| # | Title | Journal | Year | Citations |
|---|
| 1 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 2 | Effect of Gene Therapy on Visual Function in Leber's Congenital Amaurosis | New England Journal of Medicine | 2008 | 1,793 |
| 3 | Primary open-angle glaucoma | Lancet, The | 2004 | 1,728 |
| 4 | OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28 | Nature Genetics | 2000 | 1,169 |
| 5 | An Integrated Hypothesis That Considers Drusen as Biomarkers of Immune-Mediated Processes at the RPE-Bruch's Membrane Interface in Aging and Age-Related Macular Degeneration | Progress in Retinal and Eye Research | 2001 | 1,162 |
| 6 | Systematic Review of the Empirical Evidence of Study Publication Bias and Outcome Reporting Bias | PLoS ONE | 2008 | 1,142 |
| 7 | ISCEV Standard for full-field clinical electroretinography (2015 update) | Documenta Ophthalmologica | 2015 | 1,103 |
| 8 | Adult-Onset Primary Open-Angle Glaucoma Caused by Mutations in Optineurin | Science | 2002 | 962 |
| 9 | ISCEV Standard for full-field clinical electroretinography (2008 update) | Documenta Ophthalmologica | 2009 | 867 |
| 10 | Artificial intelligence and deep learning in ophthalmology | British Journal of Ophthalmology | 2019 | 754 |
| 11 | ISCEV standard for clinical visual evoked potentials (2009 update) | Documenta Ophthalmologica | 2010 | 707 |
| 12 | Mapping the visual field to the optic disc in normal tension glaucoma eyes11The authors have no proprietary interest in the development or marketing of any product or instrument mentioned in this article. | Ophthalmology | 2000 | 640 |
| 13 | Memantine for dementia | The Cochrane Library | 2006 | 608 |
| 14 | Cataracts | Lancet, The | 2017 | 580 |
| 15 | Mutations in the human retinal degeneration slow (RDS) gene can cause either retinitis pigmentosa or macular dystrophy | Nature Genetics | 1993 | 483 |
| 16 | Retinal nerve fiber layer axonal loss and visual dysfunction in optic neuritis | Annals of Neurology | 2005 | 477 |
| 17 | Multi-country real-life experience of anti-vascular endothelial growth factor therapy for wet age-related macular degeneration | British Journal of Ophthalmology | 2015 | 474 |
| 18 | A Prospective Randomized Trial of Intravitreal Bevacizumab or Laser Therapy in the Management of Diabetic Macular Edema (BOLT Study) | Ophthalmology | 2010 | 473 |
| 19 | Distribution of fundus autofluorescence with a scanning laser ophthalmoscope. | British Journal of Ophthalmology | 1995 | 469 |
| 20 | Mutations in SOX2 cause anophthalmia | Nature Genetics | 2003 | 466 |
| 21 | Adverse Effects of Topical Antiglaucoma Medication | JAMA Ophthalmology | 1994 | 461 |
| 22 | A gene (RPGR) with homology to the RCC1 guanine nucleotide exchange factor is mutated in X–linked retinitis pigmentosa (RP3) | Nature Genetics | 1996 | 453 |
| 23 | A single EFEMP1 mutation associated with both Malattia Leventinese and Doyne honeycomb retinal dystrophy | Nature Genetics | 1999 | 453 |
| 24 | ISCEV standard for clinical pattern electroretinography (PERG): 2012 update | Documenta Ophthalmologica | 2013 | 449 |
| 25 | Guidelines on Diabetic Eye Care | Ophthalmology | 2018 | 437 |
| 26 | Changes in Collagen Orientation and Distribution in Keratoconus Corneas | Ophthalmology | 2005 | 424 |
| 27 | Fruits and vegetables that are sources for lutein and zeaxanthin: the macular pigment in human eyes | British Journal of Ophthalmology | 1998 | 423 |
| 28 | Standard for clinical electroretinography (2004 update) | Documenta Ophthalmologica | 2004 | 422 |
| 29 | Retinopathy of prematurity in middle-income countries | Lancet, The | 1997 | 420 |
| 30 | Corneal Thickness- and Age-Related Biomechanical Properties of the Cornea Measured with the Ocular Response Analyzer | Lancet, The | 2006 | 396 |
| 31 | Protective Effects of Human iPS-Derived Retinal Pigment Epithelium Cell Transplantation in the Retinal Dystrophic Rat | PLoS ONE | 2009 | 382 |
| 32 | Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1 | Nature Genetics | 2011 | 381 |
| 33 | Identification of early glaucoma cases with the scanning laser ophthalmoscope11The authors have no proprietary interest in the development or marketing of this or a competing instrument. | Ophthalmology | 1998 | 380 |
| 34 | Syphilis and HIV: a dangerous combination | Lancet Infectious Diseases, The | 2004 | 369 |
| 35 | Contact lenses and other risk factors in microbial keratitis | Lancet, The | 1991 | 365 |
| 36 | A Missense Mutation in the Human Connexin50 Gene (GJA8) Underlies Autosomal Dominant “Zonular Pulverulent” Cataract, on Chromosome 1q | American Journal of Human Genetics | 1998 | 358 |
| 37 | Long-term Functional Outcome after Early Surgery Compared with Laser and Medicine in Open-angle Glaucoma | Ophthalmology | 1994 | 348 |
| 38 | The epidemiology of rhegmatogenous retinal detachment: geographical variation and clinical associations | British Journal of Ophthalmology | 2010 | 348 |
| 39 | A 2-Year Prospective Randomized Controlled Trial of Intravitreal Bevacizumab or Laser Therapy (BOLT) in the Management of Diabetic Macular Edema | JAMA Ophthalmology | 2012 | 347 |
| 40 | Outdoor activity and myopia in Singapore teenage children | British Journal of Ophthalmology | 2009 | 345 |
| 41 | Comprehensive Rare Variant Analysis via Whole-Genome Sequencing to Determine the Molecular Pathology of Inherited Retinal Disease | American Journal of Human Genetics | 2017 | 343 |
| 42 | Long-term Morphologic Effects of Antiglaucoma Drugs on the Conjunctiva and Tenon's Capsule in Glaucomatous Patients | Ophthalmology | 1989 | 337 |
| 43 | The Association between Time Spent Outdoors and Myopia in Children and Adolescents | Ophthalmology | 2012 | 337 |
| 44 | Prevalence and Clinical Characteristics of Glaucoma in Adult Chinese: A Population-Based Study in Liwan District, Guangzhou | Ophthalmology | 2006 | 334 |
| 45 | Comparison of deep lamellar keratoplasty and penetrating keratoplasty in patients with keratoconus | Ophthalmology | 2004 | 324 |
| 46 | Visual evoked potentials standard (2004) | Documenta Ophthalmologica | 2004 | 319 |
| 47 | Depression and Anxiety in Visually Impaired Older People | Ophthalmology | 2007 | 319 |
| 48 | Treatment of Chronic Macular Edema With Acetazolamide | JAMA Ophthalmology | 1988 | 318 |
| 49 | The Argus II epiretinal prosthesis system allows letter and word reading and long-term function in patients with profound vision loss | British Journal of Ophthalmology | 2013 | 316 |
| 50 | Prognostic Factors for the Progression of Keratoconus | Ophthalmology | 1994 | 310 |
