# | Title | Journal | Year | Citations |
---|
1 | Model-based Analysis of ChIP-Seq (MACS) | Genome Biology | 2008 | 13,517 |
2 | A Neural Substrate of Prediction and Reward | Science | 1997 | 7,899 |
3 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
4 | The Cancer Genome Atlas Pan-Cancer analysis project | Nature Genetics | 2013 | 6,265 |
5 | Sequencing technologies — the next generation | Nature Reviews Genetics | 2010 | 5,942 |
6 | Development of a Dual-Index Sequencing Strategy and Curation Pipeline for Analyzing Amplicon Sequence Data on the MiSeq Illumina Sequencing Platform | Applied and Environmental Microbiology | 2013 | 5,923 |
7 | Integrative analysis of 111 reference human epigenomes | Nature | 2015 | 5,653 |
8 | The Genome Sequence of Drosophila melanogaster | Science | 2000 | 5,566 |
9 | The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases | Cell | 1993 | 5,487 |
10 | Genome-wide atlas of gene expression in the adult mouse brain | Nature | 2007 | 4,863 |
11 | Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis | Gastroenterology | 2007 | 4,828 |
12 | Movement Disorder Society‐sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS‐UPDRS): Scale presentation and clinimetric testing results | Movement Disorders | 2008 | 4,796 |
13 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
14 | Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2 | Nature Genetics | 1999 | 4,459 |
15 | Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours | Nature | 1992 | 4,446 |
16 | UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses | Neoplasia | 2017 | 4,166 |
17 | Current Concepts in Mild Cognitive Impairment | Archives of Neurology | 2001 | 4,117 |
18 | Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix | Acta Crystallographica Section D: Structural Biology | 2019 | 4,060 |
19 | The Somatic Genomic Landscape of Glioblastoma | Cell | 2013 | 3,979 |
20 | Parkinson's disease: clinical features and diagnosis | Journal of Neurology, Neurosurgery and Psychiatry | 2008 | 3,887 |
21 | Expert Committee Recommendations Regarding the Prevention, Assessment, and Treatment of Child and Adolescent Overweight and Obesity: Summary Report | Pediatrics | 2007 | 3,779 |
22 | Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses | Science | 2008 | 3,755 |
23 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
24 | Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin | Nature | 2000 | 3,524 |
25 | Hepatocellular Carcinoma | New England Journal of Medicine | 2011 | 3,427 |
26 | Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion | Cell | 2005 | 3,273 |
27 | Biological, clinical and population relevance of 95 loci for blood lipids | Nature | 2010 | 3,249 |
28 | Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy | Cell | 2005 | 3,204 |
29 | Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients | Science | 2018 | 3,126 |
30 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
31 | Regulation of p53 stability by Mdm2 | Nature | 1997 | 3,054 |
32 | Distribution of repetitive DNA sequences in eubacteria and application to finerpriting of bacterial enomes | Nucleic Acids Research | 1991 | 3,006 |
33 | The DNA damage response: putting checkpoints in perspective | Nature | 2000 | 2,922 |
34 | EMAN2: An extensible image processing suite for electron microscopy | Journal of Structural Biology | 2007 | 2,798 |
35 | Molecular Mechanisms of Action of Steroid/Thyroid Receptor Superfamily Members | Annual Review of Biochemistry | 1994 | 2,795 |
36 | Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma | Gastroenterology | 2012 | 2,753 |
37 | Identification of the von Hippel-Lindau disease tumor suppressor gene | Science | 1993 | 2,723 |
38 | Doppler Tissue Imaging: A Noninvasive Technique for Evaluation of Left Ventricular Relaxation and Estimation of Filling Pressures | Journal of the American College of Cardiology | 1997 | 2,720 |
39 | Global, Regional, and National Burden of Cardiovascular Diseases for 10 Causes, 1990 to 2015 | Journal of the American College of Cardiology | 2017 | 2,705 |
40 | Genomic analyses identify molecular subtypes of pancreatic cancer | Nature | 2016 | 2,700 |
41 | Somatic mutations affect key pathways in lung adenocarcinoma | Nature | 2008 | 2,694 |
42 | Clinical Practice Guidelines by the Infectious Diseases Society of America for the Treatment of Methicillin-Resistant Staphylococcus aureus Infections in Adults and Children | Clinical Infectious Diseases | 2011 | 2,673 |
43 | American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer | Journal of Clinical Oncology | 2010 | 2,667 |
44 | The Definition and Classification of Dry Eye Disease: Report of the Definition and Classification Subcommittee of the International Dry Eye Workshop (2007) | Ocular Surface | 2007 | 2,650 |
45 | Microbiota Modulate Behavioral and Physiological Abnormalities Associated with Neurodevelopmental Disorders | Cell | 2013 | 2,596 |
46 | A Comparison of Continuous Intravenous Epoprostenol (Prostacyclin) with Conventional Therapy for Primary Pulmonary Hypertension | New England Journal of Medicine | 1996 | 2,529 |
47 | TFEB Links Autophagy to Lysosomal Biogenesis | Science | 2011 | 2,513 |
48 | EMAN: Semiautomated Software for High-Resolution Single-Particle Reconstructions | Journal of Structural Biology | 1999 | 2,320 |
49 | Cardiovascular Effects of Intensive Lifestyle Intervention in Type 2 Diabetes | New England Journal of Medicine | 2013 | 2,294 |
50 | Sequence and Characterization of a Coactivator for the Steroid Hormone Receptor Superfamily | Science | 1995 | 2,271 |