SIFT: Predicting amino acid changes that affect protein function | Nucleic Acids Research | 2003 | 3.7K |
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa | Science | 2003 | 1.1K |
Molecular diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup of diffuse large B cell lymphoma related to Hodgkin lymphoma | Journal of Experimental Medicine | 2003 | 869 |
The case for early detection | Nature Reviews Cancer | 2003 | 860 |
Prostate-specific deletion of the murine Pten tumor suppressor gene leads to metastatic prostate cancer | Cancer Cell | 2003 | 852 |
Controlling the double helix | Nature | 2003 | 850 |
The proliferation gene expression signature is a quantitative integrator of oncogenic events that predicts survival in mantle cell lymphoma | Cancer Cell | 2003 | 751 |
Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms | Gastroenterology | 2003 | 745 |
Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins | Nature Cell Biology | 2003 | 737 |
The role of FLT3 in haematopoietic malignancies | Nature Reviews Cancer | 2003 | 657 |
Chronic graft-versus-host disease | Biology of Blood and Marrow Transplantation | 2003 | 654 |
Voriconazole treatment for less-common, emerging, or refractory fungal infections | Clinical Infectious Diseases | 2003 | 562 |
Implementation of the Women's Health Initiative study design | Annals of Epidemiology | 2003 | 538 |
Rheb promotes cell growth as a component of the insulin/TOR signalling network | Nature Cell Biology | 2003 | 535 |
Histone sumoylation is associated with transcriptional repression | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 524 |
A common dominant TLR5 stop codon polymorphism abolishes flagellin signaling and is associated with susceptibility to legionnaires' disease | Journal of Experimental Medicine | 2003 | 513 |
Differences in breast cancer stage, treatment, and survival by race and ethnicity | Archives of Internal Medicine | 2003 | 509 |
Trans-acting regulatory variation in Saccharomyces cerevisiae and the role of transcription factors | Nature Genetics | 2003 | 505 |
Graft-versus-host disease after nonmyeloablative versus conventional hematopoietic stem cell transplantation | Blood | 2003 | 488 |
Late cytomegalovirus disease and mortality in recipients of allogeneic hematopoietic stem cell transplants: importance of viral load and T-cell immunity | Blood | 2003 | 486 |
Physical activity levels before and after a diagnosis of breast carcinoma: the Health, Eating, Activity, and Lifestyle (HEAL) study | Cancer | 2003 | 467 |
Large-scale discovery of induced point mutations with high-throughput TILLING | Genome Research | 2003 | 420 |
Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis | Proceedings of the National Academy of Sciences of the United States of America | 2003 | 411 |
Phylogenomics of the nucleosome | Nature Structural and Molecular Biology | 2003 | 409 |
Roles of PDGF in animal development | Development (Cambridge) | 2003 | 404 |