| # | Title | Journal | Year | Citations |
|---|
| 1 | Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study | Lancet Oncology, The | 2015 | 1,031 |
| 2 | Global guideline for the diagnosis and management of mucormycosis: an initiative of the European Confederation of Medical Mycology in cooperation with the Mycoses Study Group Education and Research Consortium | Lancet Infectious Diseases, The | 2019 | 970 |
| 3 | Cholangiocarcinoma: current knowledge and future perspectives consensus statement from the European Network for the Study of Cholangiocarcinoma (ENS-CCA) | Nature Reviews Gastroenterology and Hepatology | 2016 | 964 |
| 4 | Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline | Clinical Microbiology and Infection | 2018 | 942 |
| 5 | Classification of primary and incisional abdominal wall hernias | Hernia: the Journal of Hernias and Abdominal Wall Surgery | 2009 | 915 |
| 6 | Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study | Lancet, The | 2003 | 822 |
| 7 | Letermovir Prophylaxis for Cytomegalovirus in Hematopoietic-Cell Transplantation | New England Journal of Medicine | 2017 | 796 |
| 8 | EUROASPIRE IV: A European Society of Cardiology survey on the lifestyle, risk factor and therapeutic management of coronary patients from 24 European countries | European Journal of Preventive Cardiology | 2016 | 772 |
| 9 | Panobinostat plus bortezomib and dexamethasone versus placebo plus bortezomib and dexamethasone in patients with relapsed or relapsed and refractory multiple myeloma: a multicentre, randomised, double-blind phase 3 trial | Lancet Oncology, The | 2014 | 695 |
| 10 | Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management | European Respiratory Journal | 2016 | 654 |
| 11 | Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology | Nature Genetics | 2021 | 629 |
| 12 | The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways | Blood | 2012 | 623 |
| 13 | 5-year results of accelerated partial breast irradiation using sole interstitial multicatheter brachytherapy versus whole-breast irradiation with boost after breast-conserving surgery for low-risk invasive and in-situ carcinoma of the female breast: a randomised, phase 3, non-inferiority trial | Lancet, The | 2016 | 578 |
| 14 | Single-Cell RNA-Seq Reveals the Transcriptional Landscape and Heterogeneity of Aortic Macrophages in Murine Atherosclerosis | Circulation Research | 2018 | 577 |
| 15 | Blinatumomab for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukemia | Blood | 2018 | 566 |
| 16 | Lifestyle and impact on cardiovascular risk factor control in coronary patients across 27 countries: Results from the European Society of Cardiology ESC-EORP EUROASPIRE V registry | European Journal of Preventive Cardiology | 2019 | 558 |
| 17 | Cutaneous, gastrointestinal, hepatic, endocrine, and renal side-effects of anti-PD-1 therapy | European Journal of Cancer | 2016 | 546 |
| 18 | Belantamab mafodotin for relapsed or refractory multiple myeloma (DREAMM-2): a two-arm, randomised, open-label, phase 2 study | Lancet Oncology, The | 2020 | 544 |
| 19 | Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma | Nature Medicine | 2019 | 541 |
| 20 | Biofabrication: reappraising the definition of an evolving field | Biofabrication | 2016 | 523 |
| 21 | Multiple myeloma | Lancet, The | 2015 | 511 |
| 22 | Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis | Nature Genetics | 2016 | 494 |
| 23 | 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation | Europace | 2021 | 494 |
| 24 | Neurological, respiratory, musculoskeletal, cardiac and ocular side-effects of anti-PD-1 therapy | European Journal of Cancer | 2016 | 490 |
| 25 | Efficacy of stapler versus hand-sewn closure after distal pancreatectomy (DISPACT): a randomised, controlled multicentre trial | Lancet, The | 2011 | 485 |
| 26 | Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma | Cancer Cell | 2016 | 482 |
| 27 | Peripheral neuropathic pain: a mechanism-related organizing principle based on sensory profiles | Pain | 2017 | 462 |
| 28 | Somatic mutations in ATP1A1 and ATP2B3 lead to aldosterone-producing adenomas and secondary hypertension | Nature Genetics | 2013 | 460 |
| 29 | Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors | Nature Genetics | 2018 | 438 |
| 30 | Synthetic lethal metabolic targeting of cellular senescence in cancer therapy | Nature | 2013 | 437 |
| 31 | Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell–engaging CD19/CD3-bispecific BiTE antibody blinatumomab | Blood | 2012 | 410 |
| 32 | Adoptive transfer of pp65-specific T cells for the treatment of chemorefractory cytomegalovirus disease or reactivation after haploidentical and matched unrelated stem cell transplantation | Blood | 2010 | 409 |
| 33 | CKD Prevalence Varies across the European General Population | Journal of the American Society of Nephrology: JASN | 2016 | 406 |
| 34 | Role of 18F-FDG PET/CT in the diagnosis and management of multiple myeloma and other plasma cell disorders: a consensus statement by the International Myeloma Working Group | Lancet Oncology, The | 2017 | 394 |
| 35 | Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML) | Leukemia | 2012 | 383 |
| 36 | ESCMID and ECMM joint guidelines on diagnosis and management of hyalohyphomycosis: Fusarium spp., Scedosporium spp. and others | Clinical Microbiology and Infection | 2014 | 383 |
| 37 | Autologous Stem-Cell Transplantation As First-Line Therapy in Peripheral T-Cell Lymphomas: Results of a Prospective Multicenter Study | Journal of Clinical Oncology | 2009 | 380 |
| 38 | Atlas of the Immune Cell Repertoire in Mouse Atherosclerosis Defined by Single-Cell RNA-Sequencing and Mass Cytometry | Circulation Research | 2018 | 377 |
| 39 | The Residual Risk Reduction Initiative: A Call to Action to Reduce Residual Vascular Risk in Patients with Dyslipidemia | American Journal of Cardiology | 2008 | 371 |
| 40 | Allogeneic stem cell transplantation after reduced-intensity conditioning in patients with myelofibrosis: a prospective, multicenter study of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation | Blood | 2009 | 366 |
| 41 | Improvement of Cardiac Function During Enzyme Replacement Therapy in Patients With Fabry Disease | Circulation | 2003 | 363 |
| 42 | Source localization (LORETA) of the error-related-negativity (ERN/Ne) and positivity (Pe) | Cognitive Brain Research | 2004 | 353 |
| 43 | Impella Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock | Circulation | 2019 | 353 |
| 44 | Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome–Positive B-Precursor Acute Lymphoblastic Leukemia Following Treatment With Blinatumomab: Results From a Phase II, Single-Arm, Multicenter Study | Journal of Clinical Oncology | 2017 | 348 |
| 45 | Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial | Lancet Oncology, The | 2015 | 347 |
| 46 | Pathophysiology of Heart Failure | | 2015 | 335 |
| 47 | The tyrosine kinase inhibitor dasatinib acts as a pharmacologic on/off switch for CAR T cells | Science Translational Medicine | 2019 | 326 |
| 48 | Multiple myeloma: EHA-ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up† | Annals of Oncology | 2021 | 316 |
| 49 | Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses | Annals of Neurology | 2016 | 315 |
| 50 | KTE-X19 for relapsed or refractory adult B-cell acute lymphoblastic leukaemia: phase 2 results of the single-arm, open-label, multicentre ZUMA-3 study | Lancet, The | 2021 | 315 |
