| # | Title | Journal | Year | Citations |
|---|
| 1 | A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 9,397 |
| 2 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 3 | Prediction of central nervous system embryonal tumour outcome based on gene expression | Nature | 2002 | 2,154 |
| 4 | Clinical Guidelines for the Use of Chronic Opioid Therapy in Chronic Noncancer Pain | Journal of Pain | 2009 | 1,960 |
| 5 | Phenomenology and classification of dystonia: A consensus update | Movement Disorders | 2013 | 1,754 |
| 6 | Effects of different doses in continuous veno-venous haemofiltration on outcomes of acute renal failure: a prospective randomised trial | Lancet, The | 2000 | 1,677 |
| 7 | Improving the Reporting Quality of Nonrandomized Evaluations of Behavioral and Public Health Interventions: The TREND Statement | American Journal of Public Health | 2004 | 1,636 |
| 8 | Global epidemiology of hepatitis B and hepatitis C in people who inject drugs: results of systematic reviews | Lancet, The | 2011 | 1,107 |
| 9 | Impact of Cancer‐Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition | Oncologist | 2000 | 1,048 |
| 10 | Global, regional, and national incidence and mortality for HIV, tuberculosis, and malaria during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 | Lancet, The | 2014 | 786 |
| 11 | Management of cancer pain | Lancet, The | 1999 | 719 |
| 12 | Screening for psychologic distress in ambulatory cancer patients | Cancer | 2005 | 696 |
| 13 | Nomenclature of the finer branches of the biliary tree: Canals, ductules, and ductular reactions in human livers | Hepatology | 2004 | 644 |
| 14 | Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease | Hepatology | 2008 | 630 |
| 15 | Tumor Hypoxia: Causative Factors, Compensatory Mechanisms, and Cellular Response | Oncologist | 2004 | 625 |
| 16 | Prediction of future cardiovascular outcomes by flow-mediated vasodilatation of brachial artery: a meta-analysis | International Journal of Cardiovascular Imaging | 2010 | 624 |
| 17 | Breakthrough pain: characteristics and impact in patients with cancer pain | Pain | 1999 | 602 |
| 18 | Carotid plaque, compared with carotid intima-media thickness, more accurately predicts coronary artery disease events: A meta-analysis | Atherosclerosis | 2012 | 601 |
| 19 | Psychometric properties of a Persian-language version of the Beck Depression Inventory - Second edition: BDI-II-PERSIAN | Depression and Anxiety | 2005 | 559 |
| 20 | Pain in the Emergency Department: Results of the Pain and Emergency Medicine Initiative (PEMI) Multicenter Study | Journal of Pain | 2007 | 550 |
| 21 | Multiple mechanisms of spiral wave breakup in a model of cardiac electrical activity | Chaos | 2002 | 542 |
| 22 | An international survey of cancer pain characteristics and syndromes | Pain | 1999 | 538 |
| 23 | Opioids and the treatment of chronic pain: Controversies, current status, and future directions. | Experimental and Clinical Psychopharmacology | 2008 | 528 |
| 24 | The Impact of Video Games on Training Surgeons in the 21st Century | Archives of Surgery | 2007 | 526 |
| 25 | Sex differences in the Toll-like receptor–mediated response of plasmacytoid dendritic cells to HIV-1 | Nature Medicine | 2009 | 523 |
| 26 | Genome-wide Analyses Identify KIF5A as a Novel ALS Gene | Neuron | 2018 | 517 |
| 27 | Visual illusion induced by sound | Cognitive Brain Research | 2002 | 515 |
| 28 | The mTORC1 Pathway Stimulates Glutamine Metabolism and Cell Proliferation by Repressing SIRT4 | Cell | 2013 | 505 |
| 29 | Body fluid volume determination via body composition spectroscopy in health and disease | Physiological Measurement | 2006 | 500 |
| 30 | Painful diabetic polyneuropathy: epidemiology, pain description, and quality of life | Diabetes Research and Clinical Practice | 2000 | 497 |
| 31 | Audio-computer interviewing to measure risk behaviour for HIV among injecting drug users: a quasi-randomised trial | Lancet, The | 1999 | 496 |
| 32 | Repairing alliance ruptures. | Psychotherapy | 2011 | 494 |
| 33 | American College of Critical Care Medicine Clinical Practice Parameters for Hemodynamic Support of Pediatric and Neonatal Septic Shock | Critical Care Medicine | 2017 | 475 |
| 34 | Efficacy of Obeticholic Acid in Patients With Primary Biliary Cirrhosis and Inadequate Response to Ursodeoxycholic Acid | Gastroenterology | 2015 | 470 |
| 35 | Morphology, Anatomic Distribution and Cancer Potential of Colonic Polyps | Annals of Surgery | 1979 | 467 |
| 36 | The DYT1 phenotype and guidelines for diagnostic testing | Neurology | 2000 | 467 |
| 37 | Mutations in the Na+/K+-ATPase α3 Gene ATP1A3 Are Associated with Rapid-Onset Dystonia Parkinsonism | Neuron | 2004 | 466 |
| 38 | Perfusion Assessment in Laparoscopic Left-Sided/Anterior Resection (PILLAR II): A Multi-Institutional Study | Journal of the American College of Surgeons | 2015 | 453 |
| 39 | The Gonadotropic Function of Insulin* | Endocrine Reviews | 1987 | 449 |
| 40 | A Randomized Trial of Postoperative Adjuvant Therapy in Patients with Completely Resected Stage II or IIIa Non–Small-Cell Lung Cancer | New England Journal of Medicine | 2000 | 448 |
| 41 | Nosocomial Outbreak Due to Enterococcus faecium Highly Resistant to Vancomycin, Penicillin, and Gentamicin | Clinical Infectious Diseases | 1993 | 441 |
| 42 | Relief of painful diabetic peripheral neuropathy with pregabalin: A randomized, placebo-controlled trial | Journal of Pain | 2005 | 438 |
| 43 | Clinical Practice Guideline: Improving Voice Outcomes after Thyroid Surgery | Otolaryngology - Head and Neck Surgery | 2013 | 435 |
| 44 | The Measurement of Symptoms in Children with Cancer | Journal of Pain and Symptom Management | 2000 | 424 |
| 45 | Atrial fibrillation and obesity—results of a meta-analysis | American Heart Journal | 2008 | 417 |
| 46 | Treatment of cancer pain | Lancet, The | 2011 | 415 |
| 47 | The Differential Effects of Face-to-Face and Computer Interview Modes | American Journal of Public Health | 2002 | 385 |
| 48 | Mutations in the THAP1 gene are responsible for DYT6 primary torsion dystonia | Nature Genetics | 2009 | 384 |
| 49 | HIV incidence among injecting drug users in New York City syringe-exchange programmes | Lancet, The | 1996 | 383 |
| 50 | Endovenous Laser | Dermatologic Surgery | 2001 | 371 |
