Whole genomes redefine the mutational landscape of pancreatic cancer | Nature | 2015 | 1.6K |
International Consensus Guidance Statement on the Management and Treatment of IgG4-Related Disease | Arthritis and Rheumatology | 2015 | 546 |
Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction | Nature | 2015 | 463 |
Neutrophils promote Alzheimer's disease-like pathology and cognitive decline via LFA-1 integrin | Nature Medicine | 2015 | 354 |
Differential Activity of Nivolumab, Pembrolizumab and MPDL3280A according to the Tumor Expression of Programmed Death-Ligand-1 (PD-L1): Sensitivity Analysis of Trials in Melanoma, Lung and Genitourinary Cancers | PLoS ONE | 2015 | 339 |
Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera | Nature Communications | 2015 | 300 |
Understanding pathologic variants of renal cell carcinoma: distilling therapeutic opportunities from biologic complexity | European Urology | 2015 | 292 |
Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in patients with moderate-to-severe plaque psoriasis over 52 weeks: a phase III, randomized controlled trial (ESTEEM 2) | British Journal of Dermatology | 2015 | 288 |
Convergent mutations and kinase fusions lead to oncogenic STAT3 activation in anaplastic large cell lymphoma | Cancer Cell | 2015 | 283 |
Epidemiological modifiers of non-alcoholic fatty liver disease: Focus on high-risk groups | Digestive and Liver Disease | 2015 | 279 |
European S3-Guidelines on the systemic treatment of psoriasis vulgaris--Update 2015--Short version--EDF in cooperation with EADV and IPC | Journal of the European Academy of Dermatology and Venereology | 2015 | 271 |
Pharmacotherapy for post-traumatic stress disorder: systematic review and meta-analysis | British Journal of Psychiatry | 2015 | 223 |
Effect of Vitamin D Supplementation on Blood Pressure: A Systematic Review and Meta-analysis Incorporating Individual Patient Data | JAMA Internal Medicine | 2015 | 219 |
Adult lung function and long-term air pollution exposure. ESCAPE: a multicentre cohort study and meta-analysis | European Respiratory Journal | 2015 | 218 |
Decreased epigenetic age of PBMCs from Italian semi-supercentenarians and their offspring | Aging | 2015 | 211 |
Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel | Nature Communications | 2015 | 186 |
Prevalence and Risk Factors of Violence by Psychiatric Acute Inpatients: A Systematic Review and Meta-Analysis | PLoS ONE | 2015 | 185 |
Dose equivalents of antidepressants: Evidence-based recommendations from randomized controlled trials | Journal of Affective Disorders | 2015 | 178 |
Boosting the sensitivity of Nd(3+)-based luminescent nanothermometers | Nanoscale | 2015 | 172 |
Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia | Blood | 2015 | 167 |
The phenylpropanoid pathway is controlled at different branches by a set of R2R3-MYB C2 repressors in grapevine | Plant Physiology | 2015 | 167 |
Fiscal and monetary policies in complex evolving economies | Journal of Economic Dynamics and Control | 2015 | 155 |
Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid | MBio | 2015 | 149 |
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility | Nature Communications | 2015 | 147 |
Ambient air pollution and adult asthma incidence in six European cohorts (ESCAPE) | Environmental Health Perspectives | 2015 | 142 |