| # | Title | Journal | Year | Citations |
|---|
| 1 | The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance | Nature Medicine | 2011 | 2,120 |
| 2 | Adipose-Derived Stem Cells for Regenerative Medicine | Circulation Research | 2007 | 2,054 |
| 3 | Comparison of Weight-Loss Diets with Different Compositions of Fat, Protein, and Carbohydrates | New England Journal of Medicine | 2009 | 1,680 |
| 4 | Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix | Cell Stem Cell | 2009 | 1,669 |
| 5 | Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice | Diabetes | 2009 | 1,630 |
| 6 | Stromal cells from the adipose tissue-derived stromal vascular fraction and culture expanded adipose tissue-derived stromal/stem cells: a joint statement of the International Federation for Adipose Therapeutics and Science (IFATS) and the International Society for Cellular Therapy (ISCT) | Cytotherapy | 2013 | 1,469 |
| 7 | Metformin improves healthspan and lifespan in mice | Nature Communications | 2013 | 1,118 |
| 8 | Resveratrol Delays Age-Related Deterioration and Mimics Transcriptional Aspects of Dietary Restriction without Extending Life Span | Cell Metabolism | 2008 | 1,060 |
| 9 | Trends over 5 Decades in U.S. Occupation-Related Physical Activity and Their Associations with Obesity | PLoS ONE | 2011 | 927 |
| 10 | How Do We Define Cure of Diabetes? | Diabetes Care | 2009 | 852 |
| 11 | Association of Bariatric Surgery With Long-term Remission of Type 2 Diabetes and With Microvascular and Macrovascular Complications | JAMA - Journal of the American Medical Association | 2014 | 849 |
| 12 | Effects of COVID‐19 Lockdown on Lifestyle Behaviors in Children with Obesity Living in Verona, Italy: A Longitudinal Study | Obesity | 2020 | 769 |
| 13 | Effect of naltrexone plus bupropion on weight loss in overweight and obese adults (COR-I): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2010 | 765 |
| 14 | Effects of Aerobic and Resistance Training on Hemoglobin A1cLevels in Patients With Type 2 Diabetes | JAMA - Journal of the American Medical Association | 2010 | 727 |
| 15 | Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA | Nature | 2008 | 685 |
| 16 | Leisure-Time Running Reduces All-Cause and Cardiovascular Mortality Risk | Journal of the American College of Cardiology | 2014 | 611 |
| 17 | Effects of Different Doses of Physical Activity on Cardiorespiratory Fitness Among Sedentary, Overweight or Obese Postmenopausal Women With Elevated Blood Pressure | JAMA - Journal of the American Medical Association | 2007 | 594 |
| 18 | Ten Putative Contributors to the Obesity Epidemic | Critical Reviews in Food Science and Nutrition | 2009 | 576 |
| 19 | The Brain, Appetite, and Obesity | Annual Review of Psychology | 2008 | 546 |
| 20 | Mechanisms of insulin resistance in obesity | Frontiers of Medicine | 2013 | 518 |
| 21 | Putative contributors to the secular increase in obesity: exploring the roads less traveled | International Journal of Obesity | 2006 | 515 |
| 22 | Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ | Nature Structural and Molecular Biology | 2007 | 508 |
| 23 | Obesity and Cardiovascular Diseases | Journal of the American College of Cardiology | 2014 | 507 |
| 24 | Cognitive impairment following high fat diet consumption is associated with brain inflammation | Journal of Neuroimmunology | 2010 | 502 |
| 25 | 3 years of liraglutide versus placebo for type 2 diabetes risk reduction and weight management in individuals with prediabetes: a randomised, double-blind trial | Lancet, The | 2017 | 502 |
| 26 | Canonical Nlrp3 Inflammasome Links Systemic Low-Grade Inflammation to Functional Decline in Aging | Cell Metabolism | 2013 | 494 |
| 27 | Interventions to Slow Aging in Humans: Are We Ready? | Aging Cell | 2015 | 481 |
| 28 | Playing with bone and fat | Journal of Cellular Biochemistry | 2006 | 471 |
| 29 | Joint international consensus statement for ending stigma of obesity | Nature Medicine | 2020 | 468 |
| 30 | Emerging role of adipose tissue hypoxia in obesity and insulin resistance | International Journal of Obesity | 2009 | 446 |
| 31 | Clonal analysis of the differentiation potential of human adipose-derived adult stem cells | Journal of Cellular Physiology | 2006 | 434 |
| 32 | Endocrine and Nutritional Management of the Post-Bariatric Surgery Patient: An Endocrine Society Clinical Practice Guideline | Journal of Clinical Endocrinology and Metabolism | 2010 | 434 |
| 33 | BRAINSTEM CIRCUITS REGULATING GASTRIC FUNCTION | Annual Review of Physiology | 2006 | 426 |
| 34 | Obese-type Gut Microbiota Induce Neurobehavioral Changes in the Absence of Obesity | Biological Psychiatry | 2015 | 421 |
| 35 | Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity | JAMA - Journal of the American Medical Association | 2021 | 413 |
| 36 | Sarcopenia: A Time for Action. An SCWD Position Paper | Journal of Cachexia, Sarcopenia and Muscle | 2019 | 410 |
| 37 | Metabolic and hedonic drives in the neural control of appetite: who is the boss? | Current Opinion in Neurobiology | 2011 | 388 |
| 38 | Immunological complications of obesity | Nature Immunology | 2012 | 382 |
| 39 | Obesity Increases the Production of Proinflammatory Mediators from Adipose Tissue T Cells and Compromises TCR Repertoire Diversity: Implications for Systemic Inflammation and Insulin Resistance | Journal of Immunology | 2010 | 381 |
| 40 | Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism | Cell Metabolism | 2008 | 369 |
| 41 | Effects of Naltrexone Sustained- Release/Bupropion Sustained-Release Combination Therapy on Body Weight and Glycemic Parameters in Overweight and Obese Patients With Type 2 Diabetes | Diabetes Care | 2013 | 354 |
| 42 | Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food Intake | Neuron | 2006 | 345 |
| 43 | Berberine improves glucose metabolism through induction of glycolysis | American Journal of Physiology - Endocrinology and Metabolism | 2008 | 336 |
| 44 | Bioactives in Blueberries Improve Insulin Sensitivity in Obese, Insulin-Resistant Men and Women1–4 | Journal of Nutrition | 2010 | 331 |
| 45 | Elevated stearoyl-CoA desaturase-1 expression in skeletal muscle contributes to abnormal fatty acid partitioning in obese humans | Cell Metabolism | 2005 | 326 |
| 46 | Structure, production and signaling of leptin | Metabolism: Clinical and Experimental | 2015 | 307 |
| 47 | Ribosomal Protein S3: A KH Domain Subunit in NF-κB Complexes that Mediates Selective Gene Regulation | Cell | 2007 | 305 |
| 48 | Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes | JAMA - Journal of the American Medical Association | 2022 | 293 |
| 49 | Physiological adaptations to weight loss and factors favouring weight regain | International Journal of Obesity | 2015 | 292 |
| 50 | Transcriptional Regulation of Adipogenesis | | 2017 | 292 |
