| # | Title | Journal | Year | Citations |
|---|
| 1 | Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010 | Lancet, The | 2012 | 6,376 |
| 2 | The Metabolic Phenotype in Obesity: Fat Mass, Body Fat Distribution, and Adipose Tissue Function | Obesity Facts | 2017 | 5,743 |
| 3 | Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach | Chest | 2010 | 5,657 |
| 4 | Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials | Lancet, The | 2016 | 5,331 |
| 5 | Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration | Lancet Neurology, The | 2013 | 3,919 |
| 6 | Radiomics: Extracting more information from medical images using advanced feature analysis | European Journal of Cancer | 2012 | 3,846 |
| 7 | A Novel User-Friendly Score (HAS-BLED) To Assess 1-Year Risk of Major Bleeding in Patients With Atrial Fibrillation | Chest | 2010 | 3,810 |
| 8 | Radiomics: the bridge between medical imaging and personalized medicine | Nature Reviews Clinical Oncology | 2017 | 3,216 |
| 9 | Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human | Cell | 2012 | 2,740 |
| 10 | Advancing research diagnostic criteria for Alzheimer's disease: the IWG-2 criteria | Lancet Neurology, The | 2014 | 2,657 |
| 11 | Prediction models for diagnosis and prognosis of covid-19: systematic review and critical appraisal | BMJ, The | 2020 | 2,134 |
| 12 | Schizophrenia | Lancet, The | 2009 | 1,820 |
| 13 | Radiomics: the process and the challenges | Magnetic Resonance Imaging | 2012 | 1,675 |
| 14 | Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis | JAMA - Journal of the American Medical Association | 2016 | 1,617 |
| 15 | The Determinants of Quality of Life of Nursing Home Residents with Young-Onset Dementia and the Differences between Dementia Subtypes | Dementia and Geriatric Cognitive Disorders | 2017 | 1,595 |
| 16 | Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data | Lancet Oncology, The | 2010 | 1,532 |
| 17 | Short-chain fatty acids in control of body weight and insulin sensitivity | Nature Reviews Endocrinology | 2015 | 1,484 |
| 18 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 19 | Reduced cardiotoxicity and comparable efficacy in a phase IIItrial of pegylated liposomal doxorubicin HCl(CAELYX™/Doxil®) versus conventional doxorubicin forfirst-line treatment of metastatic breast cancer | Annals of Oncology | 2004 | 1,407 |
| 20 | Population-based metagenomics analysis reveals markers for gut microbiome composition and diversity | Science | 2016 | 1,398 |
| 21 | The environment and schizophrenia | Nature | 2010 | 1,249 |
| 22 | Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials | Lancet Oncology, The | 2015 | 1,220 |
| 23 | Intestinal permeability – a new target for disease prevention and therapy | BMC Gastroenterology | 2014 | 1,187 |
| 24 | Biallelic Inactivation of BRCA2 in Fanconi Anemia | Science | 2002 | 1,072 |
| 25 | Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans | Cell Metabolism | 2011 | 1,072 |
| 26 | Probing sporadic and familial Alzheimer’s disease using induced pluripotent stem cells | Nature | 2012 | 1,069 |
| 27 | Outpatient Psychotherapy for Borderline Personality Disorder | Archives of General Psychiatry | 2006 | 1,062 |
| 28 | Doxorubicin-induced cardiomyopathy: From molecular mechanisms to therapeutic strategies | Journal of Molecular and Cellular Cardiology | 2012 | 1,053 |
| 29 | Applying extracellular vesicles based therapeutics in clinical trials – an ISEV position paper | Journal of Extracellular Vesicles | 2015 | 1,020 |
| 30 | Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer | Frontiers in Microbiology | 2016 | 1,018 |
| 31 | ESPEN Guidelines on Enteral Nutrition: Surgery including Organ Transplantation | Clinical Nutrition | 2006 | 988 |
| 32 | The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: A meta-analysis of randomized controlled trials | Clinical Nutrition | 2010 | 986 |
| 33 | Characterisation of COPD heterogeneity in the ECLIPSE cohort | Respiratory Research | 2010 | 952 |
| 34 | Small-cell lung cancer | Lancet, The | 2011 | 941 |
| 35 | Mapping genomic loci implicates genes and synaptic biology in schizophrenia | Nature | 2022 | 929 |
| 36 | 2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours | European Journal of Cancer | 2011 | 895 |
| 37 | Wait-and-See Policy for Clinical Complete Responders After Chemoradiation for Rectal Cancer | Journal of Clinical Oncology | 2011 | 893 |
| 38 | Proton pump inhibitors affect the gut microbiome | Gut | 2016 | 885 |
| 39 | Causal relationships among the gut microbiome, short-chain fatty acids and metabolic diseases | Nature Genetics | 2019 | 854 |
| 40 | Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects | Nature Genetics | 2017 | 838 |
| 41 | Metabolic and cardiovascular adverse effects associated with antipsychotic drugs | Nature Reviews Endocrinology | 2012 | 832 |
| 42 | Gut microbial metabolites in obesity, NAFLD and T2DM | Nature Reviews Endocrinology | 2019 | 817 |
| 43 | Dietary factors and low-grade inflammation in relation to overweight and obesity | British Journal of Nutrition | 2011 | 816 |
| 44 | European Respiratory Society guidelines for the management of adult bronchiectasis | European Respiratory Journal | 2017 | 788 |
| 45 | Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer | Nature Medicine | 2019 | 773 |
| 46 | Definition and recommendations for advance care planning: an international consensus supported by the European Association for Palliative Care | Lancet Oncology, The | 2017 | 765 |
| 47 | Proposal for a revised definition of dilated cardiomyopathy, hypokinetic non-dilated cardiomyopathy, and its implications for clinical practice: a position statement of the ESC working group on myocardial and pericardial diseases | European Heart Journal | 2016 | 757 |
| 48 | ECCO Guidelines on Therapeutics in Crohn's Disease: Medical Treatment | Journal of Crohn's and Colitis | 2020 | 741 |
| 49 | Schizophrenia | Nature Reviews Disease Primers | 2015 | 724 |
| 50 | Efficacy and safety of fondaparinux for the prevention of venous thromboembolism in older acute medical patients: randomised placebo controlled trial | BMJ: British Medical Journal | 2006 | 723 |
