| # | Title | Journal | Year | Citations |
|---|
| 1 | Human papillomavirus genotype attribution in invasive cervical cancer: a retrospective cross-sectional worldwide study | Lancet Oncology, The | 2010 | 2,093 |
| 2 | The novel object recognition memory: neurobiology, test procedure, and its modifications | Cognitive Processing | 2012 | 1,643 |
| 3 | Click Chemistry for Drug Development and Diverse Chemical–Biology Applications | Chemical Reviews | 2013 | 1,534 |
| 4 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 5 | Lenalidomide plus Dexamethasone for Relapsed or Refractory Multiple Myeloma | New England Journal of Medicine | 2007 | 1,365 |
| 6 | First-line nivolumab plus chemotherapy versus chemotherapy alone for advanced gastric, gastro-oesophageal junction, and oesophageal adenocarcinoma (CheckMate 649): a randomised, open-label, phase 3 trial | Lancet, The | 2021 | 1,237 |
| 7 | Photodynamic therapy – mechanisms, photosensitizers and combinations | Biomedicine and Pharmacotherapy | 2018 | 1,221 |
| 8 | Multicenter, Randomized, Open-Label, Phase III Trial of Decitabine Versus Patient Choice, With Physician Advice, of Either Supportive Care or Low-Dose Cytarabine for the Treatment of Older Patients With Newly Diagnosed Acute Myeloid Leukemia | Journal of Clinical Oncology | 2012 | 998 |
| 9 | Oral Ixazomib, Lenalidomide, and Dexamethasone for Multiple Myeloma | New England Journal of Medicine | 2016 | 861 |
| 10 | Oxidative stress as a crucial factor in liver diseases | World Journal of Gastroenterology | 2014 | 802 |
| 11 | Gastric cancer: epidemiology, prevention, classification, and treatment | Cancer Management and Research | 2018 | 745 |
| 12 | Theoretical models of sorption kinetics including a surface reaction mechanism: A review | Advances in Colloid and Interface Science | 2009 | 741 |
| 13 | A consensus protocol for the standardization of cerebrospinal fluid collection and biobanking | Neurology | 2009 | 653 |
| 14 | Gastric Cancer: Epidemiology, Risk Factors, Classification, Genomic Characteristics and Treatment Strategies | International Journal of Molecular Sciences | 2020 | 639 |
| 15 | Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial | Lancet, The | 2011 | 458 |
| 16 | Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic Markers, and Current Treatment Strategies—An Updated Review | Cancers | 2021 | 441 |
| 17 | H2AX Phosphorylation: Its Role in DNA Damage Response and Cancer Therapy | Journal of Nucleic Acids | 2010 | 393 |
| 18 | Bioactivity of dietary polyphenols: The role of metabolites | Critical Reviews in Food Science and Nutrition | 2020 | 378 |
| 19 | COVID-19: ICU delirium management during SARS-CoV-2 pandemic | Critical Care | 2020 | 368 |
| 20 | Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity*1 | Clinical Pharmacology and Therapeutics | 2004 | 366 |
| 21 | The European Lead Extraction ConTRolled (ELECTRa) study: a European Heart Rhythm Association (EHRA) Registry of Transvenous Lead Extraction Outcomes | European Heart Journal | 2017 | 339 |
| 22 | Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial Assessing the Efficacy and Safety of Proton Pump Inhibitor Lansoprazole in Infants with Symptoms of Gastroesophageal Reflux Disease | Journal of Pediatrics | 2009 | 334 |
| 23 | Mechanisms of aromatase inhibitor resistance | Nature Reviews Cancer | 2015 | 319 |
| 24 | Luteolin as an anti-inflammatory and neuroprotective agent: A brief review | Brain Research Bulletin | 2015 | 317 |
| 25 | Long-course oxaliplatin-based preoperative chemoradiation versus 5 × 5 Gy and consolidation chemotherapy for cT4 or fixed cT3 rectal cancer: results of a randomized phase III study | Annals of Oncology | 2016 | 317 |
