| # | Title | Journal | Year | Citations |
|---|
| 1 | Ferric Carboxymaltose in Patients with Heart Failure and Iron Deficiency | New England Journal of Medicine | 2009 | 1,633 |
| 2 | Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation | New England Journal of Medicine | 2019 | 833 |
| 3 | Regional Variation in Patients and Outcomes in the Treatment of Preserved Cardiac Function Heart Failure With an Aldosterone Antagonist (TOPCAT) Trial | Circulation | 2015 | 758 |
| 4 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 5 | Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA | Developmental Cell | 2005 | 609 |
| 6 | VDJtools: Unifying Post-analysis of T Cell Receptor Repertoires | PLoS Computational Biology | 2015 | 528 |
| 7 | Local fitness landscape of the green fluorescent protein | Nature | 2016 | 438 |
| 8 | A New Variant of Charcot-Marie-Tooth Disease Type 2 Is Probably the Result of a Mutation in the Neurofilament-Light Gene | American Journal of Human Genetics | 2000 | 411 |
| 9 | VDJdb: a curated database of T-cell receptor sequences with known antigen specificity | Nucleic Acids Research | 2018 | 391 |
| 10 | B cells, plasma cells and antibody repertoires in the tumour microenvironment | Nature Reviews Immunology | 2020 | 363 |
| 11 | Early onset multiple sclerosis | Neurology | 2002 | 359 |
| 12 | The Jervell and Lange-Nielsen Syndrome | Circulation | 2006 | 331 |
| 13 | Action Plan for Stroke in Europe 2018–2030 | European Stroke Journal | 2018 | 311 |
| 14 | Pathway Based Analysis of Mutation Data Is Efficient for Scoring Target Cancer Drugs | Frontiers in Pharmacology | 2019 | 303 |
| 15 | Genome-wide association study reveals two new risk loci for bipolar disorder | Nature Communications | 2014 | 294 |
| 16 | Atacicept in multiple sclerosis (ATAMS): a randomised, placebo-controlled, double-blind, phase 2 trial | Lancet Neurology, The | 2014 | 271 |
| 17 | The management of intra-abdominal infections from a global perspective: 2017 WSES guidelines for management of intra-abdominal infections | World Journal of Emergency Surgery | 2017 | 271 |
| 18 | Effect of laquinimod on MRI-monitored disease activity in patients with relapsing-remitting multiple sclerosis: a multicentre, randomised, double-blind, placebo-controlled phase IIb study | Lancet, The | 2008 | 265 |
| 19 | Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: The randomized PILLAR study | Hepatology | 2013 | 255 |
| 20 | Pomalidomide, bortezomib, and dexamethasone for patients with relapsed or refractory multiple myeloma previously treated with lenalidomide (OPTIMISMM): a randomised, open-label, phase 3 trial | Lancet Oncology, The | 2019 | 254 |
| 21 | Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis | New England Journal of Medicine | 2015 | 245 |
| 22 | Antigen receptor repertoire profiling from RNA-seq data | Nature Biotechnology | 2017 | 243 |
| 23 | Simeprevir Increases Rate of Sustained Virologic Response Among Treatment-Experienced Patients With HCV Genotype-1 Infection: A Phase IIb Trial | Gastroenterology | 2014 | 217 |
| 24 | Risk factors for post-COVID-19 condition in previously hospitalised children using the ISARIC Global follow-up protocol: a prospective cohort study | European Respiratory Journal | 2022 | 216 |
| 25 | The genetics of Pak | Journal of Cell Science | 2004 | 215 |
| 26 | Ultrasensitive Genetically Encoded Indicator for Hydrogen Peroxide Identifies Roles for the Oxidant in Cell Migration and Mitochondrial Function | Cell Metabolism | 2020 | 202 |
| 27 | Photobiological Principles of Therapeutic Applications of Laser Radiation | Biochemistry (Moscow) | 2004 | 182 |
| 28 | High-quality full-length immunoglobulin profiling with unique molecular barcoding | Nature Protocols | 2016 | 179 |
| 29 | Enhancement of antioxidant and anti-inflammatory activities of bioflavonoid rutin by complexation with transition metals | Biochemical Pharmacology | 2001 | 174 |
| 30 | Umbilical Cord as Prospective Source for Mesenchymal Stem Cell-Based Therapy | Stem Cells International | 2016 | 169 |
| 31 | Discriminant analysis is an inappropriate method of authentication | TrAC - Trends in Analytical Chemistry | 2016 | 167 |
| 32 | The probiotic Escherichia coli strain Nissle 1917 (EcN) stops acute diarrhoea in infants and toddlers | European Journal of Pediatrics | 2007 | 164 |
| 33 | Validation of the Multiple Sclerosis International Quality of Life questionnaire | Multiple Sclerosis Journal | 2008 | 159 |
| 34 | Cell Cycle–Dependent Ciliogenesis and Cancer | Cancer Research | 2008 | 157 |
| 35 | Guidelines for the use of EEG methodology in the diagnosis of epilepsy | Acta Neurologica Scandinavica | 2002 | 150 |
| 36 | Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia | Translational Psychiatry | 2017 | 150 |
| 37 | The global burden of chronic urticaria for the patient and society* | British Journal of Dermatology | 2021 | 150 |
| 38 | Long-Term Use of Everolimus in Patients with Tuberous Sclerosis Complex: Final Results from the EXIST-1 Study | PLoS ONE | 2016 | 146 |
| 39 | Existing and Emerging Biomarkers for Immune Checkpoint Immunotherapy in Solid Tumors | Advances in Therapy | 2019 | 145 |
| 40 | Risdiplam-Treated Infants with Type 1 Spinal Muscular Atrophy versus Historical Controls | New England Journal of Medicine | 2021 | 137 |
| 41 | Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA) | World Journal of Emergency Surgery | 2016 | 130 |
| 42 | Genetically encodable bioluminescent system from fungi | Proceedings of the National Academy of Sciences of the United States of America | 2018 | 130 |
| 43 | Factors influencing on quality of life in people with epilepsy | Seizure: the Journal of the British Epilepsy Association | 2007 | 126 |
| 44 | Gadd45 proteins: Relevance to aging, longevity and age-related pathologies | Ageing Research Reviews | 2012 | 126 |
| 45 | Epilepsy in tuberous sclerosis complex: Findings from the TOSCA Study | Epilepsia Open | 2019 | 125 |
| 46 | Delivery of doxorubicin-loaded PLGA nanoparticles into U87 human glioblastoma cells | International Journal of Pharmaceutics | 2017 | 122 |
| 47 | Lung function and asthma control with beclomethasone and formoterol in a single inhaler | Respiratory Medicine | 2009 | 119 |
| 48 | NEDD9 Promotes Oncogenic Signaling in Mammary Tumor Development | Cancer Research | 2009 | 117 |
| 49 | Impact of COVID-19 on Pediatric Asthma: Practice Adjustments and Disease Burden | Journal of Allergy and Clinical Immunology: in Practice | 2020 | 117 |
| 50 | CLC-Pred: A freely available web-service for in silico prediction of human cell line cytotoxicity for drug-like compounds | PLoS ONE | 2018 | 116 |
