| # | Title | Journal | Year | Citations |
|---|
| 1 | Chronic inflammation in the etiology of disease across the life span | Nature Medicine | 2019 | 2,195 |
| 2 | Adult hippocampal neurogenesis is abundant in neurologically healthy subjects and drops sharply in patients with Alzheimer’s disease | Nature Medicine | 2019 | 1,070 |
| 3 | Exercise benefits in cardiovascular disease: beyond attenuation of traditional risk factors | Nature Reviews Cardiology | 2018 | 449 |
| 4 | Bacteremic Pneumonia Due to Staphylococcus aureus: A Comparison of Disease Caused by Methicillin-Resistant and Methicillin-Susceptible Organisms | Clinical Infectious Diseases | 1999 | 383 |
| 5 | Healthspan and lifespan extension by fecal microbiota transplantation into progeroid mice | Nature Medicine | 2019 | 352 |
| 6 | Integrated QFD-MCDM framework for green supplier selection | Journal of Cleaner Production | 2017 | 321 |
| 7 | Skeletal Muscle Regulates Metabolism via Interorgan Crosstalk: Roles in Health and Disease | Journal of the American Medical Directors Association | 2016 | 317 |
| 8 | Romosozumab (sclerostin monoclonal antibody) versus teriparatide in postmenopausal women with osteoporosis transitioning from oral bisphosphonate therapy: a randomised, open-label, phase 3 trial | Lancet, The | 2017 | 313 |
| 9 | Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy | Nature Medicine | 2013 | 296 |
| 10 | Effect of Exercise Intervention on Functional Decline in Very Elderly Patients During Acute Hospitalization | JAMA Internal Medicine | 2019 | 288 |
| 11 | An International Definition for “Nursing Home” | Journal of the American Medical Directors Association | 2015 | 286 |
| 12 | Exercise Attenuates the Major Hallmarks of Aging | Rejuvenation Research | 2015 | 275 |
| 13 | Actigraph GT3X: Validation and Determination of Physical Activity Intensity Cut Points | International Journal of Sports Medicine | 2013 | 269 |
| 14 | Exerkines in health, resilience and disease | Nature Reviews Endocrinology | 2022 | 268 |
| 15 | Metabolic Impacts of Confinement during the COVID-19 Pandemic Due to Modified Diet and Physical Activity Habits | Nutrients | 2020 | 263 |
| 16 | Saliva Composition and Exercise | Sports Medicine | 1998 | 259 |
| 17 | The architecture of the left lateral atrial wall: a particular anatomic region with implications for ablation of atrial fibrillation | European Heart Journal | 2008 | 249 |
| 18 | Root Anatomy and Canal Configuration of the Permanent Mandibular First Molar: A Systematic Review | Journal of Endodontics | 2010 | 245 |
| 19 | Heart rate and performance parameters in elite cyclists: a longitudinal study. | Medicine and Science in Sports and Exercise | 2000 | 222 |
| 20 | INTUITIONISTIC FUZZY EDAS METHOD: AN APPLICATION TO SOLID WASTE DISPOSAL SITE SELECTION | Journal of Environmental Engineering and Landscape Management | 2017 | 220 |
| 21 | Hypoglycemia in Older People - A Less Well Recognized Risk Factor for Frailty | Journal of Environmental Engineering and Landscape Management | 2015 | 213 |
| 22 | Frailty in the clinical scenario | Lancet, The | 2015 | 206 |
| 23 | A survey of data mining and knowledge discovery process models and methodologies | Knowledge Engineering Review | 2010 | 201 |
| 24 | A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease | Frontiers in Immunology | 2020 | 201 |
| 25 | McArdle disease: what do neurologists need to know? | Nature Clinical Practice Neurology | 2008 | 195 |
| 26 | Corporate social performance and its relation with corporate financial performance: International evidence in the banking industry | Journal of Cleaner Production | 2017 | 193 |
| 27 | Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry | European Heart Journal | 2019 | 189 |
| 28 | Oral vesiculobullous lesions associated with SARS‐CoV‐2 infection | Oral Diseases | 2021 | 189 |
| 29 | Keratoconus: An updated review | Contact Lens and Anterior Eye | 2022 | 176 |
| 30 | A Comprehensive Model for the Monoceros Tidal Stream | Astrophysical Journal | 2005 | 173 |
| 31 | Efficacy of Different Irrigation and Activation Systems on the Penetration of Sodium Hypochlorite into Simulated Lateral Canals and up to Working Length: An In Vitro Study | Journal of Endodontics | 2010 | 173 |
| 32 | Physiological characteristics of the best Eritrean runners—exceptional running economy | Applied Physiology, Nutrition and Metabolism | 2006 | 166 |
| 33 | Long-Term Benefit of Early Pre-Reperfusion Metoprolol Administration in Patients With Acute Myocardial Infarction | Journal of the American College of Cardiology | 2014 | 162 |
| 34 | Frailty and sarcopenia - newly emerging and high impact complications of diabetes | Journal of Diabetes and Its Complications | 2017 | 160 |
| 35 | Gut Microbiota Modification: Another Piece in the Puzzle of the Benefits of Physical Exercise in Health? | Frontiers in Physiology | 2016 | 156 |
| 36 | Effects of an Intrahospital Exercise Program Intervention for Children with Leukemia | Medicine and Science in Sports and Exercise | 2007 | 153 |
| 37 | Exercise benefits on Alzheimer’s disease: State-of-the-science | Ageing Research Reviews | 2020 | 153 |
| 38 | Exercise Training is Beneficial for Alzheimer's Patients | International Journal of Sports Medicine | 2008 | 151 |
| 39 | Effect of EDTA, Sonic, and Ultrasonic Activation on the Penetration of Sodium Hypochlorite into Simulated Lateral Canals: An In Vitro Study | Journal of Endodontics | 2009 | 149 |
| 40 | Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness | Nature Communications | 2017 | 149 |
| 41 | Preferred pedalling cadence in professional cycling | Medicine and Science in Sports and Exercise | 2001 | 145 |
| 42 | Technical variability of the GT3X accelerometer | Medical Engineering and Physics | 2012 | 145 |
| 43 | Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention | Journal of the American College of Cardiology | 2016 | 144 |
| 44 | An application of an integrated ANP–QFD framework for sustainable supplier selection | International Journal of Logistics Research and Applications | 2017 | 143 |
| 45 | Efficacy and Safety of IDegLira Versus Basal-Bolus Insulin Therapy in Patients With Type 2 Diabetes Uncontrolled on Metformin and Basal Insulin: The DUAL VII Randomized Clinical Trial | Diabetes Care | 2018 | 143 |
| 46 | Content based SMS spam filtering | Diabetes Care | 2006 | 141 |
| 47 | ‘Adipaging’: ageing and obesity share biological hallmarks related to a dysfunctional adipose tissue | Journal of Physiology | 2016 | 136 |
| 48 | Impact of neurodegenerative diseases on human adult hippocampal neurogenesis | Science | 2021 | 136 |
| 49 | Lokomat Robotic-Assisted Versus Overground Training Within 3 to 6 Months of Incomplete Spinal Cord Lesion | Neurorehabilitation and Neural Repair | 2012 | 131 |
| 50 | Exercise during pregnancy and gestational diabetes-related adverse effects: a randomised controlled trial | British Journal of Sports Medicine | 2013 | 131 |
