory Assist in Critically Ill Patients | Chest | 2009 | 736 |
| 46 | Amiodarone as Compared with Lidocaine for Shock-Resistant Ventricular Fibrillation | New England Journal of Medicine | 2002 | 730 |
| 47 | Inspiratory Muscle Unloading by Neurally Adjusted Ventilatory Assist During Maximal Inspiratory Efforts in Healthy Subjects | Chest | 2007 | 729 |
| 48 | Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene | Journal of Biological Chemistry | 1993 | 727 |
| 49 | Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection | Journal of Experimental Medicine | 2008 | 681 |
| 50 | Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19 | JAMA - Journal of the American Medical Association | 2020 | 671 |
