# | Title | Journal | Year | Citations |
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1 | ISB recommendation on definitions of joint coordinate system of various joints for the reporting of human joint motion—part I: ankle, hip, and spine | Journal of Biomechanics | 2002 | 2,491 |
2 | The Simons Genome Diversity Project: 300 genomes from 142 diverse populations | Nature | 2016 | 1,216 |
3 | Pharmacogenomics and metabolite measurement for 6-mercaptopurine therapy in inflammatory bowel disease | Gastroenterology | 2000 | 989 |
4 | A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increasedAkkermansiaspp. population in the gut microbiota of mice | Gut | 2015 | 910 |
5 | Thrombophilic disorders and fetal loss: a meta-analysis | Lancet, The | 2003 | 809 |
6 | Symmetry and limb dominance in able-bodied gait: a review | Gait and Posture | 2000 | 758 |
7 | Validation of the paediatric logistic organ dysfunction (PELOD) score: prospective, observational, multicentre study | Lancet, The | 2003 | 654 |
8 | Consensus Statement on the Diagnosis and Treatment of Children with Idiopathic Short Stature: A Summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop | Journal of Clinical Endocrinology and Metabolism | 2008 | 571 |
9 | Childhood Functional Gastrointestinal Disorders: Neonate/Toddler | Gastroenterology | 2016 | 550 |
10 | Diagnostic Testing for Severe Acute Respiratory Syndrome–Related Coronavirus 2 | Annals of Internal Medicine | 2020 | 517 |
11 | Meta-analysis of SHANK Mutations in Autism Spectrum Disorders: A Gradient of Severity in Cognitive Impairments | PLoS Genetics | 2014 | 501 |
12 | Seizures and Epilepsy: An Overview for Neuroscientists | Cold Spring Harbor Perspectives in Medicine | 2015 | 486 |
13 | The impact of COVID-19 on pregnancy outcomes: a systematic review and meta-analysis | Cmaj | 2021 | 478 |
14 | Hypertension Canada’s 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2018 | 474 |
15 | Genetic Variation and Population Structure in Native Americans | PLoS Genetics | 2007 | 454 |
16 | An international consensus approach to the management of atypical hemolytic uremic syndrome in children | Pediatric Nephrology | 2016 | 445 |
17 | PELOD-2 | Critical Care Medicine | 2013 | 431 |
18 | The 2015 Canadian Hypertension Education Program Recommendations for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension | Canadian Journal of Cardiology | 2015 | 431 |
19 | DNA-SCARS: distinct nuclear structures that sustain damage-induced senescence growth arrest and inflammatory cytokine secretion | Journal of Cell Science | 2011 | 413 |
20 | Accuracy of Rapid Influenza Diagnostic Tests | Annals of Internal Medicine | 2012 | 408 |
21 | European Society for Paediatric Endocrinology Consensus Guidelines on Screening, Diagnosis, and Management of Congenital Hypothyroidism | Journal of Clinical Endocrinology and Metabolism | 2014 | 403 |
22 | Early cytomegalovirus reactivation remains associated with increased transplant-related mortality in the current era: a CIBMTR analysis | Blood | 2016 | 403 |
23 | Hypertension Canada's 2016 Canadian Hypertension Education Program Guidelines for Blood Pressure Measurement, Diagnosis, Assessment of Risk, Prevention, and Treatment of Hypertension | Canadian Journal of Cardiology | 2016 | 400 |
24 | Genetic mechanisms of target antigen loss in CAR19 therapy of acute lymphoblastic leukemia | Nature Medicine | 2018 | 393 |
25 | Hematopoietic Stem-Cell Transplantation for Acute Leukemia in Relapse or Primary Induction Failure | Journal of Clinical Oncology | 2010 | 386 |
26 | Assessment of dexrazoxane as a cardioprotectant in doxorubicin-treated children with high-risk acute lymphoblastic leukaemia: long-term follow-up of a prospective, randomised, multicentre trial | Lancet Oncology, The | 2010 | 377 |
