| # | Title | Journal | Year | Citations |
|---|
| 1 | Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines | Journal of Extracellular Vesicles | 2018 | 6,961 |
| 2 | Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection | New England Journal of Medicine | 2002 | 6,268 |
| 3 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 4 | Biological properties of extracellular vesicles and their physiological functions | Journal of Extracellular Vesicles | 2015 | 3,973 |
| 5 | Identification and expansion of human colon-cancer-initiating cells | Nature | 2007 | 3,690 |
| 6 | Guidelines for the use and interpretation of assays for monitoring autophagy | Autophagy | 2012 | 3,122 |
| 7 | Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease: Consensus Statement of the European Atherosclerosis Society | European Heart Journal | 2013 | 2,132 |
| 8 | Criteria for Defining Polycystic Ovary Syndrome as a Predominantly Hyperandrogenic Syndrome: An Androgen Excess Society Guideline | Journal of Clinical Endocrinology and Metabolism | 2006 | 1,811 |
| 9 | The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report | Fertility and Sterility | 2009 | 1,639 |
| 10 | Wnt activity defines colon cancer stem cells and is regulated by the microenvironment | Nature Cell Biology | 2010 | 1,623 |
| 11 | Consensus on women’s health aspects of polycystic ovary syndrome (PCOS): the Amsterdam ESHRE/ASRM-Sponsored 3rd PCOS Consensus Workshop Group | Fertility and Sterility | 2012 | 1,494 |
| 12 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 13 | An assessment of the global impact of 21st century land use change on soil erosion | Nature Communications | 2017 | 1,398 |
| 14 | Single and Coupled Electrochemical Processes and Reactors for the Abatement of Organic Water Pollutants: A Critical Review | Chemical Reviews | 2015 | 1,273 |
| 15 | Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells | Nature | 2010 | 1,235 |
| 16 | Modeling NAFLD disease burden in China, France, Germany, Italy, Japan, Spain, United Kingdom, and United States for the period 2016–2030 | Journal of Hepatology | 2018 | 1,157 |
| 17 | Asthmatic bronchial epithelial cells have a deficient innate immune response to infection with rhinovirus | Journal of Experimental Medicine | 2005 | 1,105 |
| 18 | Exome Sequencing Reveals VCP Mutations as a Cause of Familial ALS | Neuron | 2010 | 1,100 |
| 19 | Breast Cancer Cell Lines Contain Functional Cancer Stem Cells with Metastatic Capacity and a Distinct Molecular Signature | Cancer Research | 2009 | 1,067 |
| 20 | Visceral Adiposity Index | Diabetes Care | 2010 | 1,062 |
| 21 | The Genome of the Sea Urchin Strongylocentrotus purpuratus | Science | 2006 | 1,018 |
| 22 | Polycystic ovary syndrome | Nature Reviews Disease Primers | 2016 | 1,004 |
| 23 | Colon Cancer Stem Cells Dictate Tumor Growth and Resist Cell Death by Production of Interleukin-4 | Cell Stem Cell | 2007 | 968 |
| 24 | Haploinsufficiency of ATP1A2 encoding the Na+/K+ pump α2 subunit associated with familial hemiplegic migraine type 2 | Nature Genetics | 2003 | 884 |
| 25 | Oxygen isotopes in mammal bone phosphate: A new tool for paleohydrological and paleoclimatological research? | Geochimica Et Cosmochimica Acta | 1984 | 874 |
| 26 | Citrus flavonoids: Molecular structure, biological activity and nutritional properties: A review | Food Chemistry | 2007 | 873 |
| 27 | Asymmetric Single Point Incremental Forming of Sheet Metal | CIRP Annals - Manufacturing Technology | 2005 | 872 |
| 28 | Severe plastic deformation (SPD) processes for metals | CIRP Annals - Manufacturing Technology | 2008 | 830 |
| 29 | Second European evidence-based consensus on the prevention, diagnosis and management of opportunistic infections in inflammatory bowel disease | Journal of Crohn's and Colitis | 2014 | 804 |
| 30 | Quantifying submarine groundwater discharge in the coastal zone via multiple methods | Science of the Total Environment | 2006 | 791 |
| 31 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 32 | Efficacy and safety of sorafenib in patients with advanced hepatocellular carcinoma: Subanalyses of a phase III trial | Journal of Hepatology | 2012 | 736 |
| 33 | Fixed point theorems for -contractive type mappings | Nonlinear Analysis: Theory, Methods & Applications | 2012 | 716 |
| 34 | Intelligent Management Systems for Energy Efficiency in Buildings | ACM Computing Surveys | 2014 | 697 |
| 35 | Performance modeling of epidemic routing | Computer Networks | 2007 | 657 |
| 36 | Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity | Proceedings of the National Academy of Sciences of the United States of America | 2008 | 654 |
| 37 | Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment | European Heart Journal | 2015 | 644 |
| 38 | A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan | Cell Metabolism | 2015 | 635 |
| 39 | The chemistry of melatonin's interaction with reactive species | Journal of Pineal Research | 2003 | 630 |
| 40 | CD44v6 Is a Marker of Constitutive and Reprogrammed Cancer Stem Cells Driving Colon Cancer Metastasis | Cell Stem Cell | 2014 | 617 |
| 41 | Photocatalysis: a promising route for 21st century organic chemistry | Chemical Communications | 2007 | 613 |
| 42 | The superior effect of nature based solutions in land management for enhancing ecosystem services | Science of the Total Environment | 2018 | 606 |
| 43 | Enoxaparin Prevents Portal Vein Thrombosis and Liver Decompensation in Patients With Advanced Cirrhosis | Gastroenterology | 2012 | 604 |
| 44 | Oxidative stress preconditioning of mouse perivascular myogenic progenitors selects a subpopulation of cells with a distinct survival advantage in vitro and in vivo | Cell Death and Disease | 2018 | 600 |
| 45 | Cancer stem cell definitions and terminology: the devil is in the details | Nature Reviews Cancer | 2012 | 599 |
| 46 | Sustained virological response to interferon-α is associated with improved outcome in HCV-related cirrhosis: A retrospective study | Hepatology | 2007 | 585 |
| 47 | Advanced methods of plant disease detection. A review | Agronomy for Sustainable Development | 2015 | 579 |
| 48 | On-chip generation of high-dimensional entangled quantum states and their coherent control | Nature | 2017 | 574 |
| 49 | Myeloid sarcoma: clinico-pathologic, phenotypic and cytogenetic analysis of 92 adult patients | Leukemia | 2007 | 571 |
| 50 | The impact of physical activity on psychological health during Covid-19 pandemic in Italy | Heliyon | 2020 | 568 |
