| # | Title | Journal | Year | Citations |
|---|
| 1 | Endoscopic or surgical step-up approach for infected necrotising pancreatitis: a multicentre randomised trial | Lancet, The | 2018 | 504 |
| 2 | Adrenal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up | Annals of Oncology | 2012 | 263 |
| 3 | Prevention of incisional hernia with prophylactic onlay and sublay mesh reinforcement versus primary suture only in midline laparotomies (PRIMA): 2-year follow-up of a multicentre, double-blind, randomised controlled trial | Lancet, The | 2017 | 221 |
| 4 | Prognostic factors in stage III–IV adrenocortical carcinomas (ACC): an European Network for the Study of Adrenal Tumor (ENSAT) study | Annals of Oncology | 2015 | 196 |
| 5 | GRIN2Bencephalopathy: novel findings on phenotype, variant clustering, functional consequences and treatment aspects | Journal of Medical Genetics | 2017 | 190 |
| 6 | Identification of Patients With Variants in TPMT and Dose Reduction Reduces Hematologic Events During Thiopurine Treatment of Inflammatory Bowel Disease | Gastroenterology | 2015 | 169 |
| 7 | Network localization of cervical dystonia based on causal brain lesions | Brain | 2019 | 160 |
| 8 | Recommendations for antibacterial therapy in adults with COVID-19 – an evidence based guideline | Clinical Microbiology and Infection | 2021 | 147 |
| 9 | Appendectomy versus antibiotic treatment for acute appendicitis | The Cochrane Library | 2011 | 128 |
| 10 | Exhaled nitric oxide and biomarkers in exhaled breath condensate indicate the presence, severity and control of childhood asthma | Clinical and Experimental Allergy | 2007 | 124 |
| 11 | Is extensive screening for cancer in idiopathic venous thromboembolism warranted? | Journal of Thrombosis and Haemostasis | 2011 | 117 |
| 12 | Prion protein amyloidosis with divergent phenotype associated with two novel nonsense mutations in PRNP | Acta Neuropathologica | 2010 | 116 |
| 13 | Functional convergence of histone methyltransferases EHMT1 and KMT2C involved in intellectual disability and autism spectrum disorder | PLoS Genetics | 2017 | 116 |
| 14 | Uncommon breast tumors in perspective: Incidence, treatment and survival in the Netherlands | International Journal of Cancer | 2007 | 114 |
| 15 | Efficacy and Costs of Nutritional Rehabilitation in Muscle-Wasted Patients With Chronic Obstructive Pulmonary Disease in a Community-Based Setting: A Prespecified Subgroup Analysis of the INTERCOM Trial | Journal of the American Medical Directors Association | 2010 | 113 |
| 16 | Cardiac rehabilitation and survival in a large representative community cohort of Dutch patients | European Heart Journal | 2015 | 110 |
| 17 | Adult-onset autoinflammation caused by somatic mutations in UBA1: A Dutch case series of patients with VEXAS | Journal of Allergy and Clinical Immunology | 2022 | 105 |
| 18 | Lysine restricted diet for pyridoxine-dependent epilepsy: First evidence and future trials | Molecular Genetics and Metabolism | 2012 | 97 |
| 19 | Adjuvant Therapy in Patients With Adrenocortical Carcinoma: A Position of an International Panel | Journal of Clinical Oncology | 2010 | 95 |
| 20 | Exercise Testing and Training in a Cancer Rehabilitation Program: The Advantage of the Steep Ramp Test | Archives of Physical Medicine and Rehabilitation | 2007 | 87 |
| 21 | Roux-en-Y Gastric Bypass Surgery, but Not Calorie Restriction, Reduces Plasma Branched-Chain Amino Acids in Obese Women Independent of Weight Loss or the Presence of Type 2 Diabetes | Diabetes Care | 2014 | 80 |
| 22 | The ARID1B spectrum in 143 patients: from nonsyndromic intellectual disability to Coffin–Siris syndrome | Genetics in Medicine | 2019 | 80 |
| 23 | Parasitic myoma after laparoscopic morcellation: a systematic review of the literature | BJOG: an International Journal of Obstetrics and Gynaecology | 2016 | 79 |
| 24 | Mesenchymal Stem Cells Induce T-Cell Tolerance and Protect the Preterm Brain after Global Hypoxia-Ischemia | PLoS ONE | 2013 | 78 |
| 25 | High-intensity strength training improves quality of life in cancer survivors | Acta Oncológica | 2007 | 76 |
| 26 | Cerebral inflammation and mobilization of the peripheral immune system following global hypoxia-ischemia in preterm sheep | Journal of Neuroinflammation | 2013 | 74 |
