| # | Title | Journal | Year | Citations |
|---|
| 1 | 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure | European Heart Journal | 2021 | 5,558 |
| 2 | International Autoimmune Hepatitis Group Report: review of criteria for diagnosis of autoimmune hepatitis | Journal of Hepatology | 1999 | 2,681 |
| 3 | The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society | Urology | 2003 | 2,597 |
| 4 | Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study | Lancet Oncology, The | 2009 | 2,404 |
| 5 | Book: Crossing the Quality Chasm: A New Health System for the 21st Century | BMJ: British Medical Journal | 2001 | 2,403 |
| 6 | Development of a fatigue scale | Journal of Psychosomatic Research | 1993 | 2,320 |
| 7 | Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis | Gastroenterology | 2013 | 2,211 |
| 8 | Non-motor symptoms of Parkinson's disease: diagnosis and management | Lancet Neurology, The | 2006 | 2,202 |
| 9 | Consensus statement on the pathology of IgG4-related disease | Modern Pathology | 2012 | 2,171 |
| 10 | Oral Apixaban for the Treatment of Acute Venous Thromboembolism | New England Journal of Medicine | 2013 | 1,915 |
| 11 | Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial | Lancet Oncology, The | 2018 | 1,816 |
| 12 | Simplified criteria for the diagnosis of autoimmune hepatitis | Hepatology | 2008 | 1,553 |
| 13 | Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): a multinational cross-sectional study | Lancet, The | 2008 | 1,258 |
| 14 | Non-motor features of Parkinson disease | Nature Reviews Neuroscience | 2017 | 1,182 |
| 15 | Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study | Lancet Infectious Diseases, The | 2010 | 1,107 |
| 16 | Adaptive deep brain stimulation in advanced Parkinson disease | Annals of Neurology | 2013 | 1,046 |
| 17 | Diabetes in identical twins | Diabetologia | 1981 | 993 |
| 18 | The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis.. | British Journal of Dermatology | 1994 | 990 |
| 19 | Guidelines for the management of thyroid cancer | Clinical Endocrinology | 2014 | 961 |
| 20 | Progesterone and the Risk of Preterm Birth among Women with a Short Cervix | New England Journal of Medicine | 2007 | 960 |
| 21 | Iron deficiency anaemia | Lancet, The | 2016 | 960 |
| 22 | A six-item short-form survey for measuring headache impact: the HIT-6 | Quality of Life Research | 2003 | 954 |
| 23 | HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin | Nature Genetics | 2009 | 950 |
| 24 | A new questionnaire to assess the quality of life of urinary incontinent women | BJOG: an International Journal of Obstetrics and Gynaecology | 1997 | 944 |
| 25 | Beneficial effects of long-term intravenous iron therapy with ferric carboxymaltose in patients with symptomatic heart failure and iron deficiency | European Heart Journal | 2015 | 902 |
| 26 | Prevention of falls in the elderly trial (PROFET): a randomised controlled trial | Lancet, The | 1999 | 891 |
| 27 | Acute liver failure | Lancet, The | 2010 | 883 |
| 28 | The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings | Brain | 2020 | 880 |
| 29 | International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: The NMSQuest study | Movement Disorders | 2006 | 865 |
| 30 | The metric properties of a novel non‐motor symptoms scale for Parkinson's disease: Results from an international pilot study | Movement Disorders | 2007 | 838 |
| 31 | The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation | British Journal of Dermatology | 1994 | 804 |
| 32 | A randomized trial of normothermic preservation in liver transplantation | Nature | 2018 | 804 |
| 33 | Efficacy and Safety of Valganciclovir vs. Oral Ganciclovir for Prevention of Cytomegalovirus Disease in Solid Organ Transplant Recipients | American Journal of Transplantation | 2004 | 792 |
| 34 | Measurement of twitch transdiaphragmatic, esophageal, and endotracheal tube pressure with bilateral anterolateral magnetic phrenic nerve stimulation in patients in the intensive care unit | Critical Care Medicine | 2001 | 790 |
| 35 | Guidelines for the diagnosis and management of individuals with neurofibromatosis 1 | Journal of Medical Genetics | 2006 | 778 |
| 36 | Prediction of outcome in individuals with diabetic foot ulcers: focus on the differences between individuals with and without peripheral arterial disease. The EURODIALE Study | Diabetologia | 2008 | 762 |
| 37 | Development and validation of a prognostic score to predict mortality in patients with acute-on-chronic liver failure | Journal of Hepatology | 2014 | 741 |
| 38 | Global Vascular Guidelines on the Management of Chronic Limb-Threatening Ischemia | European Journal of Vascular and Endovascular Surgery | 2019 | 741 |
| 39 | Evolution of indications and results of liver transplantation in Europe. A report from the European Liver Transplant Registry (ELTR) | Journal of Hepatology | 2012 | 734 |
| 40 | Recommendations for interpretation of 12-lead electrocardiogram in the athlete | European Heart Journal | 2010 | 730 |
| 41 | Diagnosis and phenotypic classification of Wilson disease1 | Liver International | 2003 | 726 |
| 42 | Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma | Cancer Cell | 2017 | 716 |
| 43 | Pomalidomide plus low-dose dexamethasone versus high-dose dexamethasone alone for patients with relapsed and refractory multiple myeloma (MM-003): a randomised, open-label, phase 3 trial | Lancet Oncology, The | 2013 | 710 |
| 44 | Efficacy and safety of leflunomide compared with placebo and sulphasalazine in active rheumatoid arthritis: a double-blind, randomised, multicentre trial | Lancet, The | 1999 | 706 |
| 45 | An Entirely Subcutaneous Implantable Cardioverter–Defibrillator | New England Journal of Medicine | 2010 | 686 |
| 46 | Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013 | Journal of Hepatology | 2014 | 685 |
| 47 | Guidelines for the diagnosis and treatment of cholangiocarcinoma: an update | Gut | 2012 | 678 |
| 48 | Anatomic and Disease Specificity of NADH CoQ1Reductase (Complex I) Deficiency in Parkinson's Disease | Journal of Neurochemistry | 1990 | 670 |
| 49 | How to select outcome measurement instruments for outcomes included in a “Core Outcome Set” – a practical guideline | Trials | 2016 | 659 |
| 50 | EFSUMB Guidelines and Recommendations on the Clinical Use of Liver Ultrasound Elastography, Update 2017 (Long Version) | Ultraschall in Der Medizin | 2017 | 659 |