27 | Noncoding regions are the main source of targetable tumor-specific antigens | Science Translational Medicine | 2018 | 374 |
28 | Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia | Blood | 2007 | 362 |
29 | De novo mutations in the gene encoding the synaptic scaffolding proteinSHANK3in patients ascertained for schizophrenia | Proceedings of the National Academy of Sciences of the United States of America | 2010 | 361 |
30 | p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes | Journal of Cell Biology | 2013 | 344 |
31 | Neutrophils: Cinderella of innate immune system | International Immunopharmacology | 2010 | 343 |
32 | Epidemiology of Sepsis and Multiple Organ Dysfunction Syndrome in Children | Chest | 1996 | 339 |
33 | Sequence Analysis and Homology Modeling Suggest That Primary Congenital Glaucoma on 2p21 Results from Mutations Disrupting Either the Hinge Region or the Conserved Core Structures of Cytochrome P4501B1 | American Journal of Human Genetics | 1998 | 327 |
34 | Mutability of Y-Chromosomal Microsatellites: Rates, Characteristics, Molecular Bases, and Forensic Implications | American Journal of Human Genetics | 2010 | 324 |
35 | Hypertension Canada’s 2020 Comprehensive Guidelines for the Prevention, Diagnosis, Risk Assessment, and Treatment of Hypertension in Adults and Children | Canadian Journal of Cardiology | 2020 | 324 |
36 | Clinical similarities and differences of patients with X-linked lymphoproliferative syndrome type 1 (XLP-1/SAP deficiency) versus type 2 (XLP-2/XIAP deficiency) | Blood | 2011 | 320 |
37 | 2011 SOSORT guidelines: Orthopaedic and Rehabilitation treatment of idiopathic scoliosis during growth | Scoliosis | 2012 | 316 |
38 | Diagnostic Imaging of Spinal Deformities | Spine | 2010 | 302 |
39 | Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study | Blood | 2011 | 296 |
40 | Acute kidney injury is an independent risk factor for pediatric intensive care unit mortality, longer length of stay and prolonged mechanical ventilation in critically ill children: a two-center retrospective cohort study | Critical Care | 2011 | 294 |
41 | Novel de novo SHANK3 mutation in autistic patients | American Journal of Medical Genetics Part B: Neuropsychiatric Genetics | 2009 | 289 |
42 | Growth Hormone Research Society Workshop Summary: Consensus Guidelines for Recombinant Human Growth Hormone Therapy in Prader-Willi Syndrome | Journal of Clinical Endocrinology and Metabolism | 2013 | 288 |
43 | Genome-wide analysis of transcript isoform variation in humans | Nature Genetics | 2008 | 283 |
44 | Preemptive Use of High-Dose Fluticasone for Virus-Induced Wheezing in Young Children | New England Journal of Medicine | 2009 | 283 |
45 | ESPGHAN‐NASPGHAN Guidelines for the Evaluation and Treatment of Gastrointestinal and Nutritional Complications in Children With Esophageal Atresia‐Tracheoesophageal Fistula | Journal of Pediatric Gastroenterology and Nutrition | 2016 | 277 |
46 | Prognostic value of medulloblastoma extent of resection after accounting for molecular subgroup: a retrospective integrated clinical and molecular analysis | Lancet Oncology, The | 2016 | 274 |
47 | Hypertension Canada's 2017 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults | Canadian Journal of Cardiology | 2017 | 269 |
48 | Paediatric acute respiratory distress syndrome incidence and epidemiology (PARDIE): an international, observational study | Lancet Respiratory Medicine,the | 2019 | 267 |
49 | Direct correlation between the load of Epstein-Barr virus-infected lymphocytes in the peripheral blood of pediatric transplant patients and risk of lymphoproliferative disease | Blood | 1994 | 265 |
50 | Allele-Specific Chromatin Remodeling in the ZPBP2/GSDMB/ORMDL3 Locus Associated with the Risk of Asthma and Autoimmune Disease | American Journal of Human Genetics | 2009 | 262 |