| # | Title | Journal | Year | Citations |
|---|
| 1 | A Comparison of Balloon-Expandable-Stent Implantation with Balloon Angioplasty in Patients with Coronary Artery Disease | New England Journal of Medicine | 1994 | 4,235 |
| 2 | STARD 2015: an updated list of essential items for reporting diagnostic accuracy studies | BMJ, The | 2015 | 1,914 |
| 3 | Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis | Lancet, The | 2007 | 1,329 |
| 4 | Routine Use of the Confusion Assessment Method for the Intensive Care Unit | American Journal of Respiratory and Critical Care Medicine | 2011 | 1,318 |
| 5 | European Hernia Society guidelines on the treatment of inguinal hernia in adult patients | Hernia: the Journal of Hernias and Abdominal Wall Surgery | 2009 | 1,215 |
| 6 | Continuous renal replacement therapy: A worldwide practice survey | Intensive Care Medicine | 2007 | 1,020 |
| 7 | Nitroglycerin in septic shock after intravascular volume resuscitation | Lancet, The | 2002 | 1,014 |
| 8 | Classification of primary and incisional abdominal wall hernias | Hernia: the Journal of Hernias and Abdominal Wall Surgery | 2009 | 915 |
| 9 | A Randomized Comparison of Percutaneous Transluminal Coronary Angioplasty by the Radial, Brachial and Femoral Approaches: The Access Study | Journal of the American College of Cardiology | 1997 | 847 |
| 10 | Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy | Lancet, The | 1999 | 843 |
| 11 | Effectiveness of positron emission tomography in the preoperative assessment of patients with suspected non-small-cell lung cancer: the PLUS multicentre randomised trial | Lancet, The | 2002 | 823 |
| 12 | Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers | Nature Medicine | 2020 | 736 |
| 13 | Laparoscopy in Combination with Fast Track Multimodal Management is the Best Perioperative Strategy in Patients Undergoing Colonic Surgery | Annals of Surgery | 2011 | 674 |
| 14 | Preoperative Chemoradiotherapy Versus Immediate Surgery for Resectable and Borderline Resectable Pancreatic Cancer: Results of the Dutch Randomized Phase III PREOPANC Trial | Journal of Clinical Oncology | 2020 | 665 |
| 15 | Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia after 36 weeks' gestation (HYPITAT): a multicentre, open-label randomised controlled trial | Lancet, The | 2009 | 648 |
| 16 | Future challenges for clinical care of an ageing population infected with HIV: a modelling study | Lancet Infectious Diseases, The | 2015 | 634 |
| 17 | Diastolic Stiffness of the Failing Diabetic Heart | Circulation | 2008 | 621 |
| 18 | Randomised comparison of implantation of heparin-coated stents with balloon angioplasty in selected patients with coronary artery disease (Benestent II) | Lancet, The | 1998 | 613 |
| 19 | Ticagrelor plus aspirin for 1 month, followed by ticagrelor monotherapy for 23 months vs aspirin plus clopidogrel or ticagrelor for 12 months, followed by aspirin monotherapy for 12 months after implantation of a drug-eluting stent: a multicentre, open-label, randomised superiority trial | Lancet, The | 2018 | 555 |
| 20 | A bioresorbable everolimus-eluting scaffold versus a metallic everolimus-eluting stent for ischaemic heart disease caused by de-novo native coronary artery lesions (ABSORB II): an interim 1-year analysis of clinical and procedural secondary outcomes from a randomised controlled trial | Lancet, The | 2015 | 514 |
| 21 | Intensive care information system reduces documentation time of the nurses after cardiothoracic surgery | Intensive Care Medicine | 2003 | 510 |
| 22 | Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial | Lancet, The | 2018 | 504 |
| 23 | STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies | Radiology | 2015 | 474 |
| 24 | STARD 2015: An Updated List of Essential Items for Reporting Diagnostic Accuracy Studies | Clinical Chemistry | 2015 | 449 |
| 25 | EORTC Nomograms and Risk Groups for Predicting Recurrence, Progression, and Disease-specific and Overall Survival in Non–Muscle-invasive Stage Ta–T1 Urothelial Bladder Cancer Patients Treated with 1–3 Years of Maintenance Bacillus Calmette-Guérin | European Urology | 2016 | 445 |
