| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Advanced capabilities for materials modelling with Quantum ESPRESSO | Journal of Physics Condensed Matter | 2017 | 4,303 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 4 | Set invariance in control | Automatica | 1999 | 1,857 |
| 5 | Characterization of polyploid wheat genomic diversity using a high‐density 90 000 single nucleotide polymorphism array | Plant Biotechnology Journal | 2014 | 1,828 |
| 6 | Renal cell carcinoma | Nature Reviews Disease Primers | 2017 | 1,727 |
| 7 | Inflammatory Cytokine Concentrations Are Acutely Increased by Hyperglycemia in Humans | Circulation | 2002 | 1,717 |
| 8 | Revision and Update of the Consensus Definitions of Invasive Fungal Disease From the European Organization for Research and Treatment of Cancer and the Mycoses Study Group Education and Research Consortium | Clinical Infectious Diseases | 2020 | 1,429 |
| 9 | Modelling the COVID-19 epidemic and implementation of population-wide interventions in Italy | Nature Medicine | 2020 | 1,373 |
| 10 | A chromosome conformation capture ordered sequence of the barley genome | Nature | 2017 | 1,365 |
| 11 | Is Oxidative Stress the Pathogenic Mechanism Underlying Insulin Resistance, Diabetes, and Cardiovascular Disease? The Common Soil Hypothesis Revisited | Arteriosclerosis, Thrombosis, and Vascular Biology | 2004 | 1,151 |
| 12 | Reproducibility in density functional theory calculations of solids | Science | 2016 | 1,113 |
| 13 | The high-quality draft genome of peach (Prunus persica) identifies unique patterns of genetic diversity, domestication and genome evolution | Nature Genetics | 2013 | 1,031 |
| 14 | Effect of epidural stimulation of the lumbosacral spinal cord on voluntary movement, standing, and assisted stepping after motor complete paraplegia: a case study | Lancet, The | 2011 | 964 |
| 15 | Postprandial Hyperglycemia and Diabetes Complications: Is It Time to Treat? | Diabetes | 2005 | 874 |
| 16 | Cathelicidins, multifunctional peptides of the innate immunity | Journal of Leukocyte Biology | 2004 | 858 |
| 17 | Dimers of mitochondrial ATP synthase form the permeability transition pore | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 822 |
| 18 | Tocilizumab in patients with severe COVID-19: a retrospective cohort study | Lancet Rheumatology, The | 2020 | 772 |
| 19 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 20 | Treatment of HER2-positive breast cancer: current status and future perspectives | Nature Reviews Clinical Oncology | 2012 | 735 |
| 21 | Intermittent High Glucose Enhances Apoptosis Related to Oxidative Stress in Human Umbilical Vein Endothelial Cells: The Role of Protein Kinase C and NAD(P)H-Oxidase Activation | Diabetes | 2003 | 710 |
| 22 | [5] Diversity of glutathione peroxidases | Methods in Enzymology | 1995 | 704 |
| 23 | Autologous Transplantation and Maintenance Therapy in Multiple Myeloma | New England Journal of Medicine | 2014 | 683 |
| 24 | Neural Circuits Involved in the Recognition of Actions Performed by Nonconspecifics: An fMRI Study | Journal of Cognitive Neuroscience | 2004 | 663 |
| 25 | Microbial interactions in the rhizosphere: beneficial influences of plant growth-promoting rhizobacteria on nutrient acquisition process. A review | Biology and Fertility of Soils | 2015 | 658 |
| 26 | Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study) | Diabetes Care | 2010 | 656 |
| 27 | New Insights on Oxidative Stress and Diabetic Complications May Lead to a "Causal" Antioxidant Therapy | Diabetes Care | 2003 | 644 |
| 28 | Design concepts for the Cherenkov Telescope Array CTA: an advanced facility for ground-based high-energy gamma-ray astronomy | Experimental Astronomy | 2011 | 640 |
| 29 | Evidence for an Independent and Cumulative Effect of Postprandial Hypertriglyceridemia and Hyperglycemia on Endothelial Dysfunction and Oxidative Stress Generation | Circulation | 2002 | 616 |
| 30 | Cardiac output monitoring: aortic transpulmonary thermodilution and pulse contour analysis agree with standard thermodilution methods in patients undergoing lung transplantation | Canadian Journal of Anaesthesia | 2003 | 591 |
| 31 | High-dose cytarabine plus high-dose methotrexate versus high-dose methotrexate alone in patients with primary CNS lymphoma: a randomised phase 2 trial | Lancet, The | 2009 | 588 |
| 32 | Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure | Proceedings of the National Academy of Sciences of the United States of America | 2005 | 587 |
| 33 | Structural basis of end-stage failure in ischemic cardiomyopathy in humans. | Circulation | 1994 | 551 |
| 34 | A Simple Sequence Repeat-Based Linkage Map of Barley | Genetics | 2000 | 548 |
| 35 | Regeneration of the entire human epidermis using transgenic stem cells | Nature | 2017 | 544 |
| 36 | Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 536 |
| 37 | Energy Cost and Metabolic Power in Elite Soccer | Medicine and Science in Sports and Exercise | 2010 | 532 |
| 38 | Neonicotinoid clothianidin adversely affects insect immunity and promotes replication of a viral pathogen in honey bees | Proceedings of the National Academy of Sciences of the United States of America | 2013 | 531 |
| 39 | Plant Flavonoids—Biosynthesis, Transport and Involvement in Stress Responses | International Journal of Molecular Sciences | 2013 | 528 |
| 40 | Water deficits accelerate ripening and induce changes in gene expression regulating flavonoid biosynthesis in grape berries | Planta | 2007 | 527 |
| 41 | Dissecting iron deficiency‐induced proton extrusion in Arabidopsis roots | New Phytologist | 2009 | 510 |
| 42 | Short term soil priming effects and the mineralisation of biochar following its incorporation to soils of different pH | Soil Biology and Biochemistry | 2011 | 510 |
| 43 | Impedance measurements to study the antimicrobial activity of essential oils from Lamiaceae and Compositae | International Journal of Food Microbiology | 2001 | 502 |
| 44 | On the shoulders of giants: undertaking a structured literature review in accounting | Accounting, Auditing and Accountability Journal | 2016 | 482 |
| 45 | A Comparison of Allografting with Autografting for Newly Diagnosed Myeloma | New England Journal of Medicine | 2007 | 479 |
| 46 | Transcriptional regulation of anthocyanin biosynthesis in ripening fruits of grapevine under seasonal water deficit | Plant, Cell and Environment | 2007 | 476 |
| 47 | Cardiovascular Outcomes in Patients With Primary Aldosteronism After Treatment | Archives of Internal Medicine | 2008 | 476 |
| 48 | Contribution of ABL Kinase Domain Mutations to Imatinib Resistance in Different Subsets of Philadelphia-Positive Patients: By the GIMEMA Working Party on Chronic Myeloid Leukemia | Clinical Cancer Research | 2006 | 475 |
| 49 | Efficacy and safety of rituximab in type II mixed cryoglobulinemia | Blood | 2003 | 471 |
| 50 | The genome of the seagrass Zostera marina reveals angiosperm adaptation to the sea | Nature | 2016 | 460 |
