| # | Title | Journal | Year | Citations |
|---|
| 1 | Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial | Lancet, The | 2005 | 3,840 |
| 2 | Primary prevention of cardiovascular disease with atorvastatin in type 2 diabetes in the Collaborative Atorvastatin Diabetes Study (CARDS): multicentre randomised placebo-controlled trial | Lancet, The | 2004 | 3,502 |
| 3 | Preliminary criteria for the classification of Sjögren's syndrome. Results of a prospective concerted action supported by the European community | Arthritis and Rheumatism | 1993 | 1,477 |
| 4 | Autosomal dominant hypophosphataemic rickets is associated with mutations in FGF23 | Nature Genetics | 2000 | 1,411 |
| 5 | Prospective comparison of faecal incontinence grading systems | Gut | 1999 | 1,157 |
| 6 | What features improve the accuracy of clinical diagnosis in Parkinson's disease | Neurology | 1992 | 1,139 |
| 7 | What is oxidative stress? | Metabolism: Clinical and Experimental | 2000 | 1,133 |
| 8 | A gene (PEX) with homologies to endopeptidases is mutated in patients with X–linked hypophosphatemic rickets | Nature Genetics | 1995 | 1,067 |
| 9 | Andrology: Polycystic ovary syndrome: the spectrum of the disorder in 1741 patients | Human Reproduction | 1995 | 912 |
| 10 | VIRUS-LIKE PARTICLES IN SERUM OF PATIENTS WITH AUSTRALIA-ANTIGEN-ASSOCIATED HEPATITIS | Lancet, The | 1970 | 902 |
| 11 | A Clinicopathologic Study of 100 Cases of Parkinson's Disease | Archives of Neurology | 1993 | 881 |
| 12 | Observations on the Pathology of Ménière's Syndrome | Journal of Laryngology and Otology | 1938 | 846 |
| 13 | Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study | Clinical Endocrinology | 2000 | 843 |
| 14 | The “Primary” Antiphospholipid Syndrome | Medicine (United States) | 1989 | 838 |
| 15 | Randomised trial of endoscopic steriting versus surgical bypass in malignant low bileduct obstruction | Lancet, The | 1994 | 820 |
| 16 | CRICOID PRESSURE TO CONTROL REGURGITATION OF STOMACH CONTENTS DURING INDUCTION OF ANÆSTHESIA | Lancet, The | 1961 | 811 |
| 17 | POLYCYSTIC OVARIES—A COMMON FINDING IN NORMAL WOMEN | Lancet, The | 1988 | 773 |
| 18 | MULTIFOLLICULAR OVARIES: CLINICAL AND ENDOCRINE FEATURES AND RESPONSE TO PULSATILE GONADOTROPIN RELEASING HORMONE | Lancet, The | 1985 | 700 |
| 19 | The impact of microemboli during cardiopulmonary bypass on neuropsychological functioning. | Stroke | 1994 | 695 |
| 20 | A common molecular basis for three inherited kidney stone diseases | Nature | 1996 | 694 |
| 21 | Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I]-FP-CIT SPECT imaging: The [123I]-FP-CIT study group | Movement Disorders | 2000 | 650 |
| 22 | Preconditioning the human myocardium | Lancet, The | 1993 | 633 |
| 23 | INSTABILITY OF THE FOOT AFFER INJURIES TO THE LATERAL LIGAMENT OF THE ANKLE | Journal of Bone and Joint Surgery: British Volume | 1965 | 600 |
| 24 | Perioperative Plasma Volume Expansion Reduces the Incidence of Gut Mucosal Hypoperfusion During Cardiac Surgery | Archives of Surgery | 1995 | 596 |
| 25 | The Wilson disease gene: spectrum of mutations and their consequences | Nature Genetics | 1995 | 551 |
| 26 | An open study of B lymphocyte depletion in systemic lupus erythematosus | Arthritis and Rheumatism | 2002 | 539 |
| 27 | Premature ovarian failure | Human Reproduction Update | 2005 | 537 |
| 28 | A Short Clinical Diagnostic Self-rating Scale for Psychoneurotic Patients | British Journal of Psychiatry | 1966 | 528 |
| 29 | Comparison of commonly used clinical indicators of hypovolaemia with gastrointestinal tonometry | Intensive Care Medicine | 1997 | 528 |
| 30 | INHIBITION OF GASTRIN AND GASTRIC-ACID SECRETION BY GROWTH-HORMONE RELEASE-INHIBITING HORMONE | Lancet, The | 1974 | 519 |
| 31 | Synthetic strogenic Agents without the Phenanthrene Nucleus | Nature | 1936 | 499 |
| 32 | Effects of the calcimimetic cinacalcet HCl on cardiovascular disease, fracture, and health-related quality of life in secondary hyperparathyroidism | Kidney International | 2005 | 499 |
| 33 | ACROMEGALY | Clinical Endocrinology | 1987 | 498 |
| 34 | Causes of venous ulceration: a new hypothesis | BMJ: British Medical Journal | 1988 | 482 |
| 35 | Recognition of Mental State Terms | British Journal of Psychiatry | 1994 | 477 |
| 36 | Hypersecretion of luteinising hormone, infertility, and miscarriage | Lancet, The | 1990 | 475 |
| 37 | EANM/ESC procedural guidelines for myocardial perfusion imaging in nuclear cardiology | European Journal of Nuclear Medicine and Molecular Imaging | 2005 | 467 |
| 38 | Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document | Gut | 2002 | 441 |
| 39 | Outcome of ANCA-associated renal vasculitis: a 5-year retrospective study | American Journal of Kidney Diseases | 2003 | 435 |
| 40 | Tumour necrosis factor-alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine | Clinical and Experimental Immunology | 2008 | 427 |
| 41 | Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine | Annals of Neurology | 1992 | 426 |
| 42 | VASOACTIVE INTESTINAL PEPTIDE AND WATERY-DIARRHŒA SYNDROME | Lancet, The | 1973 | 424 |
| 43 | Myocardial perfusion scintigraphy: the evidence | European Journal of Nuclear Medicine and Molecular Imaging | 2004 | 424 |
| 44 | HETEROGENEITY OF THE POLYCYSTIC OVARY SYNDROME: CLINICAL, ENDOCRINE AND ULTRASOUND FEATURES IN 556 PATIENTS | Clinical Endocrinology | 1989 | 418 |
| 45 | Estimation of cerebrovascular reactivity using transcranial Doppler, including the use of breath-holding as the vasodilatory stimulus. | Stroke | 1992 | 417 |
| 46 | Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria | Journal of Vascular and Interventional Radiology | 2009 | 416 |
| 47 | A Preliminary Study of the Transmission Dynamics of the Human Immunodeficiency Virus (HIV), the Causative Agent of AIDS | Mathematical Medicine and Biology | 1986 | 414 |
| 48 | Colour Reactions on Paper Chromatograms by a Dipping Technique | Nature | 1953 | 363 |
| 49 | INDUCTION OF OVULATION FOR IN-VITRO FERTILISATION USING BUSERELIN AND GONADOTROPINS | Lancet, The | 1984 | 349 |
| 50 | The acute-phase response after bisphosphonate administration | Calcified Tissue International | 1987 | 348 |
