| # | Title | Journal | Year | Citations |
|---|
| 1 | Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus | Lancet, The | 1998 | 2,268 |
| 2 | Sunitinib Malate for the Treatment of Pancreatic Neuroendocrine Tumors | New England Journal of Medicine | 2011 | 2,216 |
| 3 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,211 |
| 4 | Phase 3 Trial of 177Lu-Dotatate for Midgut Neuroendocrine Tumors | New England Journal of Medicine | 2017 | 2,206 |
| 5 | Predicting survival after liver transplantation in patients with hepatocellular carcinoma beyond the Milan criteria: a retrospective, exploratory analysis | Lancet Oncology, The | 2009 | 1,920 |
| 6 | Clinical classification of pulmonary hypertension | Journal of the American College of Cardiology | 2004 | 1,542 |
| 7 | Regression of cirrhosis during treatment with tenofovir disoproxil fumarate for chronic hepatitis B: a 5-year open-label follow-up study | Lancet, The | 2013 | 1,476 |
| 8 | Comparison of adjuvant gemcitabine and capecitabine with gemcitabine monotherapy in patients with resected pancreatic cancer (ESPAC-4): a multicentre, open-label, randomised, phase 3 trial | Lancet, The | 2017 | 1,475 |
| 9 | Gastroenteropancreatic neuroendocrine tumours | Lancet Oncology, The | 2008 | 1,474 |
| 10 | TNM staging of foregut (neuro)endocrine tumors: a consensus proposal including a grading system | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2006 | 1,403 |
| 11 | The International Position on Laparoscopic Liver Surgery | Annals of Surgery | 2009 | 1,325 |
| 12 | Noninvasive assessment of liver fibrosis by measurement of stiffness in patients with chronic hepatitis C | Hepatology | 2005 | 1,276 |
| 13 | Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma | Nature Genetics | 2012 | 1,229 |
| 14 | The burden of liver disease in Europe: A review of available epidemiological data | Journal of Hepatology | 2013 | 1,089 |
| 15 | Peginterferon Alfa-2a Alone, Lamivudine Alone, and the Two in Combination in Patients with HBeAg-Negative Chronic Hepatitis B | New England Journal of Medicine | 2004 | 1,082 |
| 16 | Mechanisms of Hepatotoxicity | Toxicological Sciences | 2002 | 1,043 |
| 17 | Etomidate versus ketamine for rapid sequence intubation in acutely ill patients: a multicentre randomised controlled trial | Lancet, The | 2009 | 995 |
| 18 | Seven hundred forty-seven hepatectomies in the 1990s: an update to evaluate the actual risk of liver resection11No competing interests declared. | Journal of the American College of Surgeons | 2000 | 985 |
| 19 | Practices of Liver Biopsy in France: Results of a Prospective Nationwide Survey | Hepatology | 2000 | 897 |
| 20 | The ???50-50 Criteria??? on Postoperative Day 5 | Annals of Surgery | 2005 | 878 |
| 21 | TNM staging of midgut and hindgut (neuro) endocrine tumors: a consensus proposal including a grading system | Virchows Archiv Fur Pathologische Anatomie Und Physiologie Und Fur Klinische Medizin | 2007 | 877 |
| 22 | Elafibranor, an Agonist of the Peroxisome Proliferator−Activated Receptor−α and −δ, Induces Resolution of Nonalcoholic Steatohepatitis Without Fibrosis Worsening | Gastroenterology | 2016 | 847 |
| 23 | Long-term Therapy With Adefovir Dipivoxil for HBeAg-Negative Chronic Hepatitis B for up to 5 Years | Gastroenterology | 2006 | 832 |
| 24 | Organ-Specific Disease Provoked by Systemic Autoimmunity | Cell | 1996 | 828 |
| 25 | Obeticholic acid for the treatment of non-alcoholic steatohepatitis: interim analysis from a multicentre, randomised, placebo-controlled phase 3 trial | Lancet, The | 2019 | 818 |
| 26 | Vascular disorders of the liver | Hepatology | 2009 | 805 |
| 27 | Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19 | Journal of Infection | 2020 | 767 |
| 28 | Radiographic Analysis of the Sagittal Alignment and Balance of the Spine in Asymptomatic Subjects | Journal of Bone and Joint Surgery - Series A | 2005 | 759 |
| 29 | The management of ascites in cirrhosis: Report on the consensus conference of the International Ascites Club | Hepatology | 2003 | 744 |
| 30 | Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure | Journal of Hepatology | 2014 | 741 |
| 31 | ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment | Journal of Crohn's and Colitis | 2020 | 741 |
| 32 | Individual patient data meta-analysis of controlled attenuation parameter (CAP) technology for assessing steatosis | Journal of Hepatology | 2017 | 734 |
| 33 | A Bedside Ultrasound Sign Ruling Out Pneumothorax in the Critically III | Chest | 1995 | 721 |
| 34 | Liver hanging maneuver: a safe approach to right hepatectomy without liver mobilization | Journal of the American College of Surgeons | 2001 | 717 |
| 35 | Controlled Attenuation Parameter (CAP): A Novel VCTE™ Guided Ultrasonic Attenuation Measurement for the Evaluation of Hepatic Steatosis: Preliminary Study and Validation in a Cohort of Patients with Chronic Liver Disease from Various Causes | Ultrasound in Medicine and Biology | 2010 | 683 |
| 36 | Sunitinib Versus Sorafenib in Advanced Hepatocellular Cancer: Results of a Randomized Phase III Trial | Journal of Clinical Oncology | 2013 | 678 |
| 37 | EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long Version) | Ultraschall in Der Medizin | 2017 | 659 |
| 38 | Histopathological algorithm and scoring system for evaluation of liver lesions in morbidly obese patients | Hepatology | 2012 | 657 |
| 39 | NASH limits anti-tumour surveillance in immunotherapy-treated HCC | Nature | 2021 | 649 |
| 40 | From Systemic T Cell Self-Reactivity to Organ-Specific Autoimmune Disease via Immunoglobulins | Immunity | 1999 | 646 |
| 41 | Drug-induced cholestasis | Journal of Hepatology | 1997 | 619 |
| 42 | Molecular basis for sunitinib efficacy and future clinical development | Nature Reviews Drug Discovery | 2007 | 616 |
| 43 | Efficacy and safety of selective internal radiotherapy with yttrium-90 resin microspheres compared with sorafenib in locally advanced and inoperable hepatocellular carcinoma (SARAH): an open-label randomised controlled phase 3 trial | Lancet Oncology, The | 2017 | 595 |
| 44 | Cause of portal or hepatic venous thrombosis in adults: The role of multiple concurrent factors | Hepatology | 2000 | 576 |
| 45 | Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped | Gastroenterology | 2012 | 558 |
| 46 | Tumor size predicts vascular invasion and histologic grade: Implications for selection of surgical treatment for hepatocellular carcinoma | Liver Transplantation | 2005 | 555 |
| 47 | ESPEN guidelines on chronic intestinal failure in adults | Clinical Nutrition | 2016 | 554 |
| 48 | Imaging techniques for assessment of inflammatory bowel disease: Joint ECCO and ESGAR evidence-based consensus guidelines | Journal of Crohn's and Colitis | 2013 | 541 |
| 49 | Genetic alterations associated with hepatocellular carcinomas define distinct pathways of hepatocarcinogenesis | Gastroenterology | 2001 | 539 |
| 50 | Predischarge B-type natriuretic peptide assay for identifying patients at high risk of re-admission after decompensated heart failure | Journal of the American College of Cardiology | 2004 | 534 |