| 27 | Sentinel node micrometastases in breast cancer do not affect prognosis: a population-based study | Breast Cancer Research and Treatment | 2011 | 72 |
| 28 | Are breast conservation and mastectomy equally effective in the treatment of young women with early breast cancer? Long-term results of a population-based cohort of 1,451 patients aged ≤40 years | Breast Cancer Research and Treatment | 2011 | 72 |
| 29 | Randomized clinical trial of trigger point infiltration with lidocaine to diagnose anterior cutaneous nerve entrapment syndrome | British Journal of Surgery | 2012 | 72 |
| 30 | Calorie Restriction is a Major Determinant of the Short‐Term Metabolic Effects of Gastric Bypass Surgery in Obese Type 2 Diabetic Patients | Clinical Endocrinology | 2014 | 71 |
| 31 | Evaluating postherniorrhaphy groin pain: Visual Analogue or Verbal Rating Scale? | Hernia: the Journal of Hernias and Abdominal Wall Surgery | 2008 | 70 |
| 32 | Exercise training for patients with type 2 diabetes and cardiovascular disease: What to pursue and how to do it. A Position Paper of the European Association of Preventive Cardiology (EAPC) | European Journal of Preventive Cardiology | 2019 | 68 |
| 33 | Introduction of Hypothermia for Neonates with Perinatal Asphyxia in the Netherlands and Flanders | Neonatology | 2013 | 65 |
| 34 | Body mass index predicts discontinuation due to ineffectiveness and female sex predicts discontinuation due to side-effects in patients with psoriasis treated with adalimumab, etanercept or ustekinumab in daily practice: a prospective, comparative, long-t | British Journal of Dermatology | 2016 | 65 |
| 35 | Simulation‐based team training for multi‐professional obstetric care teams to improve patient outcome: a multicentre, cluster randomised controlled trial | BJOG: an International Journal of Obstetrics and Gynaecology | 2017 | 65 |
| 36 | Short-Chain Acyl-CoA Dehydrogenase Deficiency: Studies in a Large Family Adding to the Complexity of the Disorder | Pediatrics | 2003 | 64 |
| 37 | Differences in Response and Surgical Management with Neoadjuvant Chemotherapy in Invasive Lobular Versus Ductal Breast Cancer | Annals of Surgical Oncology | 2016 | 63 |
| 38 | Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers | European Heart Journal | 2016 | 63 |
| 39 | Development and evaluation of a follow up assessment of preterm infants at 5 years of age | Archives of Disease in Childhood | 2003 | 62 |
| 40 | Beat-to-beat detection of fetal heart rate: Doppler ultrasound cardiotocography compared to direct ECG cardiotocography in time and frequency domain | Physiological Measurement | 2004 | 60 |
| 41 | PURA syndrome: clinical delineation and genotype-phenotype study in 32 individuals with review of published literature | Journal of Medical Genetics | 2018 | 59 |
| 42 | Necrotizing Enterocolitis, Gut Microbiota, and Brain Development: Role of the Brain-Gut Axis | Neonatology | 2019 | 59 |
| 43 | The effect of 3% and 6% hypertonic saline in viral bronchiolitis: a randomised controlled trial | European Respiratory Journal | 2014 | 56 |
| 44 | Predicting Neonatal Sepsis Using Features of Heart Rate Variability, Respiratory Characteristics, and ECG-Derived Estimates of Infant Motion | IEEE Journal of Biomedical and Health Informatics | 2020 | 56 |
| 45 | The genomic landscape of 85 advanced neuroendocrine neoplasms reveals subtype-heterogeneity and potential therapeutic targets | Nature Communications | 2021 | 55 |
| 46 | Quality of life in children with undiagnosed and diagnosed asthma | European Journal of Pediatrics | 2007 | 54 |
| 47 | The FAST-EU trial: 12-month clinical outcomes of women after intrauterine sonography-guided transcervical radiofrequency ablation of uterine fibroids | Gynecological Surgery | 2016 | 54 |
| 48 | Lymphatic mapping and sentinel node harvesting in patients with recurrent breast cancer | European Journal of Surgical Oncology | 2006 | 53 |
| 49 | Metroplasty versus expectant management for women with recurrent miscarriage and a septate uterus | | 2011 | 52 |
| 50 | Early Assessment of Thiopurine Metabolites Identifies Patients at Risk of Thiopurine-induced Leukopenia in Inflammatory Bowel Disease | Journal of Crohn's and Colitis | 2017 | 52 |
