| # | Title | Journal | Year | Citations |
|---|
| 1 | Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) | Autophagy | 2016 | 4,701 |
| 2 | Allergic Rhinitis and its Impact on Asthma (ARIA) 2008* | Allergy: European Journal of Allergy and Clinical Immunology | 2008 | 3,827 |
| 3 | Arsenic round the world: a review | Talanta | 2002 | 2,969 |
| 4 | Regorafenib for patients with hepatocellular carcinoma who progressed on sorafenib treatment (RESORCE): a randomised, double-blind, placebo-controlled, phase 3 trial | Lancet, The | 2017 | 2,771 |
| 5 | The role of autophagy during the early neonatal starvation period | Nature | 2004 | 2,630 |
| 6 | Pembrolizumab in patients with advanced hepatocellular carcinoma previously treated with sorafenib (KEYNOTE-224): a non-randomised, open-label phase 2 trial | Lancet Oncology, The | 2018 | 1,816 |
| 7 | Electrocatalytic process of CO selectivity in electrochemical reduction of CO2 at metal electrodes in aqueous media | Electrochimica Acta | 1994 | 1,679 |
| 8 | Reconstitution of I(KATP): An Inward Rectifier Subunit Plus the Sulfonylurea Receptor | Science | 1995 | 1,658 |
| 9 | Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 update | Hepatology International | 2017 | 1,537 |
| 10 | Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 | Autophagy | 2021 | 1,430 |
| 11 | Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase | Science | 1999 | 1,403 |
| 12 | Electrochemical CO2 Reduction on Metal Electrodes | | 2008 | 1,365 |
| 13 | Pembrolizumab As Second-Line Therapy in Patients With Advanced Hepatocellular Carcinoma in KEYNOTE-240: A Randomized, Double-Blind, Phase III Trial | Journal of Clinical Oncology | 2020 | 1,255 |
| 14 | Pervasive human-driven decline of life on Earth points to the need for transformative change | Science | 2019 | 1,213 |
| 15 | Requirement for Vα14 NKT Cells in IL-12-Mediated Rejection of Tumors | Science | 1997 | 1,190 |
| 16 | PRODUCTION OF CO AND CH4IN ELECTROCHEMICAL REDUCTION OF CO2AT METAL ELECTRODES IN AQUEOUS HYDROGENCARBONATE SOLUTION | Chemistry Letters | 1985 | 1,091 |
| 17 | Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues | Oncogene | 2006 | 1,088 |
| 18 | Functional Specialization of Interleukin-17 Family Members | Immunity | 2011 | 1,088 |
| 19 | The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease | Nature Genetics | 2007 | 1,045 |
| 20 | Mesopore-Modified Zeolites: Preparation, Characterization, and Applications | Chemical Reviews | 2006 | 1,016 |
| 21 | FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro. | Journal of Antibiotics | 1987 | 1,013 |
| 22 | Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants | Biological Psychiatry | 2003 | 990 |
| 23 | Molecular mechanisms regulating NLRP3 inflammasome activation | Cellular and Molecular Immunology | 2016 | 990 |
| 24 | Morphogenesis and Renewal of Hair Follicles from Adult Multipotent Stem Cells | Cell | 2001 | 975 |
| 25 | Self-assembly of ten molecules into nanometre-sized organic host frameworks | Nature | 1995 | 940 |
| 26 | A Family of Sulfonylurea Receptors Determines the Pharmacological Properties of ATP-Sensitive K+ Channels | Neuron | 1996 | 922 |
| 27 | Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids | Plant Journal | 2014 | 911 |
| 28 | Functional genomics by integrated analysis of metabolome and transcriptome of Arabidopsis plants over-expressing an MYB transcription factor | Plant Journal | 2005 | 891 |
| 29 | Observation of High-Energy Astrophysical Neutrinos in Three Years of IceCube Data | Physical Review Letters | 2014 | 873 |
| 30 | Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the Study of the Liver (APASL) 2014 | Hepatology International | 2014 | 861 |
| 31 | Phylogeny, identification and nomenclature of the genusAspergillus | Studies in Mycology | 2014 | 835 |
| 32 | Recent progress in flapping wing aerodynamics and aeroelasticity | Progress in Aerospace Sciences | 2010 | 802 |
| 33 | Polyamines: Mysterious Modulators of Cellular Functions | Biochemical and Biophysical Research Communications | 2000 | 776 |
| 34 | Role of TBX1 in human del22q11.2 syndrome | Lancet, The | 2003 | 776 |
| 35 | BTLA is a lymphocyte inhibitory receptor with similarities to CTLA-4 and PD-1 | Nature Immunology | 2003 | 768 |
| 36 | Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition) | European Journal of Immunology | 2019 | 766 |
| 37 | Temperature response of photosynthesis in C3, C4, and CAM plants: temperature acclimation and temperature adaptation | Photosynthesis Research | 2014 | 756 |
| 38 | Alectinib versus crizotinib in patients with ALK -positive non-small-cell lung cancer (J-ALEX): an open-label, randomised phase 3 trial | Lancet, The | 2017 | 753 |
| 39 | Site of action of a Vero toxin (VT2) from Escherichia coli O157:H7 and of Shiga toxin on eukaryotic ribosomes. RNA N-glycosidase activity of the toxins | FEBS Journal | 1988 | 740 |
| 40 | Efficacy and safety of tocilizumab in patients with systemic-onset juvenile idiopathic arthritis: a randomised, double-blind, placebo-controlled, withdrawal phase III trial | Lancet, The | 2008 | 734 |
| 41 | From The Cover: Integration of transcriptomics and metabolomics for understanding of global responses to nutritional stresses in Arabidopsis thaliana | Proceedings of the National Academy of Sciences of the United States of America | 2004 | 726 |
| 42 | The physiological effects of Shinrin-yoku (taking in the forest atmosphere or forest bathing): evidence from field experiments in 24 forests across Japan | Environmental Health and Preventive Medicine | 2010 | 724 |
| 43 | Differential Tumor Surveillance by Natural Killer (Nk) and Nkt Cells | Journal of Experimental Medicine | 2000 | 720 |
| 44 | Sulfur Assimilation in Photosynthetic Organisms: Molecular Functions and Regulations of Transporters and Assimilatory Enzymes | Annual Review of Plant Biology | 2011 | 720 |
| 45 | Functional and Structural Outcome After Arthroscopic Full-Thickness Rotator Cuff Repair: Single-Row Versus Dual-Row Fixation | Arthroscopy - Journal of Arthroscopic and Related Surgery | 2005 | 713 |
| 46 | KAI1, a metastasis suppressor gene for prostate cancer on human chromosome 11p11.2 | Science | 1995 | 709 |
| 47 | THE MAMMALIAN CARBOXYLESTERASES: From Molecules to Functions | Annual Review of Pharmacology and Toxicology | 1998 | 690 |
| 48 | Modulation of cellular function by polyamines | International Journal of Biochemistry and Cell Biology | 2010 | 672 |
| 49 | Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis | Proceedings of the National Academy of Sciences of the United States of America | 2007 | 666 |
| 50 | Remote sensing and GIS for mapping and monitoring land cover and land-use changes in the Northwestern coastal zone of Egypt | Applied Geography | 2007 | 660 |
