| # | Title | Journal | Year | Citations |
|---|
|
| 1 | Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness | Scientific Reports | 2017 | 26,615 |
| 2 | Ror2 signaling regulates Golgi structure and transport through IFT20 for tumor invasiveness | Scientific Reports | 2017 | 26,615 |
| 3 | Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology | Genetics in Medicine | 2015 | 22,146 |
| 4 | Model-based Analysis of ChIP-Seq (MACS) | Genome Biology | 2008 | 14,393 |
| 5 | The Amyloid Hypothesis of Alzheimer's Disease: Progress and Problems on the Road to Therapeutics | Science | 2002 | 12,318 |
| 6 | A method and server for predicting damaging missense mutations | Nature Methods | 2010 | 11,805 |
| 7 | Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 11,297 |
| 8 | 2015 American Thyroid Association Management Guidelines for Adult Patients with Thyroid Nodules and Differentiated Thyroid Cancer: The American Thyroid Association Guidelines Task Force on Thyroid Nodules and Differentiated Thyroid Cancer | Thyroid | 2016 | 11,291 |
| 9 | Bioconductor: open software development for computational biology and bioinformatics | Genome Biology | 2004 | 10,980 |
| 10 | Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance | Clinical Microbiology and Infection | 2012 | 9,616 |
| 11 | EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy | Science | 2004 | 9,112 |
| 12 | Principal components analysis corrects for stratification in genome-wide association studies | Nature Genetics | 2006 | 9,097 |
| 13 | PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes | Nature Genetics | 2003 | 8,581 |
| 14 | Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine | New England Journal of Medicine | 2021 | 8,423 |
| 15 | Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine | New England Journal of Medicine | 2021 | 8,423 |
| 16 | Signatures of mutational processes in human cancer | Nature | 2013 | 8,334 |
| 17 | Nanocarriers as an emerging platform for cancer therapy | Nature Nanotechnology | 2007 | 7,609 |
| 18 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 7,596 |
| 19 | Inflammation in atherosclerosis | Nature | 2002 | 7,427 |
| 20 | Disability-adjusted life years (DALYs) for 291 diseases and injuries in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 7,201 |
| 21 | The Effect of Pravastatin on Coronary Events after Myocardial Infarction in Patients with Average Cholesterol Levels | New England Journal of Medicine | 1996 | 7,099 |
| 22 | 2010 Rheumatoid arthritis classification criteria: An American College of Rheumatology/European League Against Rheumatism collaborative initiative | Arthritis and Rheumatism | 2010 | 7,062 |
| 23 | Effects of Losartan on Renal and Cardiovascular Outcomes in Patients with Type 2 Diabetes and Nephropathy | New England Journal of Medicine | 2001 | 6,691 |
| 24 | Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease | New England Journal of Medicine | 2017 | 6,669 |
| 25 | Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease | New England Journal of Medicine | 2017 | 6,669 |
| 26 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,546 |
| 27 | NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease | Alzheimer's and Dementia | 2018 | 6,501 |
| 28 | Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells | Nature | 2006 | 6,438 |
| 29 | Effect of physical inactivity on major non-communicable diseases worldwide: an analysis of burden of disease and life expectancy | Lancet, The | 2012 | 6,359 |
| 30 | Food in the Anthropocene: the EAT–Lancet Commission on healthy diets from sustainable food systems | Lancet, The | 2019 | 6,086 |
| 31 | Prasugrel versus Clopidogrel in Patients with Acute Coronary Syndromes | New England Journal of Medicine | 2007 | 6,024 |
| 32 | Guidelines for the Echocardiographic Assessment of the Right Heart in Adults: A Report from the American Society of Echocardiography | Journal of the American Society of Echocardiography | 2010 | 5,930 |
| 33 | Integrative analysis of 111 reference human epigenomes | Nature | 2015 | 5,866 |
| 34 | Rosuvastatin to Prevent Vascular Events in Men and Women with Elevated C-Reactive Protein | New England Journal of Medicine | 2008 | 5,843 |
| 35 | Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging‐Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease | Alzheimer's and Dementia | 2011 | 5,740 |
| 36 | 3D Slicer as an image computing platform for the Quantitative Imaging Network | Magnetic Resonance Imaging | 2012 | 5,656 |
| 37 | Effect of Captopril on Mortality and Morbidity in Patients with Left Ventricular Dysfunction after Myocardial Infarction | New England Journal of Medicine | 1992 | 5,601 |
| 38 | Alzheimer's Disease: Genes, Proteins, and Therapy | Physiological Reviews | 2001 | 5,526 |
| 39 | Endothelial cell infection and endotheliitis in COVID-19 | Lancet, The | 2020 | 5,320 |
| 40 | Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure | New England Journal of Medicine | 2014 | 5,309 |
| 41 | Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus | Nature | 2003 | 5,297 |
| 42 | C-Reactive Protein and Other Markers of Inflammation in the Prediction of Cardiovascular Disease in Women | New England Journal of Medicine | 2000 | 5,270 |
| 43 | Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma | New England Journal of Medicine | 1991 | 5,258 |
| 44 | Modeling the Shape of the Scene: A Holistic Representation of the Spatial Envelope | International Journal of Computer Vision | 2001 | 5,254 |
| 45 | Modeling the Shape of the Scene: A Holistic Representation of the Spatial Envelope | International Journal of Computer Vision | 2001 | 5,254 |
| 46 | Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus | Gut | 2013 | 5,102 |
| 47 | Classification of acute pancreatitis—2012: revision of the Atlanta classification and definitions by international consensus | Gut | 2013 | 5,102 |
| 48 | Inflammation, Aspirin, and the Risk of Cardiovascular Disease in Apparently Healthy Men | New England Journal of Medicine | 1997 | 5,056 |
| 49 | Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma | New England Journal of Medicine | 2015 | 5,039 |
| 50 | Development and Validation of a Deep Learning Algorithm for Detection of Diabetic Retinopathy in Retinal Fundus Photographs | JAMA - Journal of the American Medical Association | 2016 | 5,033 |
