| # | Title | Journal | Year | Citations |
|---|
| 1 | Tissue microarrays for high-throughput molecular profiling of tumor specimens | Nature Medicine | 1998 | 3,661 |
| 2 | Mechanisms of Neuroprotective Action of Vitamin D3 | Biochemistry (Moscow) | 2004 | 3,514 |
| 3 | Cumulated gain-based evaluation of IR techniques | ACM Transactions on Information Systems | 2002 | 3,084 |
| 4 | Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index | Nature Genetics | 2010 | 2,634 |
| 5 | Strong Association of De Novo Copy Number Mutations with Autism | Science | 2007 | 2,497 |
| 6 | Premature ageing in mice expressing defective mitochondrial DNA polymerase | Nature | 2004 | 2,318 |
| 7 | Synaptic, transcriptional and chromatin genes disrupted in autism | Nature | 2014 | 2,254 |
| 8 | Does Gamification Work? -- A Literature Review of Empirical Studies on Gamification | Nature | 2014 | 2,119 |
| 9 | Diagnostic Assessment of Deep Learning Algorithms for Detection of Lymph Node Metastases in Women With Breast Cancer | JAMA - Journal of the American Medical Association | 2017 | 2,003 |
| 10 | Promoting ecosystem and human health in urban areas using Green Infrastructure: A literature review | Landscape and Urban Planning | 2007 | 1,872 |
| 11 | Defining the role of common variation in the genomic and biological architecture of adult human height | Nature Genetics | 2014 | 1,818 |
| 12 | What is self-rated health and why does it predict mortality? Towards a unified conceptual model | Social Science and Medicine | 2009 | 1,801 |
| 13 | Hundreds of variants clustered in genomic loci and biological pathways affect human height | Nature | 2010 | 1,789 |
| 14 | Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017 | JAMA Oncology | 2019 | 1,691 |
| 15 | Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study | Lancet, The | 2001 | 1,652 |
| 16 | Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data | BMJ: British Medical Journal | 2017 | 1,408 |
| 17 | In vivo amplification of the androgen receptor gene and progression of human prostate cancer | Nature Genetics | 1995 | 1,316 |
| 18 | The Oslo definitions for coeliac disease and related terms | Gut | 2013 | 1,300 |
| 19 | Positional cloning of the APECED gene | Nature Genetics | 1997 | 1,294 |
| 20 | Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies | BMJ: British Medical Journal | 2005 | 1,284 |
| 21 | Autoantibody against oxidised LDL and progression of carotid atherosclerosis | Lancet, The | 1992 | 1,270 |
| 22 | Screening and prostate cancer mortality: results of the European Randomised Study of Screening for Prostate Cancer (ERSPC) at 13 years of follow-up | Lancet, The | 2014 | 1,261 |
| 23 | Temporal development of the gut microbiome in early childhood from the TEDDY study | Nature | 2018 | 1,220 |
| 24 | Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors | Genes Chromosomes and Cancer | 1994 | 1,215 |
| 25 | Genome-wide association study identifies 74 loci associated with educational attainment | Nature | 2016 | 1,204 |
| 26 | Efficacy of a prophylactic adjuvanted bivalent L1 virus-like-particle vaccine against infection with human papillomavirus types 16 and 18 in young women: an interim analysis of a phase III double-blind, randomised controlled trial | Lancet, The | 2007 | 1,153 |
| 27 | Are leader stereotypes masculine? A meta-analysis of three research paradigms. | Psychological Bulletin | 2011 | 1,104 |
| 28 | Analysis of shared heritability in common disorders of the brain | Science | 2018 | 1,085 |
| 29 | The 2020 report of The Lancet Countdown on health and climate change: responding to converging crises | Lancet, The | 2021 | 1,030 |
| 30 | 1D convolutional neural networks and applications: A survey | Mechanical Systems and Signal Processing | 2021 | 1,005 |
| 31 | EAACI Food Allergy and Anaphylaxis Guidelines: diagnosis and management of food allergy | Allergy: European Journal of Allergy and Clinical Immunology | 2014 | 979 |
| 32 | Causal Mechanisms in the Social Sciences | Annual Review of Sociology | 2010 | 974 |
| 33 | Definition, structure, content, use and impacts of electronic health records: A review of the research literature | International Journal of Medical Informatics | 2008 | 948 |
| 34 | Challenging games help students learn: An empirical study on engagement, flow and immersion in game-based learning | Computers in Human Behavior | 2016 | 945 |
| 35 | Muscle Injuries | American Journal of Sports Medicine | 2005 | 905 |
| 36 | Human Estrogen Receptor β-Gene Structure, Chromosomal Localization, and Expression Pattern1 | Journal of Clinical Endocrinology and Metabolism | 1997 | 879 |
| 37 | Diagnosis and management of adult coeliac disease: guidelines from the British Society of Gastroenterology | Gut | 2014 | 870 |
| 38 | Spectrum of gluten-related disorders: consensus on new nomenclature and classification | BMC Medicine | 2012 | 855 |
| 39 | Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis | ELife | 2014 | 851 |
| 40 | Prevalence of Celiac Disease among Children in Finland | New England Journal of Medicine | 2003 | 843 |
| 41 | Probiotics: A novel approach in the management of food allergy☆☆☆★★★ | Journal of Allergy and Clinical Immunology | 1997 | 838 |
| 42 | Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution | Nature Genetics | 2010 | 836 |
| 43 | MicroRNA Expression Profiling in Prostate Cancer | Cancer Research | 2007 | 833 |
| 44 | Probiotics in the management of atopic eczema | Clinical and Experimental Allergy | 2000 | 792 |
| 45 | The rise of motivational information systems: A review of gamification research | International Journal of Information Management | 2019 | 779 |
| 46 | IR evaluation methods for retrieving highly relevant documents | International Journal of Information Management | 2000 | 766 |
| 47 | Breast-Cancer Risk in Families with Mutations in PALB2 | New England Journal of Medicine | 2014 | 745 |
| 48 | The Drosophila Toll Signaling Pathway | Journal of Immunology | 2011 | 736 |
| 49 | The EUROclass trial: defining subgroups in common variable immunodeficiency | Blood | 2008 | 722 |
| 50 | κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages">Anti-Inflammatory Effects of Flavonoids: Genistein, Kaempferol, Quercetin, and Daidzein Inhibit STAT-1 and NF-κB Activations, Whereas Flavone, Isorhamnetin, Naringenin, and Pelargonidin Inhibit only NF-κB Activation along with Their Inhibitory Effect on iNOS Expression and NO Production in Activated Macrophages | Mediators of Inflammation | 2007 | 712 |
