| # | Title | Journal | Year | Citations |
|---|
| 1 | 2012 Revised International Chapel Hill Consensus Conference Nomenclature of Vasculitides | Arthritis and Rheumatism | 2013 | 4,839 |
| 2 | Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease | Nature | 2012 | 4,038 |
| 3 | Genetic studies of body mass index yield new insights for obesity biology | Nature | 2015 | 3,823 |
| 4 | The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism | Journal of Lipid Research | 2013 | 3,292 |
| 5 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 6 | Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders | Nature | 2011 | 2,806 |
| 7 | Discovery and refinement of loci associated with lipid levels | Nature Genetics | 2013 | 2,641 |
| 8 | A reference panel of 64,976 haplotypes for genotype imputation | Nature Genetics | 2016 | 2,421 |
| 9 | Low-density lipoproteins cause atherosclerotic cardiovascular disease. 1. Evidence from genetic, epidemiologic, and clinical studies. A consensus statement from the European Atherosclerosis Society Consensus Panel | European Heart Journal | 2017 | 2,292 |
| 10 | Transfer of Intestinal Microbiota From Lean Donors Increases Insulin Sensitivity in Individuals With Metabolic Syndrome | Gastroenterology | 2012 | 2,287 |
| 11 | Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci | Nature Genetics | 2010 | 2,284 |
| 12 | Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression | Nature Genetics | 2018 | 2,224 |
| 13 | Prevalence of Frailty in Community‐Dwelling Older Persons: A Systematic Review | Journal of the American Geriatrics Society | 2012 | 2,125 |
| 14 | Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics | PLoS Genetics | 2014 | 2,012 |
| 15 | Genetics of rheumatoid arthritis contributes to biology and drug discovery | Nature | 2014 | 1,974 |
| 16 | Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations | Nature Genetics | 2015 | 1,965 |
| 17 | Environment dominates over host genetics in shaping human gut microbiota | Nature | 2018 | 1,958 |
| 18 | Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases | Frontiers in Immunology | 2019 | 1,956 |
| 19 | Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study | Lancet, The | 2012 | 1,937 |
| 20 | Childhood adversities and adult psychopathology in the WHO World Mental Health Surveys | British Journal of Psychiatry | 2010 | 1,854 |
| 21 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 22 | Population-level analysis of gut microbiome variation | Science | 2016 | 1,716 |
| 23 | Structural Variation of Chromosomes in Autism Spectrum Disorder | American Journal of Human Genetics | 2008 | 1,641 |
| 24 | iRECIST: guidelines for response criteria for use in trials testing immunotherapeutics | Lancet Oncology, The | 2017 | 1,612 |
| 25 | The Determinants of Quality of Life of Nursing Home Residents with Young-Onset Dementia and the Differences between Dementia Subtypes | Dementia and Geriatric Cognitive Disorders | 2017 | 1,595 |
| 26 | The Human Cell Atlas | ELife | 2017 | 1,547 |
| 27 | Systematic identification of trans eQTLs as putative drivers of known disease associations | Nature Genetics | 2013 | 1,544 |
| 28 | mTOR- and HIF-1α–mediated aerobic glycolysis as metabolic basis for trained immunity | Science | 2014 | 1,517 |
| 29 | Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: an open-label, randomised, controlled trial | Lancet, The | 2013 | 1,491 |
| 30 | TFOS DEWS II Epidemiology Report | Ocular Surface | 2017 | 1,490 |
| 31 | Angiotensin–Neprilysin Inhibition in Heart Failure with Preserved Ejection Fraction | New England Journal of Medicine | 2019 | 1,485 |
| 32 | Hallmarks of Cellular Senescence | Trends in Cell Biology | 2018 | 1,474 |
| 33 | Stress, memory and the amygdala | Nature Reviews Neuroscience | 2009 | 1,430 |
| 34 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 35 | Effects of COVID-19 Home Confinement on Eating Behaviour and Physical Activity: Results of the ECLB-COVID19 International Online Survey | Nutrients | 2020 | 1,414 |
| 36 | Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 1,398 |
| 37 | Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion | Autophagy | 2018 | 1,341 |
| 38 | Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity | Science | 2014 | 1,338 |
| 39 | New genetic loci link adipose and insulin biology to body fat distribution | Nature | 2015 | 1,328 |
| 40 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016 | JAMA Oncology | 2018 | 1,260 |
| 41 | Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial | Lancet, The | 2008 | 1,239 |
| 42 | Toxicity of nanomaterials | Chemical Society Reviews | 2012 | 1,221 |
| 43 | The neuroactive potential of the human gut microbiota in quality of life and depression | Nature Microbiology | 2019 | 1,206 |
| 44 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 45 | Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 | Nature Genetics | 2011 | 1,201 |
| 46 | RECIST 1.1—Update and clarification: From the RECIST committee | European Journal of Cancer | 2016 | 1,143 |
| 47 | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes | Nature Genetics | 2018 | 1,124 |
| 48 | Genome-wide association study identifies eight loci associated with blood pressure | Nature Genetics | 2009 | 1,104 |
| 49 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 50 | Preoperative Staging of Non–Small-Cell Lung Cancer with Positron-Emission Tomography | New England Journal of Medicine | 2000 | 1,052 |