| 26 | Acute Upper Gi Bleeding: Did Anything Change? | American Journal of Gastroenterology | 2003 | 434 |
| 27 | Standardization of terminology of pelvic floor muscle function and dysfunction: Report from the pelvic floor clinical assessment group of the International Continence Society | Neurourology and Urodynamics | 2005 | 433 |
| 28 | Healthcare costs of inflammatory bowel disease have shifted from hospitalisation and surgery towards anti-TNFα therapy: results from the COIN study | Gut | 2014 | 430 |
| 29 | Intensive oral antiplatelet therapy for reduction of ischaemic events including stent thrombosis in patients with acute coronary syndromes treated with percutaneous coronary intervention and stenting in the TRITON-TIMI 38 trial: a subanalysis of a randomised trial | Lancet, The | 2008 | 420 |
| 30 | Frequency-dependent functional connectivity within resting-state networks: An atlas-based MEG beamformer solution | NeuroImage | 2012 | 408 |
| 31 | Minimally Invasive Versus Open Distal Pancreatectomy (LEOPARD) | Annals of Surgery | 2019 | 401 |
| 32 | Paclitaxel-Eluting versus Uncoated Stents in Primary Percutaneous Coronary Intervention | New England Journal of Medicine | 2006 | 399 |
| 33 | Laparoscopic versus open pancreatoduodenectomy for pancreatic or periampullary tumours (LEOPARD-2): a multicentre, patient-blinded, randomised controlled phase 2/3 trial | The Lancet Gastroenterology and Hepatology | 2019 | 393 |
| 34 | Mean wall thickness of trabecular bone packets in the human iliac crest: Changes with age | Calcified Tissue Research | 1978 | 384 |
| 35 | Final Results of an EORTC-GU Cancers Group Randomized Study of Maintenance Bacillus Calmette-Guérin in Intermediate- and High-risk Ta, T1 Papillary Carcinoma of the Urinary Bladder: One-third Dose Versus Full Dose and 1 Year Versus 3 Years of Maintenance | European Urology | 2013 | 382 |
| 36 | Induction versus expectant monitoring for intrauterine growth restriction at term: randomised equivalence trial (DIGITAT) | BMJ: British Medical Journal | 2010 | 375 |
| 37 | Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial | European Urology | 2019 | 375 |
| 38 | An international field study of the EORTC QLQ-PR25: A questionnaire for assessing the health-related quality of life of patients with prostate cancer | European Journal of Cancer | 2008 | 370 |
| 39 | Simplified diagnostic management of suspected pulmonary embolism (the YEARS study): a prospective, multicentre, cohort study | Lancet, The | 2017 | 357 |
| 40 | Percutaneous transradial artery approach for coronary stent implantation | Catheterization and Cardiovascular Diagnosis | 1993 | 356 |
| 41 | Aprotinin protects platelets against the initial effect of cardiopulmonary bypass | Journal of Thoracic and Cardiovascular Surgery | 1990 | 355 |
| 42 | Citrate anticoagulation for continuous venovenous hemofiltration* | Critical Care Medicine | 2009 | 349 |
| 43 | Life expectancy of recently diagnosed asymptomatic HIV-infected patients approaches that of uninfected individuals | Aids | 2010 | 349 |
| 44 | Loss of Infliximab Into Feces Is Associated With Lack of Response to Therapy in Patients With Severe Ulcerative Colitis | Gastroenterology | 2015 | 342 |
| 45 | Automated Detection and Differentiation of Drusen, Exudates, and Cotton-Wool Spots in Digital Color Fundus Photographs for Diabetic Retinopathy Diagnosis | | 2007 | 328 |
| 46 | EUROSCAN, a Randomized Trial of Vitamin A and N-Acetylcysteine in Patients With Head and Neck Cancer or Lung Cancer | Journal of the National Cancer Institute | 2000 | 322 |
| 47 | Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients | Critical Care | 2008 | 318 |
| 48 | Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5 years | British Journal of Surgery | 2017 | 304 |
| 49 | Endovascular Repair Versus Open Repair of Ruptured Abdominal Aortic Aneurysms | Annals of Surgery | 2013 | 302 |
| 50 | Plasma glutamine depletion and patient outcome in acute ICU admissions | Intensive Care Medicine | 2001 | 301 |
