| # | Title | Journal | Year | Citations |
|---|
| 1 | Signatures of mutational processes in human cancer | Nature | 2013 | 8,060 |
| 2 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease | New England Journal of Medicine | 2017 | 4,179 |
| 5 | Biological properties of extracellular vesicles and their physiological functions | Journal of Extracellular Vesicles | 2015 | 3,973 |
| 6 | Photodynamic therapy of cancer: An update | Ca-A Cancer Journal for Clinicians | 2011 | 3,902 |
| 7 | Tumour exosome integrins determine organotropic metastasis | Nature | 2015 | 3,688 |
| 8 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 9 | ALKBH5 Is a Mammalian RNA Demethylase that Impacts RNA Metabolism and Mouse Fertility | Molecular Cell | 2013 | 2,549 |
| 10 | Liver Fibrosis, but No Other Histologic Features, Is Associated With Long-term Outcomes of Patients With Nonalcoholic Fatty Liver Disease | Gastroenterology | 2015 | 2,200 |
| 11 | 2018 ESC/ESH Guidelines for the management of arterial hypertension | Journal of Hypertension | 2018 | 2,129 |
| 12 | Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver | Nature Cell Biology | 2015 | 2,064 |
| 13 | Consensus statement on concussion in sport—the 5thinternational conference on concussion in sport held in Berlin, October 2016 | British Journal of Sports Medicine | 2017 | 1,903 |
| 14 | A Phase 3 Trial of Bevacizumab in Ovarian Cancer | New England Journal of Medicine | 2011 | 1,843 |
| 15 | Pembrolizumab alone or with chemotherapy versus cetuximab with chemotherapy for recurrent or metastatic squamous cell carcinoma of the head and neck (KEYNOTE-048): a randomised, open-label, phase 3 study | Lancet, The | 2019 | 1,804 |
| 16 | Landscape of somatic mutations in 560 breast cancer whole-genome sequences | Nature | 2016 | 1,760 |
| 17 | Consensus statement on concussion in sport: the 4th International Conference on Concussion in Sport held in Zurich, November 2012 | British Journal of Sports Medicine | 2013 | 1,744 |
| 18 | Current knowledge on exosome biogenesis and release | Cellular and Molecular Life Sciences | 2018 | 1,689 |
| 19 | Comprehensive genomic profiles of small cell lung cancer | Nature | 2015 | 1,634 |
| 20 | Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk | Nature Genetics | 2019 | 1,625 |
| 21 | Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder | Nature Genetics | 2019 | 1,594 |
| 22 | The landscape of cancer genes and mutational processes in breast cancer | Nature | 2012 | 1,535 |
| 23 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 24 | Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies | Lancet Neurology, The | 2019 | 1,414 |
| 25 | Patient-Derived Xenograft Models: An Emerging Platform for Translational Cancer Research | Cancer Discovery | 2014 | 1,341 |
| 26 | Association studies of up to 1.2 million individuals yield new insights into the genetic etiology of tobacco and alcohol use | Nature Genetics | 2019 | 1,307 |
| 27 | The Oslo definitions for coeliac disease and related terms | Gut | 2013 | 1,300 |
| 28 | Recommendations for the echocardiographic assessment of native valvular regurgitation: an executive summary from the European Association of Cardiovascular Imaging | European Heart Journal Cardiovascular Imaging | 2013 | 1,298 |
| 29 | The Life History of 21 Breast Cancers | Cell | 2012 | 1,249 |
| 30 | Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines—2016 revision | Journal of Allergy and Clinical Immunology | 2017 | 1,199 |
| 31 | Genome-wide association study identifies 30 loci associated with bipolar disorder | Nature Genetics | 2019 | 1,191 |
| 32 | Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer | Nature Genetics | 2012 | 1,186 |
| 33 | Predictive Value of the sFlt-1:PlGF Ratio in Women with Suspected Preeclampsia | New England Journal of Medicine | 2016 | 1,158 |
| 34 | Thrombosis and Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination | New England Journal of Medicine | 2021 | 1,155 |
| 35 | Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture | Nature Genetics | 2012 | 1,100 |
| 36 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 37 | Vesiclepedia: A Compendium for Extracellular Vesicles with Continuous Community Annotation | PLoS Biology | 2012 | 1,064 |
| 38 | Expert Consensus for Multimodality Imaging Evaluation of Adult Patients during and after Cancer Therapy: A Report from the American Society of Echocardiography and the European Association of Cardiovascular Imaging | Journal of the American Society of Echocardiography | 2014 | 1,051 |
| 39 | Diagnosis and management of primary sclerosing cholangitis | Hepatology | 2010 | 1,048 |
| 40 | Allele-specific copy number analysis of tumors | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 979 |
| 41 | Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) | Nature Reviews Gastroenterology and Hepatology | 2016 | 964 |
| 42 | European Resuscitation Council Guidelines for Resuscitation 2015 | Resuscitation | 2015 | 937 |
| 43 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 44 | Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer | New England Journal of Medicine | 2019 | 918 |
| 45 | Base Excision Repair | Cold Spring Harbor Perspectives in Biology | 2013 | 908 |
| 46 | Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence | Nature Genetics | 2018 | 893 |
| 47 | Standardization of left atrial, right ventricular, and right atrial deformation imaging using two-dimensional speckle tracking echocardiography: a consensus document of the EACVI/ASE/Industry Task Force to standardize deformation imaging | European Heart Journal Cardiovascular Imaging | 2018 | 891 |
| 48 | Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial | Lancet Oncology, The | 2017 | 889 |
| 49 | European Resuscitation Council and European Society of Intensive Care Medicine Guidelines for Post-resuscitation Care 2015 | Resuscitation | 2015 | 850 |
| 50 | Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis | Lancet, The | 2012 | 847 |
