| # | Title | Journal | Year | Citations |
|---|
| 1 | Common variants conferring risk of schizophrenia | Nature | 2009 | 1,572 |
| 2 | Genome-wide association analysis identifies 13 new risk loci for schizophrenia | Nature Genetics | 2013 | 1,395 |
| 3 | Afatinib versus cisplatin-based chemotherapy for EGFR mutation-positive lung adenocarcinoma (LUX-Lung 3 and LUX-Lung 6): analysis of overall survival data from two randomised, phase 3 trials | Lancet Oncology, The | 2015 | 1,369 |
| 4 | Recovery from psychotic illness: A 15- and 25-year international follow-up study | British Journal of Psychiatry | 2001 | 873 |
| 5 | A comparative study of the anti-inflammatory, anticoagulant, antiangiogenic, and antiadhesive activities of nine different fucoidans from brown seaweeds | Glycobiology | 2007 | 844 |
| 6 | Upper Palaeolithic Siberian genome reveals dual ancestry of Native Americans | Nature | 2014 | 821 |
| 7 | Atomic force microscopy probing of cell elasticity | Micron | 2007 | 662 |
| 8 | Human anterior and frontal midline theta and lower alpha reflect emotionally positive state and internalized attention: high-resolution EEG investigation of meditation | Neuroscience Letters | 2001 | 651 |
| 9 | Prediction of the Biological Activity Spectra of Organic Compounds Using the Pass Online Web Resource | Chemistry of Heterocyclic Compounds | 2014 | 630 |
| 10 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 11 | Tobacco and Cancer: Recent Epidemiological Evidence | Journal of the National Cancer Institute | 2004 | 594 |
| 12 | Linifanib Versus Sorafenib in Patients With Advanced Hepatocellular Carcinoma: Results of a Randomized Phase III Trial | Journal of Clinical Oncology | 2015 | 517 |
| 13 | Dating the Origin of the CCR5-Δ32 AIDS-Resistance Allele by the Coalescence of Haplotypes | American Journal of Human Genetics | 1998 | 507 |
| 14 | Beringian Standstill and Spread of Native American Founders | PLoS ONE | 2007 | 499 |
| 15 | Delayed regional lymph node dissection in stage I melanoma of the skin of the lower extremities | Cancer | 1982 | 484 |
| 16 | Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14 | Nature Genetics | 1992 | 472 |
| 17 | Cysteine proteases of positive strand RNA viruses and chymotrypsin-like serine proteases | FEBS Letters | 1989 | 457 |
| 18 | Mitochondrial aspartyl-tRNA synthetase deficiency causes leukoencephalopathy with brain stem and spinal cord involvement and lactate elevation | Nature Genetics | 2007 | 415 |
| 19 | Neoadjuvant and adjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer (NOAH): follow-up of a randomised controlled superiority trial with a parallel HER2-negative cohort | Lancet Oncology, The | 2014 | 406 |
| 20 | Mechanisms of foam cell formation in atherosclerosis | Journal of Molecular Medicine | 2017 | 406 |
| 21 | Phase III, randomised trial of avelumab versus physician’s choice of chemotherapy as third-line treatment of patients with advanced gastric or gastro-oesophageal junction cancer: primary analysis of JAVELIN Gastric 300 | Annals of Oncology | 2018 | 387 |
| 22 | Effect of Metformin in Pediatric Patients With Type 2 Diabetes | Diabetes Care | 2002 | 379 |
| 23 | The genome-wide structure of the Jewish people | Nature | 2010 | 369 |
| 24 | Towards a new developmental synthesis: adaptive developmental plasticity and human disease | Lancet, The | 2009 | 368 |
| 25 | Avian Influenza A Viruses Differ from Human Viruses by Recognition of Sialyloligosaccharides and Gangliosides and by a Higher Conservation of the HA Receptor-Binding Site | Virology | 1997 | 365 |
