| # | Title | Journal | Year | Citations |
|---|
| 1 | The Internet of Things: A survey | Computer Networks | 2010 | 11,690 |
| 2 | Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. | Proceedings of the National Academy of Sciences of the United States of America | 1988 | 4,185 |
| 3 | Definition and classification of cancer cachexia: an international consensus | Lancet Oncology, The | 2011 | 4,015 |
| 4 | Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease | Nature Genetics | 2013 | 3,741 |
| 5 | Spontaneous polarization and piezoelectric constants of III-V nitrides | Physical Review B | 1997 | 2,662 |
| 6 | Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease | Nature Genetics | 2009 | 2,155 |
| 7 | Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease | Nature | 2003 | 1,980 |
| 8 | Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing | Nature Genetics | 2019 | 1,962 |
| 9 | Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease | Nature Genetics | 2011 | 1,708 |
| 10 | Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. | Proceedings of the National Academy of Sciences of the United States of America | 1994 | 1,343 |
| 11 | Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia | New England Journal of Medicine | 2013 | 1,284 |
| 12 | Scaling and criticality in a stochastic multi-agent model of a financial market | Nature | 1999 | 1,263 |
| 13 | Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS | Neuron | 2010 | 1,100 |
| 14 | Biological applications of magnetic nanoparticles | Chemical Society Reviews | 2012 | 1,079 |
| 15 | Cannabinoid and Heroin Activation of Mesolimbic Dopamine Transmission by a Common µ1 Opioid Receptor Mechanism | Science | 1997 | 1,059 |
| 16 | Consolidation/synthesis of materials by electric current activated/assisted sintering | Materials Science and Engineering Reports | 2009 | 1,047 |
| 17 | The Social Internet of Things (SIoT) – When social networks meet the Internet of Things: Concept, architecture and network characterization | Computer Networks | 2012 | 1,041 |
| 18 | TRY plant trait database – enhanced coverage and open access | Global Change Biology | 2020 | 1,038 |
| 19 | Applications of Supramolecular Anion Recognition | Chemical Reviews | 2015 | 1,025 |
| 20 | Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs | Nature | 1996 | 1,015 |
| 21 | Chattering avoidance by second-order sliding mode control | IEEE Transactions on Automatic Control | 1998 | 957 |
| 22 | Hallmarks of mechanochemistry: from nanoparticles to technology | Chemical Society Reviews | 2013 | 952 |
| 23 | Beta-thalassemia | Orphanet Journal of Rare Diseases | 2010 | 924 |
| 24 | Bone Dysplasia Sclerosteosis Results from Loss of the SOST Gene Product, a Novel Cystine Knot–Containing Protein | American Journal of Human Genetics | 2001 | 912 |
| 25 | The putative forkhead transcription factor FOXL2 is mutated in blepharophimosis/ptosis/epicanthus inversus syndrome | Nature Genetics | 2001 | 886 |
| 26 | Pyroelectric properties of Al(In)GaN/GaN hetero- and quantum well structures | Journal of Physics Condensed Matter | 2002 | 864 |
| 27 | Immunosuppressive therapy in lupus nephritis: The Euro-Lupus Nephritis Trial, a randomized trial of low-dose versus high-dose intravenous cyclophosphamide | Arthritis and Rheumatism | 2002 | 849 |
| 28 | Nucleus accumbens shell and core dopamine: differential role in behavior and addiction | Behavioural Brain Research | 2002 | 840 |
| 29 | Tracing European Founder Lineages in the Near Eastern mtDNA Pool | American Journal of Human Genetics | 2000 | 837 |
| 30 | Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases | Frontiers in Physiology | 2020 | 833 |
| 31 | Tests of General Relativity from Timing the Double Pulsar | Science | 2006 | 817 |
| 32 | The Outcome of Acute Hepatitis C Predicted by the Evolution of the Viral Quasispecies | Science | 2000 | 810 |
| 33 | An increased estimate of the merger rate of double neutron stars from observations of a highly relativistic system | Nature | 2003 | 806 |
| 34 | Intravenous cocaine, morphine, and amphetamine preferentially increase extracellular dopamine in the "shell" as compared with the "core" of the rat nucleus accumbens. | Proceedings of the National Academy of Sciences of the United States of America | 1995 | 783 |
| 35 | Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease | Nature Genetics | 2017 | 783 |
| 36 | In-vitro antimicrobial activity and chemical composition of Sardinian Thymus essential oils | Letters in Applied Microbiology | 1999 | 782 |
| 37 | Dopamine and drug addiction: the nucleus accumbens shell connection | Neuropharmacology | 2004 | 777 |
| 38 | Evidence for nonlinear macroscopic polarization in III–V nitride alloy heterostructures | Applied Physics Letters | 2002 | 746 |
| 39 | Mutations in GPC3, a glypican gene, cause the Simpson-Golabi-Behmel overgrowth syndrome | Nature Genetics | 1996 | 732 |
| 40 | Group for Research and Assessment of Psoriasis and Psoriatic Arthritis 2015 Treatment Recommendations for Psoriatic Arthritis | Arthritis and Rheumatology | 2016 | 726 |
| 41 | Low doses of ethanol activate dopaminergic neurons in the ventral tegmental area | Brain Research | 1985 | 725 |
| 42 | Reduction of hospitalizations for myocardial infarction in Italy in the COVID-19 era | European Heart Journal | 2020 | 716 |
| 43 | Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats | Journal of Pharmacology and Experimental Therapeutics | 1988 | 711 |
| 44 | The Role of Ligands in the Chemical Synthesis and Applications of Inorganic Nanoparticles | Chemical Reviews | 2019 | 709 |
| 45 | New insights into the genetic etiology of Alzheimer’s disease and related dementias | Nature Genetics | 2022 | 700 |
| 46 | Iron(iii) selective molecular and supramolecular fluorescent probes | Chemical Society Reviews | 2012 | 688 |
| 47 | Evasion Attacks against Machine Learning at Test Time | Lecture Notes in Computer Science | 2013 | 678 |
| 48 | Beta-caryophyllene is a dietary cannabinoid | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 664 |
| 49 | Wild patterns: Ten years after the rise of adversarial machine learning | Pattern Recognition | 2018 | 658 |
| 50 | Evolution of public attitudes about mental illness: a systematic review and meta‐analysis | Acta Psychiatrica Scandinavica | 2012 | 648 |
