| # | Title | Journal | Year | Citations |
|---|
| 1 | Proposals for the Classification of the Acute Leukaemias French‐American‐British (FAB) Co‐operative Group | British Journal of Haematology | 1976 | 5,316 |
| 2 | Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel | Blood | 2017 | 4,375 |
| 3 | A comprehensive genetic map of the human genome based on 5,264 microsatellites | Nature | 1996 | 2,916 |
| 4 | Proposals for the classification of the myelodysplastic syndromes | British Journal of Haematology | 1982 | 2,230 |
| 5 | Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease [see comments] | Blood | 1995 | 2,025 |
| 6 | Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling | New England Journal of Medicine | 1989 | 1,916 |
| 7 | Inborn errors of type I IFN immunity in patients with life-threatening COVID-19 | Science | 2020 | 1,749 |
| 8 | On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection | New England Journal of Medicine | 2015 | 1,302 |
| 9 | The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus | Nature | 1990 | 1,298 |
| 10 | Outcome of Cord-Blood Transplantation from Related and Unrelated Donors | New England Journal of Medicine | 1997 | 1,255 |
| 11 | Mutations in the hepatocyte nuclear factor-1α gene in maturity-onset diabetes of the young (MODY3) | Nature | 1996 | 1,240 |
| 12 | Long-term outcome of patients in the LNH-98.5 trial, the first randomized study comparing rituximab-CHOP to standard CHOP chemotherapy in DLBCL patients: a study by the Groupe d'Etudes des Lymphomes de l'Adulte | Blood | 2010 | 1,193 |
| 13 | All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments] | Blood | 1990 | 1,185 |
| 14 | Definition of organ involvement and treatment response in immunoglobulin light chain amyloidosis (AL): A consensus opinion from the 10th International Symposium on Amyloid and Amyloidosis | American Journal of Hematology | 2005 | 1,179 |
| 15 | Transfusion independence and HMGA2 activation after gene therapy of human β-thalassaemia | Nature | 2010 | 1,153 |
| 16 | Prolonged Survival in Stage III Melanoma with Ipilimumab Adjuvant Therapy | New England Journal of Medicine | 2016 | 1,140 |
| 17 | Targeting of CD44 eradicates human acute myeloid leukemic stem cells | Nature Medicine | 2006 | 1,127 |
| 18 | Nucleotide sequence of the hepatitis B virus genome (subtype ayw) cloned in E. coli | Nature | 1979 | 1,070 |
| 19 | Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease | Blood | 1995 | 1,061 |
| 20 | Transplants of Umbilical-Cord Blood or Bone Marrow from Unrelated Donors in Adults with Acute Leukemia | New England Journal of Medicine | 2004 | 1,058 |
| 21 | Myoblast transplantation for heart failure | Lancet, The | 2001 | 1,044 |
| 22 | Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database | Annals of the Rheumatic Diseases | 2010 | 1,017 |
| 23 | Rituximab maintenance for 2 years in patients with high tumour burden follicular lymphoma responding to rituximab plus chemotherapy (PRIMA): a phase 3, randomised controlled trial | Lancet, The | 2011 | 957 |
| 24 | EULAR/ERA-EDTA recommendations for the management of ANCA-associated vasculitis | Annals of the Rheumatic Diseases | 2016 | 940 |
| 25 | A Review of Activity Indices and Efficacy End Points for Clinical Trials of Medical Therapy in Adults With Ulcerative Colitis | Gastroenterology | 2007 | 917 |
| 26 | Human Inborn Errors of Immunity: 2019 Update on the Classification from the International Union of Immunological Societies Expert Committee | Journal of Clinical Immunology | 2020 | 881 |
| 27 | Subcutaneous versus intravenous administration of bortezomib in patients with relapsed multiple myeloma: a randomised, phase 3, non-inferiority study | Lancet Oncology, The | 2011 | 835 |
| 28 | International Consensus Classification of Myeloid Neoplasms and Acute Leukemias: integrating morphologic, clinical, and genomic data | Blood | 2022 | 814 |
| 29 | Diagnosis and management of AML in adults: 2022 recommendations from an international expert panel on behalf of the ELN | Blood | 2022 | 805 |
| 30 | TET2 Inactivation Results in Pleiotropic Hematopoietic Abnormalities in Mouse and Is a Recurrent Event during Human Lymphomagenesis | Cancer Cell | 2011 | 792 |
| 31 | International Union of Immunological Societies: 2017 Primary Immunodeficiency Diseases Committee Report on Inborn Errors of Immunity | Journal of Clinical Immunology | 2018 | 732 |
| 32 | The EUROclass trial: defining subgroups in common variable immunodeficiency | Blood | 2008 | 722 |
| 33 | Clinical, biological, and endoscopic picture of attacks of Crohn's disease | Gastroenterology | 1990 | 698 |
| 34 | Preexisting Donor-Specific HLA Antibodies Predict Outcome in Kidney Transplantation | Journal of the American Society of Nephrology: JASN | 2010 | 689 |
| 35 | Bortezomib, thalidomide, and dexamethasone with or without daratumumab before and after autologous stem-cell transplantation for newly diagnosed multiple myeloma (CASSIOPEIA): a randomised, open-label, phase 3 study | Lancet, The | 2019 | 665 |
| 36 | Close linkage of glucokinase locus on chromosome 7p to early-onset non-insulin-dependent diabetes mellitus | Nature | 1992 | 637 |
| 37 | Nonsense mutation in the glucokinase gene causes early-onset non-insulin-dependent diabetes mellitus | Nature | 1992 | 636 |
| 38 | TRIM family proteins: retroviral restriction and antiviral defence | Nature Reviews Microbiology | 2005 | 628 |
| 39 | Primary Immunodeficiency Diseases: an Update on the Classification from the International Union of Immunological Societies Expert Committee for Primary Immunodeficiency 2015 | Journal of Clinical Immunology | 2015 | 621 |
| 40 | The Logistic Organ Dysfunction system. A new way to assess organ dysfunction in the intensive care unit. ICU Scoring Group | JAMA - Journal of the American Medical Association | 1996 | 613 |
| 41 | Risk assessment for patients with chronic myeloid leukaemia before allogeneic blood or marrow transplantation | Lancet, The | 1998 | 609 |
| 42 | Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: An international consensus | Journal of the American Academy of Dermatology | 2007 | 597 |
| 43 | Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy | Gastroenterology | 2000 | 594 |
| 44 | Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial | Lancet Oncology, The | 2013 | 586 |
| 45 | Identification of Novel TGF-β/Smad Gene Targets in Dermal Fibroblasts using a Combined cDNA Microarray/Promoter Transactivation Approach | Journal of Biological Chemistry | 2001 | 575 |
| 46 | Maintenance of Remission Among Patients With Crohn's Disease on Antimetabolite Therapy After Infliximab Therapy Is Stopped | Gastroenterology | 2012 | 558 |
| 47 | Transforming Growth Factor-β Signaling Through the Smad Pathway: Role in Extracellular Matrix Gene Expression and Regulation | Journal of Investigative Dermatology | 2002 | 550 |
| 48 | Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials | Lancet Oncology, The | 2014 | 549 |
| 49 | A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial | Lancet, The | 2007 | 547 |
| 50 | The gene expression profile of nodal peripheral T-cell lymphoma demonstrates a molecular link between angioimmunoblastic T-cell lymphoma (AITL) and follicular helper T (TFH) cells | Blood | 2007 | 533 |