| 26 | Conservation of the putative methyltransferase domain: a hallmark of the 'Sindbis-like' supergroup of positive-strand RNA viruses | Journal of General Virology | 1992 | 361 |
| 27 | An attempt to prevent senescence: A mitochondrial approach | Biochimica Et Biophysica Acta - Bioenergetics | 2009 | 359 |
| 28 | Interpreting EEG alpha activity | Neuroscience and Biobehavioral Reviews | 2014 | 349 |
| 29 | Effects and safety of rituximab in systemic sclerosis: an analysis from the European Scleroderma Trial and Research (EUSTAR) group | Annals of the Rheumatic Diseases | 2015 | 340 |
| 30 | Ancient DNA from European Early Neolithic Farmers Reveals Their Near Eastern Affinities | PLoS Biology | 2010 | 339 |
| 31 | BRAF mutations are associated with some histological types of papillary thyroid carcinoma | Journal of Pathology | 2004 | 334 |
| 32 | Sexual behaviours and the risk of head and neck cancers: a pooled analysis in the International Head and Neck Cancer Epidemiology (INHANCE) consortium | International Journal of Epidemiology | 2010 | 322 |
| 33 | Management of Pediatric Ulcerative Colitis | Journal of Pediatric Gastroenterology and Nutrition | 2012 | 320 |
| 34 | Muscle volume, MRI relaxation times (T2), and body composition after spaceflight | Journal of Applied Physiology | 2000 | 315 |
| 35 | Effects of shear stress on endothelial cells: go with the flow | Acta Physiologica | 2017 | 310 |
| 36 | Baricitinib, Methotrexate, or Combination in Patients With Rheumatoid Arthritis and No or Limited Prior Disease‐Modifying Antirheumatic Drug Treatment | Arthritis and Rheumatology | 2017 | 310 |
| 37 | The role of mitochondrial dysfunction in cardiovascular disease: a brief review | Annals of Medicine | 2018 | 299 |
| 38 | Systematic Review and Meta-analysis of Circulatory Disease from Exposure to Low-Level Ionizing Radiation and Estimates of Potential Population Mortality Risks | Environmental Health Perspectives | 2012 | 296 |
| 39 | Distinct and Nonredundant In Vivo Functions of TNF Produced by T Cells and Macrophages/Neutrophils | Immunity | 2005 | 294 |
| 40 | The Human Proteome Project: Current State and Future Direction | Molecular and Cellular Proteomics | 2011 | 294 |
| 41 | Genome-wide association study reveals two new risk loci for bipolar disorder | Nature Communications | 2014 | 294 |
| 42 | Bactericidal effects of non-thermal argon plasma in vitro, in biofilms and in the animal model of infected wounds | Journal of Medical Microbiology | 2011 | 293 |
| 43 | EFNS guideline on mild traumatic brain injury: report of an EFNS task force | European Journal of Neurology | 2002 | 287 |
| 44 | A novel superfamily of nucleoside triphosphate-binding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination | FEBS Letters | 1988 | 278 |
| 45 | Determinants of cardiovascular disease and other non-communicable diseases in Central and Eastern Europe: Rationale and design of the HAPIEE study | BMC Public Health | 2006 | 269 |
| 46 | Deficiency in the Ubiquitin Conjugating Enzyme UBE2A in Alzheimer’s Disease (AD) is Linked to Deficits in a Natural Circular miRNA-7 Sponge (circRNA; ciRS-7) | Genes | 2016 | 266 |
| 47 | Factors required for bone marrow stromal fibroblast colony formation in vitro | British Journal of Haematology | 1997 | 263 |
| 48 | Essential role for cholesterol in synaptic plasticity and neuronal degeneration | FASEB Journal | 2001 | 260 |
| 49 | Drug delivery to the brain using surfactant-coated poly(lactide-co-glycolide) nanoparticles: Influence of the formulation parameters | European Journal of Pharmaceutics and Biopharmaceutics | 2010 | 260 |
| 50 | Mechanisms of angiogenesis | Biochemistry (Moscow) | 2008 | 259 |
