| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma | Lancet Oncology, The | 2014 | 3,343 |
| 3 | International Myeloma Working Group consensus criteria for response and minimal residual disease assessment in multiple myeloma | Lancet Oncology, The | 2016 | 1,866 |
| 4 | 2016 American Thyroid Association Guidelines for Diagnosis and Management of Hyperthyroidism and Other Causes of Thyrotoxicosis | Thyroid | 2016 | 1,757 |
| 5 | EICOSAPENTAENOIC ACID AND PREVENTION OF THROMBOSIS AND ATHEROSCLEROSIS? | Lancet, The | 1978 | 1,494 |
| 6 | ESPEN guidelines on definitions and terminology of clinical nutrition | Clinical Nutrition | 2017 | 1,451 |
| 7 | Defibrillator Implantation in Patients with Nonischemic Systolic Heart Failure | New England Journal of Medicine | 2016 | 1,350 |
| 8 | Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer | New England Journal of Medicine | 2019 | 1,337 |
| 9 | Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper | Journal of Extracellular Vesicles | 2015 | 1,020 |
| 10 | Neuropathologic diagnostic and nosologic criteria for frontotemporal lobar degeneration: consensus of the Consortium for Frontotemporal Lobar Degeneration | Acta Neuropathologica | 2007 | 978 |
| 11 | HÆMOSTATIC FUNCTION AND PLATELET POLYUNSATURATED FATTY ACIDS IN ESKIMOS | Lancet, The | 1979 | 875 |
| 12 | Sensitization in patients with painful knee osteoarthritis | Pain | 2010 | 785 |
| 13 | Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial | Lancet, The | 2015 | 748 |
| 14 | ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment | Journal of Crohn's and Colitis | 2020 | 741 |
| 15 | Comparative efficacy and tolerability of medications for attention-deficit hyperactivity disorder in children, adolescents, and adults: a systematic review and network meta-analysis | Lancet Psychiatry,the | 2018 | 722 |
| 16 | Percutaneous coronary angioplasty versus coronary artery bypass grafting in treatment of unprotected left main stenosis (NOBLE): a prospective, randomised, open-label, non-inferiority trial | Lancet, The | 2016 | 620 |
| 17 | Ultrasonic Echolucent Carotid Plaques Predict Future Strokes | Circulation | 2001 | 615 |
| 18 | Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study | BMJ: British Medical Journal | 2005 | 614 |
| 19 | Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer | Nature Genetics | 2009 | 597 |
| 20 | MYC/BCL2 protein coexpression contributes to the inferior survival of activated B-cell subtype of diffuse large B-cell lymphoma and demonstrates high-risk gene expression signatures: a report from The International DLBCL Rituximab-CHOP Consortium Program | Blood | 2013 | 596 |
| 21 | Implant-based multiparameter telemonitoring of patients with heart failure (IN-TIME): a randomised controlled trial | Lancet, The | 2014 | 594 |
| 22 | Small Differences in Thyroid Function May Be Important for Body Mass Index and the Occurrence of Obesity in the Population | Journal of Clinical Endocrinology and Metabolism | 2005 | 593 |
| 23 | Narrow Individual Variations in Serum T4and T3in Normal Subjects: A Clue to the Understanding of Subclinical Thyroid Disease | Journal of Clinical Endocrinology and Metabolism | 2002 | 576 |
| 24 | Incidence and Late Prognosis of Cushing’s Syndrome: A Population-Based Study1 | Journal of Clinical Endocrinology and Metabolism | 2001 | 533 |
| 25 | Study design, exposure variables, and socioeconomic determinants of participation in Diet, Cancer and Health: A population-based prospective cohort study of 57,053 men and women in Denmark | Scandinavian Journal of Public Health | 2007 | 532 |
| 26 | Miscarriage matters: the epidemiological, physical, psychological, and economic costs of early pregnancy loss | Lancet, The | 2021 | 508 |
| 27 | A Randomized, Controlled Trial of Total Knee Replacement | New England Journal of Medicine | 2015 | 498 |
| 28 | ESHRE guideline: recurrent pregnancy loss | Human Reproduction Open | 2018 | 498 |
| 29 | Assessment of 68Ga-PSMA-11 PET Accuracy in Localizing Recurrent Prostate Cancer | JAMA Oncology | 2019 | 493 |
| 30 | Comprehensive Transcriptional Analysis of Early-Stage Urothelial Carcinoma | Cancer Cell | 2016 | 486 |
| 31 | ECCO Guidelines on Therapeutics in Crohn’s Disease: Surgical Treatment | Journal of Crohn's and Colitis | 2020 | 478 |
| 32 | ESPEN endorsed recommendations. Definition and classification of intestinal failure in adults | Clinical Nutrition | 2015 | 473 |
| 33 | Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure | Nature Communications | 2020 | 466 |
| 34 | Cardiovascular effects of marine omega-3 fatty acids | Lancet, The | 2010 | 450 |
| 35 | TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin Inclusions | American Journal of Pathology | 2007 | 446 |
| 36 | High-dose chemoradiotherapy and watchful waiting for distal rectal cancer: a prospective observational study | Lancet Oncology, The | 2015 | 435 |
| 37 | Outcomes in Type 1 Diabetic Pregnancies: A nationwide, population-based study | Diabetes Care | 2004 | 424 |
| 38 | Increased Short- and Long-Term Risk of Inflammatory Bowel Disease After Salmonella or Campylobacter Gastroenteritis | Gastroenterology | 2009 | 419 |
| 39 | Reproducibility of histomorphologic diagnoses with special reference to the kappa statistic | Apmis | 1989 | 413 |
| 40 | Individualised therapy is more cost-effective than dose intensification in patients with Crohn’s disease who lose response to anti-TNF treatment: a randomised, controlled trial | Gut | 2014 | 413 |
| 41 | Assessment and manifestation of central sensitisation across different chronic pain conditions | European Journal of Pain | 2018 | 411 |
| 42 | Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database | Nature Genetics | 2014 | 410 |
| 43 | Cancer risk and survival in path_MMR carriers by gene and gender up to 75 years of age: a report from the Prospective Lynch Syndrome Database | Gut | 2018 | 410 |
| 44 | National Clinical Guidelines for non-surgical treatment of patients with recent onset low back pain or lumbar radiculopathy | European Spine Journal | 2018 | 403 |
| 45 | Incidence of central post-stroke pain | Pain | 1995 | 393 |
| 46 | Association of Type and Location ofBRCA1andBRCA2Mutations With Risk of Breast and Ovarian Cancer | JAMA - Journal of the American Medical Association | 2015 | 390 |
| 47 | Efficacy and Safety of Dabigatran Etexilate and Warfarin in “Real-World” Patients With Atrial Fibrillation | Journal of the American College of Cardiology | 2013 | 387 |
| 48 | Mortality Attributable to Smoking Among HIV-1–Infected Individuals: A Nationwide, Population-Based Cohort Study | Clinical Infectious Diseases | 2013 | 384 |
| 49 | MicroRNA Biomarkers in Whole Blood for Detection of Pancreatic Cancer | JAMA - Journal of the American Medical Association | 2014 | 380 |
| 50 | Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations | Acta Neuropathologica | 2009 | 377 |
