| Wind-up of spinal cord neurones and pain sensation: much ado about something? | Progress in Neurobiology | 2000 | 536 |
| Stimulation by 1,25-dihydroxyvitamin D3 of insulin receptor expression and insulin responsiveness for glucose transport in U-937 human promonocytic cells | Endocrine Journal | 2000 | 295 |
| Pathologic gambling in Parkinson's disease: a behavioral manifestation of pharmacologic treatment? | Movement Disorders | 2000 | 251 |
| Comparison of estrogen concentrations, estrone sulfatase and aromatase activities in normal, and in cancerous, human breast tissues | Journal of Steroid Biochemistry and Molecular Biology | 2000 | 239 |
| Leaf structure and anatomy as related to leaf mass per area variation in seedlings of a wide range of woody plant species and types | Oecologia | 2000 | 195 |
| Effect of propranolol on the factors promoting bacterial translocation in cirrhotic rats with ascites | Hepatology | 2000 | 181 |
| Freeze-drying of polycaprolactone and poly(D,L-lactic-glycolic) nanoparticles induce minor particle size changes affecting the oral pharmacokinetics of loaded drugs | European Journal of Pharmaceutics and Biopharmaceutics | 2000 | 166 |
| Deficits in visceral pain and hyperalgesia of mice with a disruption of the tachykinin NK1 receptor gene | Neuroscience | 2000 | 161 |
| Multicenter randomized controlled trial of terlipressin versus sclerotherapy in the treatment of acute variceal bleeding: the TEST study | Hepatology | 2000 | 154 |
| Increasing the hematocrit has a beneficial effect on quality of life and is safe in selected hemodialysis patients. Spanish Cooperative Renal Patients Quality of Life Study Group of the Spanish Society of Nephrology | Journal of the American Society of Nephrology: JASN | 2000 | 152 |
| Outbreak of a multiresistant Klebsiella pneumoniae strain in an intensive care unit: antibiotic use as risk factor for colonization and infection | Clinical Infectious Diseases | 2000 | 135 |
| Prognostic influence of tumor-associated eosinophilic infiltrate in colorectal carcinoma | Cancer | 2000 | 116 |
| Chlororespiration and poising of cyclic electron transport. Plastoquinone as electron transporter between thylakoid NADH dehydrogenase and peroxidase | Journal of Biological Chemistry | 2000 | 115 |
| A new fossil resin with biological inclusions in Lower Cretaceous deposits from Álava (northern Spain, Basque-Cantabrian Basin) | Journal of Paleontology | 2000 | 102 |
| Reagentless biosensors based on self-deposited redox polyelectrolyte-oxidoreductases architectures | Biosensors and Bioelectronics | 2000 | 95 |
| Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes | Drug Delivery | 2000 | 84 |
| A parasitological survey of wild red foxes (Vulpes vulpes) from the province of Guadalajara, Spain | Veterinary Parasitology | 2000 | 82 |
| 4E binding protein 1 expression is inversely correlated to the progression of gastrointestinal cancers | International Journal of Biochemistry and Cell Biology | 2000 | 81 |
| Effect of silicon supplement on osteopenia induced by ovariectomy in rats | Calcified Tissue International | 2000 | 80 |
| Molecular characterisation of the inactive allele of the gene Glu-A1 and the development of a set of AS-PCR markers for HMW glutenins of wheat | Theoretical and Applied Genetics | 2000 | 80 |
| Reactive oxygen species induce proliferation of bovine aortic endothelial cells | Journal of Cardiovascular Pharmacology | 2000 | 80 |
| Identification of different chromatin classes in wheat using in situ hybridization with simple sequence repeat oligonucleotides | Theoretical and Applied Genetics | 2000 | 79 |
| Induction of T-cell mitogenic unresponsiveness by recombinant human granulocyte colony-stimulating factor – a reply | British Journal of Cancer | 2000 | 78 |
| Optimization strategy and validation of one chromatographic method as approach to determine the phenolic compounds from different sources | Journal of Chromatography A | 2000 | 77 |
| HCV-associated thrombocytopenia: clinical characteristics and platelet response after recombinant alpha2b-interferon therapy | British Journal of Haematology | 2000 | 77 |
