| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 2 | Development of series of gateway binary vectors, pGWBs, for realizing efficient construction of fusion genes for plant transformation | Journal of Bioscience and Bioengineering | 2007 | 1,492 |
| 3 | Engineered GFP as a vital reporter in plants | Current Biology | 1996 | 1,322 |
| 4 | Regulation of drought tolerance by gene manipulation of 9-cis-epoxycarotenoid dioxygenase, a key enzyme in abscisic acid biosynthesis in Arabidopsis | Plant Journal | 2001 | 1,138 |
| 5 | Targeted nucleotide editing using hybrid prokaryotic and vertebrate adaptive immune systems | Science | 2016 | 1,011 |
| 6 | Formulation design for poorly water-soluble drugs based on biopharmaceutics classification system: Basic approaches and practical applications | International Journal of Pharmaceutics | 2011 | 920 |
| 7 | Minimum Information about a Biosynthetic Gene cluster | Nature Chemical Biology | 2015 | 715 |
| 8 | Antioxidant activity of propolis of various geographic origins | Food Chemistry | 2004 | 692 |
| 9 | Isolation of drug-resistant H5N1 virus | Nature | 2005 | 633 |
| 10 | Dietary Intakes of Flavonols, Flavones and Isoflavones by Japanese Women and the Inverse Correlation between Quercetin Intake and Plasma LDL Cholesterol Concentration | Journal of Nutrition | 2000 | 627 |
| 11 | Haemagglutinin mutations responsible for the binding of H5N1 influenza A viruses to human-type receptors | Nature | 2006 | 594 |
| 12 | Functional Analysis and DNA Polymorphism of the Tandemly Repeated Sequences in the 5'-terminal Regulatory Region of the Human Gene for Thymidylate Synthase. | Cell Structure and Function | 1995 | 515 |
| 13 | Manganese action in brain function | Brain Research Reviews | 2003 | 481 |
| 14 | Comparison of complete amino acid sequences and receptor-binding properties among 13 serotypes of hemagglutinins of influenza A viruses | Virology | 1991 | 467 |
| 15 | Simplified nutritional screening tools for patients on maintenance hemodialysis | American Journal of Clinical Nutrition | 2008 | 459 |
| 16 | Sialic Acid Species as a Determinant of the Host Range of Influenza A Viruses | Journal of Virology | 2000 | 449 |
| 17 | Recognition, Neutralization, and Clearance of Target Peptides in the Bloodstream of Living Mice by Molecularly Imprinted Polymer Nanoparticles: A Plastic Antibody | Journal of the American Chemical Society | 2010 | 437 |
| 18 | Enhanced virulence of influenza A viruses with the haemagglutinin of the 1918 pandemic virus | Nature | 2004 | 434 |
| 19 | Blocking links to minimize contamination spread in a social network | ACM Transactions on Knowledge Discovery From Data | 2009 | 425 |
| 20 | Insulin secretion from pancreatic B cells caused by L-arginine-derived nitrogen oxides | Science | 1992 | 419 |
| 21 | Antisense suppression of proline degradation improves tolerance to freezing and salinity in Arabidopsis thaliana | FEBS Letters | 1999 | 405 |
| 22 | Tyrosine Phosphorylation of β-Catenin and Plakoglobin Enhanced by Hepatocyte Growth Factor and Epidermal Growth Factor in Human Carcinoma Cells | Cell Adhesion and Communication | 1994 | 402 |
| 23 | Short-chain fatty acid receptor, GPR43, is expressed by enteroendocrine cells and mucosal mast cells in rat intestine | Cell and Tissue Research | 2006 | 384 |
| 24 | Non-invasive quantitative detection and applications of non-toxic, S65T-type green fluorescent protein in living plants | Plant Journal | 1999 | 381 |
| 25 | Sialobiology of Influenza: Molecular Mechanism of Host Range Variation of Influenza Viruses | Biological and Pharmaceutical Bulletin | 2005 | 378 |
| 26 | Green-fluorescent protein as a new vital marker in plant cells | Plant Journal | 1995 | 375 |
| 27 | Simple and Easy Method to Evaluate Uptake Potential of Nanoparticles in Mammalian Cells Using a Flow Cytometric Light Scatter Analysis | Environmental Science & Technology | 2007 | 369 |
| 28 | Innovative Preparation of Curcumin for Improved Oral Bioavailability | Biological and Pharmaceutical Bulletin | 2011 | 364 |
| 29 | Movement of zinc and its functional significance in the brain | Brain Research Reviews | 2000 | 348 |
| 30 | Role of zinc in bone formation and bone resorption | Journal of Trace Elements in Experimental Medicine | 1998 | 346 |
| 31 | Intestinal absorption of luteolin and luteolin 7-O -β-glucoside in rats and humans | FEBS Letters | 1998 | 336 |
| 32 | Autophagy in Development and Stress Responses of Plants | Autophagy | 2006 | 327 |
| 33 | Biological functions of proline in morphogenesis and osmotolerance revealed in antisense transgenic Arabidopsis thaliana | Plant Journal | 1999 | 323 |
| 34 | Relaxation and immunity enhancement effects of γ‐Aminobutyric acid (GABA) administration in humans | BioFactors | 2006 | 318 |
| 35 | Reduced growth, abnormal kidney structure, and type 2 (AT2) angiotensin receptor-mediated blood pressure regulation in mice lacking both AT1A and AT1B receptors for angiotensin II | Proceedings of the National Academy of Sciences of the United States of America | 1998 | 308 |
| 36 | Zinc homeostasis and functions of zinc in the brain | BioMetals | 2001 | 302 |
| 37 | A Recessive Arabidopsis Mutant That Grows Photoautotrophically under Salt Stress Shows Enhanced Active Oxygen Detoxification | Plant Cell | 1999 | 299 |
| 38 | The contribution of azo dyes to the mutagenic activity of the Cristais River | Chemosphere | 2005 | 299 |
| 39 | Oxidative Cyclization in Natural Product Biosynthesis | Chemical Reviews | 2017 | 288 |
| 40 | CRISPR-Mediated Gene Editing to Assess the Roles of Tet2 and Dnmt3a in Clonal Hematopoiesis and Cardiovascular Disease | Circulation Research | 2018 | 282 |
| 41 | Conserved domain structure of pentatricopeptide repeat proteins involved in chloroplast RNA editing | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 280 |
| 42 | Expression of the short-chain fatty acid receptor, GPR43, in the human colon | Journal of Molecular Histology | 2008 | 274 |
| 43 | Nanodrugs: pharmacokinetics and safety | International Journal of Nanomedicine | 2014 | 274 |
| 44 | Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children. | Journal of Clinical Investigation | 1988 | 274 |
| 45 | Immobilization stress reduced the expression of neurotrophins and their receptors in the rat brain | Neuroscience Research | 1997 | 272 |
| 46 | Tea Catechins Prevent the Development of Atherosclerosis in Apoprotein E–Deficient Mice | Journal of Nutrition | 2001 | 272 |
| 47 | Expression of short-chain fatty acid receptor GPR41 in the human colon | Biomedical Research | 2009 | 266 |
| 48 | Antioxidant Activity of Polyphenols in Carob Pods | Journal of Agricultural and Food Chemistry | 2002 | 265 |
| 49 | SOFIE project – 3D shaking table test on a seven‐storey full‐scale cross‐laminated timber building | Earthquake Engineering and Structural Dynamics | 2013 | 265 |
| 50 | Japanese Intake of Flavonoids and Isoflavonoids from Foods | Journal of Epidemiology | 1998 | 264 |