| 26 | Medication use in pregnancy: a cross-sectional, multinational web-based study | BMJ Open | 2014 | 311 |
| 27 | Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction | Nature Immunology | 2016 | 310 |
| 28 | Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: an international, double-blind, double-dummy, randomised, controlled, phase 3 study | Lancet Oncology, The | 2018 | 300 |
| 29 | Proportion of peripheral blood and decidual CD4+ CD25bright regulatory T cells in pre-eclampsia | Clinical and Experimental Immunology | 2007 | 299 |
| 30 | Bioengineered human acellular vessels for dialysis access in patients with end-stage renal disease: two phase 2 single-arm trials | Lancet, The | 2016 | 291 |
| 31 | Current Concepts and Treatments of Schizophrenia | Molecules | 2018 | 284 |
| 32 | Cancer SLC43A2 alters T cell methionine metabolism and histone methylation | Nature | 2020 | 280 |
| 33 | COVID-19: Specific and Non-Specific Clinical Manifestations and Symptoms: The Current State of Knowledge | Journal of Clinical Medicine | 2020 | 280 |
| 34 | Antioxidant Potential of Propolis, Bee Pollen, and Royal Jelly: Possible Medical Application | Oxidative Medicine and Cellular Longevity | 2018 | 268 |
| 35 | Efficacy and safety of tocilizumab in patients with polyarticular-course juvenile idiopathic arthritis: results from a phase 3, randomised, double-blind withdrawal trial | Annals of the Rheumatic Diseases | 2015 | 251 |
| 36 | Conversion from clinically isolated syndrome to multiple sclerosis: A large multicentre study | Multiple Sclerosis Journal | 2015 | 249 |
| 37 | ASCEND: Phase III, Randomized Trial of Acalabrutinib Versus Idelalisib Plus Rituximab or Bendamustine Plus Rituximab in Relapsed or Refractory Chronic Lymphocytic Leukemia | Journal of Clinical Oncology | 2020 | 235 |
| 38 | A review of recent developments and trends in the QuEChERS sample preparation approach | Open Chemistry | 2015 | 230 |
| 39 | IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer | Journal of Immunology | 2011 | 224 |
| 40 | The many “faces” of copper in medicine and treatment | BioMetals | 2014 | 224 |
| 41 | Myeloid-Derived Suppressor Cells Endow Stem-like Qualities to Breast Cancer Cells through IL6/STAT3 and NO/NOTCH Cross-talk Signaling | Cancer Research | 2016 | 224 |
| 42 | Magnetization Transfer Contrast and Chemical Exchange Saturation Transfer MRI. Features and analysis of the field-dependent saturation spectrum | NeuroImage | 2018 | 220 |
| 43 | Classification of Fundus Autofluorescence Patterns in Early Age-Related Macular Disease | | 2005 | 217 |
| 44 | Predicting the risk of malignancy in adnexal masses based on the Simple Rules from the International Ovarian Tumor Analysis group | American Journal of Obstetrics and Gynecology | 2016 | 212 |
| 45 | Oxygen causes cell death in the developing brain | Neurobiology of Disease | 2004 | 211 |
| 46 | Autosomal-Recessive Mutations in SLC34A1 Encoding Sodium-Phosphate Cotransporter 2A Cause Idiopathic Infantile Hypercalcemia | Journal of the American Society of Nephrology: JASN | 2016 | 207 |
| 47 | Influence of In Vitro Digestion on Composition, Bioaccessibility and Antioxidant Activity of Food Polyphenols—A Non-Systematic Review | Nutrients | 2020 | 206 |
| 48 | High Cholesterol/Low Cholesterol: Effects in Biological Membranes: A Review | Cell Biochemistry and Biophysics | 2017 | 204 |
| 49 | The role of microbiota-gut-brain axis in neuropsychiatric and neurological disorders | Pharmacological Research | 2021 | 201 |
| 50 | Modifications of dietary flavonoids towards improved bioactivity: An update on structure–activity relationship | Critical Reviews in Food Science and Nutrition | 2018 | 200 |
